Oncogenic HOXB8 is driven by MYC-regulated super-e... (ID 496312) - BioProject

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Accession: PRJNA496312 ID: 496312

Oncogenic HOXB8 is driven by MYC-regulated super-enhancer and potentiates colorectal cancer invasiveness via BACH1 [RNA-seq] (human)

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This project is a component of the Oncogenic HOXB8 is driven by MYC-regulated super-enhancer and potentiates colorectal cancer invasiveness via BACH1

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1 additional project is a component of the Oncogenic HOXB8 is driven by MYC-regulated super-enhancer and potentiates colorectal cancer invasiveness via BACH1.

90127 additional projects are related by organism.

HOXB8 acts as a transcription facor, thus we knock down HOXB8 gene by doxycycline induced shRNA in colon cancer cells and profiled the change of transcriptome after knocking down HOXB8 Overall design: Two independent shRNAs targeting HOXB8 were stably transduced into HCT116 cells. More...

Accession	PRJNA496312; GEO: GSE121207
Data Type	Transcriptome or Gene expression
Scope	Multiisolate
Organism	Homo sapiens[Taxonomy ID: 9606] Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo; Homo sapiens
Publications	Ying Y et al., "Oncogenic HOXB8 is driven by MYC-regulated super-enhancer and potentiates colorectal cancer invasiveness via BACH1.", Oncogene, 2020 Jan;39(5):1004-1017
Submission	Registration date: 14-Oct-2018 Health Science Center, Shenzhen University
Relevance	Medical

Project Data:

Resource Name	Number of Links
Sequence data
SRA Experiments	8
Publications
PubMed	1
Other datasets
BioSample	8
GEO DataSets	1

GEO Data Details

Parameter	Value
Data volume, Supplementary Mbytes	4

SRA Data Details

Parameter	Value
Data volume, Gbases	10
Data volume, Mbytes	5473

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Oncogenic HOXB8 is driven by MYC-regulated super-enhancer and potentiates colorectal cancer invasiveness via BACH1 [RNA-seq] (human)

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