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Preimplantation Embryo

The source of this pathway is RNA-Seq data from single-cell pre-implantation embryos (Supplemental Table 1): http://0-www.nature.com.brum.beds.ac.uk/nsmb/journal/v20/n9/full/nsmb.2660.html Analysis options for running the single-cell analysis workflow in AltAnalyze (ICGS): * For optimal filtering (not too restrictive), change the Fold change filter cutoff from 10 to 100 and the Minimum number of samples differing from 3 to 2. * Change the Select the column clustering method to hopach. * The final ICGS cell cluster groups (hopach) were further analyzed to identify genes with restricted expression in one of the identified sub-populations using the MarkerFinder algorithm in AltAnalyze (RPKM>1). * MarkerFinder identified genes for each sub-population (e.g., 8-cell pattern 1) were further filtered for DNA-binding and RNA-binding factors, that are reported in this pathway.

from WikiPathways source record: WP3527
Type: pathway
Taxonomic scope
organism-specific biosystem

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