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Wnt/beta-catenin Signaling Pathway in Leukemia

The Wnt/Beta-catenin pathway mediates the transcription of proteins important for maintenance and growth of hematopoietic stem cells. The inhibition of Wnt leads to protein degradation through Beta-Catenin activation by the Axin/APC/CK1/GSK3B protein complex. This pathway is based on figure 5 from Misaghian et al.

from WikiPathways source record: WP3658
Type: pathway
Taxonomic scope
organism-specific biosystem

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