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Bmal1:Clock,Npas2 activates circadian gene expression

Bmal1:Clock (Arntl:Clock) and Bmal1:Npas2 (Arntl:Npas2) heterodimers bind to sequence elements (E boxes) in the promoters of target genes and enhance transcription (Gekakis et al. 1998, reviewed in Munoz and Baler 2003).

from REACTOME source record: R-MMU-1368110
Type: pathway
Taxonomic scope
:
organism-specific biosystem
Organism
:
Mus musculus
BSID:
1368127

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