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Items: 1 to 20 of 27

1.

Glucagon signaling pathway

Glucagon is conventionally regarded as a counterregulatory hormone for insulin and plays a critical anti-hypoglycemic role by maintaining glucose homeostasis in both animals and humans. To increase blood glucose, glucagon promotes hepatic glucose output by increasing glycogenolysis...

Type
:
pathway
Taxonomic scope
:
organism-specific biosystem
Organism
:
Oryctolagus cuniculus
2.

Central carbon metabolism in cancer

Malignant transformation of cells requires specific adaptations of cellular metabolism to support growth and survival. In the early twentieth century, Otto Warburg established that there are fundamental differences in the central metabolic pathways operating in malignant tissue. He...

Type
:
pathway
Taxonomic scope
:
organism-specific biosystem
Organism
:
Oryctolagus cuniculus
3.

Viral carcinogenesis

There is a strong association between viruses and the development of human malignancies. We now know that at least six human viruses, Epstein-Barr virus (EBV), hepatitis B virus (HBV), hepatitis C virus (HCV), human papilloma virus (HPV), human T-cell lymphotropic virus (HTLV-1) and...

Type
:
pathway
Taxonomic scope
:
organism-specific biosystem
Organism
:
Oryctolagus cuniculus
4.

Type II diabetes mellitus

Insulin resistance is strongly associated with type II diabetes. "Diabetogenic" factors including FFA, TNFalpha and cellular stress induce insulin resistance through inhibition of IRS1 functions. Serine/threonine phosphorylation, interaction with SOCS, regulation of the expression,...

Type
:
pathway
Taxonomic scope
:
organism-specific biosystem
Organism
:
Oryctolagus cuniculus
5.

Glycolysis / Gluconeogenesis

Glycolysis is the process of converting glucose into pyruvate and generating small amounts of ATP (energy) and NADH (reducing power). It is a central pathway that produces important precursor metabolites: six-carbon compounds of glucose-6P and fructose-6P and three-carbon compounds...

Type
:
pathway
Taxonomic scope
:
organism-specific biosystem
Organism
:
Oryctolagus cuniculus
6.

Guanine ribonucleotide biosynthesis IMP => GDP,GTP

Pathway module; Nucleotide and amino acid metabolism; Purine metabolism

Type
:
pathway
Taxonomic scope
:
organism-specific biosystem
Organism
:
Oryctolagus cuniculus
7.

Adenine ribonucleotide biosynthesis, IMP => ADP,ATP

Pathway module; Nucleotide and amino acid metabolism; Purine metabolism

Type
:
pathway
Taxonomic scope
:
organism-specific biosystem
Organism
:
Oryctolagus cuniculus
8.

Glycolysis, core module involving three-carbon compounds

Pathway module; Carbohydrate and lipid metabolism; Central carbohydrate metabolism

Type
:
pathway
Taxonomic scope
:
organism-specific biosystem
Organism
:
Oryctolagus cuniculus
9.

Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate

Pathway module; Carbohydrate and lipid metabolism; Central carbohydrate metabolism

Type
:
pathway
Taxonomic scope
:
organism-specific biosystem
Organism
:
Oryctolagus cuniculus
10.

Biosynthesis of amino acids

This map presents a modular architecture of the biosynthesis pathways of twenty amino acids, which may be viewed as consisting of the core part and its extensions. The core part is the KEGG module for conversion of three-carbon compounds from glyceraldehyde-3P to pyruvate [MD:M00002],...

Type
:
pathway
Taxonomic scope
:
organism-specific biosystem
Organism
:
Oryctolagus cuniculus
11.

Carbon metabolism

Carbon metabolism is the most basic aspect of life. This map presents an overall view of central carbon metabolism, where the number of carbons is shown for each compound denoted by a circle, excluding a cofactor (CoA, CoM, THF, or THMPT) that is replaced by an asterisk. The map contains...

Type
:
pathway
Taxonomic scope
:
organism-specific biosystem
Organism
:
Oryctolagus cuniculus
12.

Pyruvate metabolism

Type
:
pathway
Taxonomic scope
:
organism-specific biosystem
Organism
:
Oryctolagus cuniculus
13.

Purine metabolism

Type
:
pathway
Taxonomic scope
:
organism-specific biosystem
Organism
:
Oryctolagus cuniculus
14.

Glucagon signaling pathway

Glucagon is conventionally regarded as a counterregulatory hormone for insulin and plays a critical anti-hypoglycemic role by maintaining glucose homeostasis in both animals and humans. To increase blood glucose, glucagon promotes hepatic glucose output by increasing glycogenolysis...

Type
:
pathway
Taxonomic scope
:
conserved biosystem
15.

Central carbon metabolism in cancer

Malignant transformation of cells requires specific adaptations of cellular metabolism to support growth and survival. In the early twentieth century, Otto Warburg established that there are fundamental differences in the central metabolic pathways operating in malignant tissue. He...

Type
:
pathway
Taxonomic scope
:
conserved biosystem
16.

Metabolic pathways

Type
:
pathway
Taxonomic scope
:
organism-specific biosystem
Organism
:
Oryctolagus cuniculus
17.

Viral carcinogenesis

There is a strong association between viruses and the development of human malignancies. We now know that at least six human viruses, Epstein-Barr virus (EBV), hepatitis B virus (HBV), hepatitis C virus (HCV), human papilloma virus (HPV), human T-cell lymphotropic virus (HTLV-1) and...

Type
:
pathway
Taxonomic scope
:
conserved biosystem
BSID:
662842
KEGG
: ko05203
18.

Type II diabetes mellitus

Insulin resistance is strongly associated with type II diabetes. "Diabetogenic" factors including FFA, TNFalpha and cellular stress induce insulin resistance through inhibition of IRS1 functions. Serine/threonine phosphorylation, interaction with SOCS, regulation of the expression,...

Type
:
pathway
Taxonomic scope
:
conserved biosystem
19.

Glycolysis / Gluconeogenesis

Glycolysis is the process of converting glucose into pyruvate and generating small amounts of ATP (energy) and NADH (reducing power). It is a central pathway that produces important precursor metabolites: six-carbon compounds of glucose-6P and fructose-6P and three-carbon compounds...

Type
:
pathway
Taxonomic scope
:
conserved biosystem
20.

Carbon metabolism

Carbon metabolism is the most basic aspect of life. This map presents an overall view of central carbon metabolism, where the number of carbons is shown for each compound denoted by a circle, excluding a cofactor (CoA, CoM, THF, or THMPT) that is replaced by an asterisk. The map contains...

Type
:
pathway
Taxonomic scope
:
conserved biosystem

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