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Links from BioSystems

Items: 4

1.

PI3K-Akt signaling pathway

The phosphatidylinositol 3' -kinase(PI3K)-Akt signaling pathway is activated by many types of cellular stimuli or toxic insults and regulates fundamental cellular functions such as transcription, translation, proliferation, growth, and survival. The binding of growth factors to their...

Type
:
pathway
Taxonomic scope
:
conserved biosystem
2.

Endocytosis

Endocytosis is a mechanism for cells to remove ligands, nutrients, and plasma membrane (PM) proteins, and lipids from the cell surface, bringing them into the cell interior. Transmembrane proteins entering through clathrin-dependent endocytosis (CDE) have sequences in their cytoplasmic...

Type
:
pathway
Taxonomic scope
:
conserved biosystem
3.

Focal adhesion

Cell-matrix adhesions play essential roles in important biological processes including cell motility, cell proliferation, cell differentiation, regulation of gene expression and cell survival. At the cell-extracellular matrix contact points, specialized structures are formed and termed...

Type
:
pathway
Taxonomic scope
:
conserved biosystem
4.

Calcium signaling pathway

Ca2+ that enters the cell from the outside is a principal source of signal Ca2+. Entry of Ca2+ is driven by the presence of a large electrochemical gradient across the plasma membrane. Cells use this external source of signal Ca2+ by activating various entry channels with widely different...

Type
:
pathway
Taxonomic scope
:
conserved biosystem

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