Homo sapiens (ID 377564) - BioProject

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Accession: PRJNA377564 ID: 377564

Homo sapiens (human)

ChIPSeq data from melanoma cancer cell line CHL-1 after Bromodomain and extra terminal (Bet) domain inhibitor treatment

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Bromodomain and extra terminal domain (BET) inhibition reduces occupancy of BET-family proteins at promoter and enhancer sites finally leading to genome wide changes in gene transcription. More...

Accession	PRJNA377564; GEO: GSE95585
Data Type	Epigenomics
Scope	Multiisolate
Organism	Homo sapiens[Taxonomy ID: 9606] Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo; Homo sapiens
Publications	Gelato KA et al., "Super-enhancers define a proliferative PGC-1α-expressing melanoma subgroup sensitive to BET inhibition.", Oncogene, 2018 Jan 25;37(4):512-521
Submission	Registration date: 1-Mar-2017 Bayer Pharma AG
Relevance	Medical

Project Data:

Resource Name	Number of Links
Sequence data
SRA Experiments	18
Publications
PubMed	1
PMC	1
Other datasets
BioSample	18
GEO DataSets	1

GEO Data Details

Parameter	Value
Data volume, Supplementary Mbytes	12722

SRA Data Details

Parameter	Value
Data volume, Gbases	380
Data volume, Tbytes	0.15

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Homo sapiens (human)

ChIPSeq data from melanoma cancer cell line CHL-1 after Bromodomain and extra terminal (Bet) domain inhibitor treatment

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