Display Settings:


Send to:

Choose Destination

Links from PMC

Accession: PRJNA118389 ID: 118389

Mus musculus (house mouse)

Analysis of altered gene expressions in valproate-treated Disc1-L100P mutant mice

See Genome Information for Mus musculus
Microarray analysis revealed that changes in genes expressions are brain region-dependent; expression of several genes are affected by point mutation L100P, which was verified by RT-PCR (Lcn2, Cyr61, Slc6a12, Slc40a1, Egr2), a few genes are affected by genotype and valproate (Dusp1 and Purb), suggesting their role in valproate-induced benificial effect on sensorimotor gaiting in Disc1-L100P mutant mice. More...
AccessionPRJNA118389; GEO: GSE17735
Data TypeTranscriptome or Gene expression
OrganismMus musculus[Taxonomy ID: 10090]
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus; Mus musculus
PublicationsLipina TV et al., "Genetic and pharmacological evidence for schizophrenia-related Disc1 interaction with GSK-3.", Synapse, 2011 Mar;65(3):234-48
SubmissionRegistration date: 24-Nov-2009
Ontario Institute for Cancer Research
RelevanceModel Organism
Project Data:
Resource NameNumber
of Links
Other datasets
GEO DataSets1
GEO Data Details
Data volume, Spots1773093
Data volume, Processed Mbytes43
Data volume, Supplementary Mbytes4401

Supplemental Content

Recent activity

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

See more...
Support Center