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FGFR3 ligand binding and activation

FGFR3 is a receptor tyrosine kinase of the FGF receptor family, known to have a negative regulatory effect on long bone growth. Somatically, some of the same activating mutations are associated with hypochondroplasia, multiple myeloma, and cervical and vesical carcinoma.

from REACTOME source record: R-HSA-190239
Type: pathway
Taxonomic scope
organism-specific biosystem
Homo sapiens

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