KRAP (Ki-ras-induced actin-interacting protein) is a cytoskeleton-associated protein and a ubiquitous protein among tissues, originally identified as a cancer-related molecule. KRAP-deficient (KRAP-/-) mice show enhanced metabolic rate, decreased adiposity, improved glucose tolerance, hypoinsulinemia and hypoleptinemia. KRAP-/- mice are also protected against high-fat diet-induced obesity and insulin resistance despite of hyperphagia.
This SuperSeries is composed of the SubSeries listed below.
Overall design: Refer to individual Series
| Accession | PRJNA110689; GEO: GSE13585 |
| Type | Umbrella project |
| Publications | Fujimoto T et al., "Altered energy homeostasis and resistance to diet-induced obesity in KRAP-deficient mice.", PLoS One, 2009;4(1):e4240 |
| Submission | Registration date: 22-Jan-2009
Faculty of medicine,Department of cell biology, fukuoka university |
| Relevance | Superseries |
Project Data:
| Resource Name | Number
of Links |
|---|
| Publications |
| PubMed | 1 |
| PMC | 1 |
| Other datasets |
| GEO DataSets | 5 |
GEO Data Details| Parameter | Value |
|---|
| Data volume, Spots | 541212 |
| Data volume, Processed Mbytes | 18 |
| Data volume, Supplementary Mbytes | 53 |
This project encompasses the following 2 sub-projects:
| Project Type | Number of Projects |
| Transcriptome or Gene expression | 2 |
BioProject
accession | Organism | Title |
|---|
| PRJNA113935 | Mus musculus | Expression data from BAT of the KRAP deficient mice (Faculty of medicine,Department...) | | PRJNA113937 | Mus musculus | Expression data from liver of the KRAP deficient mice (Faculty of medicine,Department...) |
|