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Metagenome-Assembled Genome: SRR20881975_bin.15_MetaWRAP_v1.3_MAG

Identifiers
BioSample: SAMEA114095538; SRA: ERS16079379
Organism
uncultured Eggerthella sp.
cellular organisms; Bacteria; Terrabacteria group; Actinomycetota; Coriobacteriia; Eggerthellales; Eggerthellaceae; Eggerthella; environmental samples
Attributes
broad-scale environmental contextHuman digestive system
collection date2019-04-17
environmental mediumfaeces
geographic locationUSA
investigation typemetagenome-assembled genome
isolation sourcehuman feces metagenome
project nameDespite the emerging success of immunotherapy in non-small-cell lung cancer (NSCLC), it re-mains clinically important to better identify patients who are likely to respond to treatment, espe-cially considering the existence of immune-related adverse events (irAEs). In recent years, the gut microbiome has been correlated with treatment response, but no predictive models relating the two have been developed. Findings from our current study showed that a functional profile of the human gut microbiome outperformed taxonomical results across different studies and can be uti-lized to establish a model with good predictive value in lung cancer immunotherapy.
sample nameSRR20881975_bin.15_MetaWRAP_v1.3_MAG
ENA-CHECKLISTERC000047
ENA-FIRST-PUBLIC2023-07-18T12:24:29Z
ENA-LAST-UPDATE2023-07-18T12:24:29Z
External IdSAMEA114095538
INSDC center aliasEMG
INSDC center nameEMG
INSDC first public2023-07-18T12:24:29Z
INSDC last update2023-07-18T12:24:29Z
INSDC statuspublic
Submitter IdSRR20881975_bin.15_MetaWRAP_v1.3_MAG
assembly qualityMany fragments with little to no review of assembly other than reporting of standard assembly statistics
assembly softwaremetaspades v3.15.3
binning parametersMaxBin2, MetaBat2, Concoct with default parameter of the metaWRAP pipeline. Bin refinement module used from metaWRAP with default parameters.
binning softwareMetaWRAP v1.3
broker nameEMG broker account, EMBL-EBI
completeness score100
completeness softwareCheckM
contamination score0.12
geographic location (latitude)41.65966
geographic location (longitude)-91.54766
local environmental contextcolon
metagenomic sourcehuman feces metagenome
sample derived fromSAMN30170369
scientific_nameuncultured Eggerthella sp.
sequencing methodIllumina HiSeq 4000
taxonomic classificationThe taxonomy of this Metagenome-Assembled Genome was originally computed with GTDBtk, which assigned the following taxonomic annotation: d__Bacteria;p__Actinobacteria;c__Coriobacteriia;o__Eggerthellales;f__Eggerthellaceae;g__Eggerthella;s__
taxonomic identity markermulti-marker approach
Description

This sample represents a Third Party Annotation (TPA) metagenome-assembled genome assembled from the metagenomic run SRR20881975 of study SRP390205.

BioProject
PRJEB63188
Retrieve all samples from this project

Submission
EBI; 2023-07-20
Accession:
SAMEA114095538
ID:
36650969

BioProject Nucleotide

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