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Items: 1 to 20 of 30

1.

Alcoholism

Alcoholism, also called dependence on alcohol (ethanol), is a chronic relapsing disorder that is progressive and has serious detrimental health outcomes. As one of the primary mediators of the rewarding effects of alcohol, dopaminergic ventral tegmental area (VTA) projections to the...

Type
:
pathway
Taxonomic scope
:
organism-specific biosystem
Organism
:
Mus musculus
2.

Systemic lupus erythematosus

Systemic lupus erythematosus (SLE) is a prototypic autoimmune disease characterised by the production of IgG autoantibodies that are specific for self-antigens, such as DNA, nuclear proteins and certain cytoplasmic components, in association with a diverse array of clinical manifestations....

Type
:
pathway
Taxonomic scope
:
organism-specific biosystem
Organism
:
Mus musculus
3.

NoRC negatively regulates rRNA expression

Only about half of the rRNA gene copies in a cell are expressed. The remaining copies are silenced by modifications to histones and DNA (reviewed in Santoro and Grummt 2001, Grummt 2007, Preuss and Pikaard 2007, Birch and Zomerdijk 2008, McStay and Grummt 2008, Grummt and Langst 2013)....

Type
:
pathway
Taxonomic scope
:
organism-specific biosystem
Organism
:
Mus musculus
4.

Meiotic Synapsis

Meiotic synapsis is the stable physical pairing of homologous chromosomes that begins in leptonema of prophase I and lasts until anaphase of prophase I. First, short segments of axial elements form along chromosomes. Telomeres then cluster at a region of the inner nuclear membrane...

Type
:
pathway
Taxonomic scope
:
organism-specific biosystem
Organism
:
Mus musculus
5.

Meiotic Recombination

Meiotic recombination exchanges segments of duplex DNA between chromosomal homologs, generating genetic diversity (reviewed in Handel and Schimenti 2010, Inagaki et al. 2010, Cohen et al. 2006). There are two forms of recombination: non-crossover (NCO) and crossover (CO). In mammals,...

Type
:
pathway
Taxonomic scope
:
organism-specific biosystem
Organism
:
Mus musculus
6.

Metalloprotease DUBs

computationally inferred pathway (not manually curated)

Type
:
pathway
Taxonomic scope
:
organism-specific biosystem
Organism
:
Mus musculus
7.

Ub-specific processing proteases

computationally inferred pathway (not manually curated)

Type
:
pathway
Taxonomic scope
:
organism-specific biosystem
Organism
:
Mus musculus
8.

UCH proteinases

computationally inferred pathway (not manually curated)

Type
:
pathway
Taxonomic scope
:
organism-specific biosystem
Organism
:
Mus musculus
9.

Meiotic synapsis

computationally inferred pathway (not manually curated)

Type
:
pathway
Taxonomic scope
:
organism-specific biosystem
Organism
:
Mus musculus
10.

DNA methylation

computationally inferred pathway (not manually curated)

Type
:
pathway
Taxonomic scope
:
organism-specific biosystem
Organism
:
Mus musculus
11.

NoRC negatively regulates rRNA expression

computationally inferred pathway (not manually curated)

Type
:
pathway
Taxonomic scope
:
organism-specific biosystem
Organism
:
Mus musculus
12.

ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression

computationally inferred pathway (not manually curated)

Type
:
pathway
Taxonomic scope
:
organism-specific biosystem
Organism
:
Mus musculus
13.

RMTs methylate histone arginines

computationally inferred pathway (not manually curated)

Type
:
pathway
Taxonomic scope
:
organism-specific biosystem
Organism
:
Mus musculus
14.

Activation of anterior HOX genes in hindbrain development during early embryogenesis

computationally inferred pathway (not manually curated)

Type
:
pathway
Taxonomic scope
:
organism-specific biosystem
Organism
:
Mus musculus
15.

Alcoholism

Alcoholism, also called dependence on alcohol (ethanol), is a chronic relapsing disorder that is progressive and has serious detrimental health outcomes. As one of the primary mediators of the rewarding effects of alcohol, dopaminergic ventral tegmental area (VTA) projections to the...

Type
:
pathway
Taxonomic scope
:
conserved biosystem
16.

Systemic lupus erythematosus

Systemic lupus erythematosus (SLE) is a prototypic autoimmune disease characterised by the production of IgG autoantibodies that are specific for self-antigens, such as DNA, nuclear proteins and certain cytoplasmic components, in association with a diverse array of clinical manifestations....

Type
:
pathway
Taxonomic scope
:
conserved biosystem
17.

Deubiquitination

computationally inferred pathway (not manually curated)

Type
:
pathway
Taxonomic scope
:
organism-specific biosystem
Organism
:
Mus musculus
18.

Mus musculus biological processes

Certain mouse pathways have been fully manually curated in Reactome in order to support the manual inference of well-conserved but less well-studied human pathways. These pathways include Circadian clock, Meiotic recombination, Meiotic synapsis, Signaling by leptin, Transcriptional...

Type
:
pathway
Taxonomic scope
:
organism-specific biosystem
Organism
:
Mus musculus
19.

Meiosis

computationally inferred pathway (not manually curated)

Type
:
pathway
Taxonomic scope
:
organism-specific biosystem
Organism
:
Mus musculus
20.

Negative epigenetic regulation of rRNA expression

computationally inferred pathway (not manually curated)

Type
:
pathway
Taxonomic scope
:
organism-specific biosystem
Organism
:
Mus musculus

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