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ARMS-mediated activation

ARMS (Ankyrin-Rich Membrane Spanning/Kidins 220) is a 220kD tetraspanning adaptor protein which becomes rapidly tyrosine phosphorylated by active Trk receptors. ARMS is another adaptor protein which is involved in the activation of Rap1 and the subsequent prolonged activation of the MAPK cascade.

from REACTOME source record: R-HSA-170984
Type: pathway
Taxonomic scope
organism-specific biosystem
Homo sapiens

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