AAV-delivered suppressor tRNA overcomes a nonsense... (ID 743041) - BioProject

Display Settings:

Format

Summary
BioProject ID list
Accessions List

Send to:

Choose Destination

File
Clipboard
Collections
My Bibliography

Links from BioSample

Accession: PRJNA743041 ID: 743041

AAV-delivered suppressor tRNA overcomes a nonsense mutation in mice (amplicon) (house mouse)

See Genome Information for Mus musculus

Navigate Up

This project is a component of the AAV-delivered suppressor tRNA overcomes a nonsense mutation in mice

Navigate Across

4 additional projects are components of the AAV-delivered suppressor tRNA overcomes a nonsense mutation in mice.

66348 additional projects are related by organism.

In this study, we utilized a mouse model of mucopolysaccharidosis type I (MPS-I) carrying a homozygous nonsense mutation in the Idua gene (Idua-W401X, TGG→TAG) to develop rAAV-delivered sup-tRNA therapeutics that can overcome a pathogenic UAG premature termination codon (PTC). More...

Accession	PRJNA743041; GEO: GSE179270
Scope	Multiisolate
Organism	Mus musculus[Taxonomy ID: 10090] Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus; Mus musculus
Publications	Wang J et al., "AAV-delivered suppressor tRNA overcomes a nonsense mutation in mice.", Nature, 2022 Apr;604(7905):343-348
Submission	Registration date: 1-Jul-2021 Umass medical school
Relevance	Model Organism

Project Data:

Resource Name	Number of Links
Sequence data
SRA Experiments	14
Publications
PubMed	1
PMC	1
Other datasets
BioSample	14
GEO DataSets	1

GEO Data Details

Parameter	Value
Data volume, Supplementary Mbytes	1

SRA Data Details

Parameter	Value
Data volume, Mbases	256
Data volume, Mbytes	106

BioProject

Result Filters

Display Settings:

Send to:

Links from BioSample

AAV-delivered suppressor tRNA overcomes a nonsense mutation in mice (amplicon) (house mouse)

Supplemental Content

Related information

Recent activity