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Items: 1 to 20 of 67

1.

high-affinity iron exporter complex

A protein complex which transports ferrous iron (Fe(III) or Fe3+) ions from the vacuole, the main storage component of intracellular free iron, into the cytoplasm in a low iron environment. Synonyms: FET5-FTH1 high affinity iron exporter complex; FET5-FTH1 high-affinity iron exporter...

Type
:
structural_complex
Taxonomic scope
:
conserved biosystem
BSID:
1492408
GO
: GO:0061841
2.

Tapasin-ERp57 complex

Subunit of the MHC class I peptide loading complex (GO:0042824) (=PLC) involved in the assembly of the heavy-chain-beta2-microglobulin dimers of the MHC class I molecules that fold with eight to ten residue peptides in the endoplasmic reticulum. Required for the inhibition of the...

Type
:
structural_complex
Taxonomic scope
:
conserved biosystem
BSID:
1427919
GO
: GO:0061779
3.

H-gal-GP complex

A membrane glycoprotein complex with aspartyl proteinase and metalloproteinase activity which is expressed in the gut. An example of this is found in the nematode Haemonchus contortus. Synonyms: Haemonchus galactose-containing glycoprotein complex; galactose-containing glycoprotein...

Type
:
structural_complex
Taxonomic scope
:
conserved biosystem
BSID:
1310824
GO
: GO:1990850
4.

chloroplast thylakoid membrane protein complex

A protein complex that is part of a chloroplast thylakoid membrane.

Type
:
structural_complex
Taxonomic scope
:
conserved biosystem
BSID:
1272080
GO
: GO:0098807
5.

respiratory chain complex

Any protein complex that is part of a respiratory chain

Type
:
structural_complex
Taxonomic scope
:
conserved biosystem
BSID:
1272076
GO
: GO:0098803
6.

inner mitochondrial membrane protein complex

Any protein complex that is part of the inner mitochondrial membrane.

Type
:
structural_complex
Taxonomic scope
:
conserved biosystem
BSID:
1272074
GO
: GO:0098800
7.

outer mitochondrial membrane protein complex

Any protein complex that is part of the outer mitochondrial membrane.

Type
:
structural_complex
Taxonomic scope
:
conserved biosystem
BSID:
1272073
GO
: GO:0098799
8.

plasma membrane protein complex

Any protein complex that is part of the plasma membrane.

Type
:
structural_complex
Taxonomic scope
:
conserved biosystem
BSID:
1272071
GO
: GO:0098797
9.

Derlin-1 retrotranslocation complex

A protein complex that functions in the retrotranslocation step of ERAD (ER-associated protein degradation), and includes at its core Derlin-1 oligomers forming a retrotranslocation channel. Synonyms: Derlin-1 complex; Derlin-1 protein dislocation complex; Derlin-1 retro-translocation...

Type
:
structural_complex
Taxonomic scope
:
conserved biosystem
BSID:
1272007
GO
: GO:0036513
10.

Derlin-1-VIMP complex

A protein complex containing, in mammals, Derlin-1 and VCP-interacting membrane protein (VIMP). The complex links the p97/VCP-containing ATPase complex with Derlin-1 during translocation of protein substrates from the endoplasmic reticulum to the cytosol for degradation by the cytosolic...

Type
:
structural_complex
Taxonomic scope
:
conserved biosystem
BSID:
1271996
GO
: GO:0036502
11.

phospholamban complex

A protein complex found as a homopentamer of the phospholamban (PLN) protein in the sarcoplasmic reticulum (SR) membrane of cardiomyocytes. Cardiac PLN is a main determinant of muscle contraction and relaxation, by regulating intracellular calcium levels. Synonyms: cardiac PLB complex;...

Type
:
structural_complex
Taxonomic scope
:
conserved biosystem
BSID:
1184597
GO
: GO:1990629
12.

ESCRT IV complex

An ESCRT complex that has AAA-ATPase activity and is involved in ESCRT-mediated intralumenal vesicle formation and the final stages of cytokinesis. The complex catalyzes disassembly of the ESCRT III filament around the neck of the budding vesicle in an ATP-driven reaction, resulting...

Type
:
structural_complex
Taxonomic scope
:
conserved biosystem
BSID:
1144994
GO
: GO:1990621
13.

IRE1-TRAF2-ASK1 complex

A protein complex of the endoplasmic reticulum membrane that consists of IRE1 (Inositol-requiring enzyme-1), TRAF2 (TNF receptor-associated factor 2) and ASK1 (Apoptosis signal-regulating kinase 1, a MAP3K). Synonym: ERN1-TRAF2-ASK1 complex;

Type
:
structural_complex
Taxonomic scope
:
conserved biosystem
BSID:
1134028
GO
: GO:1990604
14.

CUE1-UBC7 ubiquitin-conjugating enzyme complex

A protein complex capable of ubiquitin-conjugating enzyme activity during ER-associated protein degradation (ERAD). In S. cerevisiae, UBC7 is the ubiquitin-conjugating enzyme (E2) and requires binding to the ER surface by CUE1. Synonym: CUE1-UBC7 ubiquitin-conjugating enzyme (E2)...

Type
:
structural_complex
Taxonomic scope
:
conserved biosystem
BSID:
993454
GO
: GO:1990389
15.

STING complex

A protein dimer containing two STING monomers. It binds cyclic purine di-nucleotides. Activation of the sting complex by 2',5'-3'-5'-cyclic GMP-AMP activates nuclear transcription factor kB (NF-kB) and interferon regulatory factor 3 (IRF3) which then induce transcription of the genes...

Type
:
structural_complex
Taxonomic scope
:
conserved biosystem
BSID:
911531
GO
: GO:1990231
16.

Bam protein complex

Protein complex which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. In E. coli it is composed of BamABCDE, of the outer membrane protein BamA, and four lipoproteins BamB, BamC, BamD and BamE. BamA interacts directly with BamB and the BamCDE...

Type
:
structural_complex
Taxonomic scope
:
conserved biosystem
BSID:
781998
GO
: GO:1990063
17.

starch utilization system complex

A bacterial cell envelope-associated multiprotein system, which binds and degrades starch. Synonym: Sus complex;

Type
:
structural_complex
Taxonomic scope
:
conserved biosystem
BSID:
751715
GO
: GO:0044570
18.

ER membrane protein complex

A transmembrane protein complex that is involved in protein folding in the endoplasmic reticulum. In S. cerevisiae, it has six members: EMC1, EMC2, AIM27, EMC4, KRE27, and EMC6. Synonyms: EMC; endoplasmic reticulum membrane protein complex;

Type
:
structural_complex
Taxonomic scope
:
conserved biosystem
BSID:
517451
GO
: GO:0072546
19.

Ragulator complex

A protein complex that contains MAPKSP1 (MP1, Map2k1ip1), ROBLD3 (p14, Mapbpip), C11orf59 (p18), LAMTOR4 and LAMTOR5. The complex is anchored to lipid rafts in late endosome membranes via C11orf59, recruits mTORC1 to lysosomal membranes in amino acid signaling to mTORC1, constitutes...

Type
:
structural_complex
Taxonomic scope
:
conserved biosystem
BSID:
516905
GO
: GO:0071986
20.

clathrin complex

A protein complex that consists of three clathrin heavy chains and three clathrin light chains, organized into a symmetrical three-legged structure called a triskelion. In clathrin-coated vesicles clathrin is the main component of the coat and forms a polymeric mechanical scaffold...

Type
:
structural_complex
Taxonomic scope
:
conserved biosystem
BSID:
516363
GO
: GO:0071439

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