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Links from GEO Profiles

Items: 1 to 20 of 24

1.

TYROBP Causal Network

Based on Figure 6A from Zhang et al. Converted from the original human network to mouse. Gimap2 and Lgals9 (light gray) have no mouse ortholog.

Type
:
pathway
Taxonomic scope
:
organism-specific biosystem
2.

Microglia Pathogen Phagocytosis Pathway

Pathogens are recognized by complement C1q or immunoglobulin (IgG) that bind to microglia complement receptors (e.g., ITGAM/ITGB2) or Fc-receptors (e.g., FCGR1) that signal via the immunoreceptor tyrosine-based activation motif (ITAM)-containing adaptor molecules TYROBP or FCER1G,...

Type
:
pathway
Taxonomic scope
:
organism-specific biosystem
3.

Classical antibody-mediated complement activation

computationally inferred pathway (not manually curated)

Type
:
pathway
Taxonomic scope
:
organism-specific biosystem
Organism
:
Mus musculus
4.

Creation of C4 and C2 activators

computationally inferred pathway (not manually curated)

Type
:
pathway
Taxonomic scope
:
organism-specific biosystem
Organism
:
Mus musculus
5.

Initial triggering of complement

computationally inferred pathway (not manually curated)

Type
:
pathway
Taxonomic scope
:
organism-specific biosystem
Organism
:
Mus musculus
6.

Complement cascade

computationally inferred pathway (not manually curated)

Type
:
pathway
Taxonomic scope
:
organism-specific biosystem
Organism
:
Mus musculus
7.

Innate Immune System

computationally inferred pathway (not manually curated)

Type
:
pathway
Taxonomic scope
:
organism-specific biosystem
Organism
:
Mus musculus
8.

Immune System

computationally inferred pathway (not manually curated)

Type
:
pathway
Taxonomic scope
:
organism-specific biosystem
Organism
:
Mus musculus
9.

Allograft Rejection

This pathway illustrates molecular interactions involved in the fundamental adaptive immune response for allograft destruction. This pathway was adapted in large part from the KEGG pathway http://www.genome.jp/kegg/pathway/hsa/hsa05330.html. In the initial step of this diagram, antigen...

Type
:
pathway
Taxonomic scope
:
organism-specific biosystem
10.

Pertussis

Pertussis, also known as whooping cough, is an acute respiratory infectious disease caused by a bacteria called Bordetella Pertussis. The characteristic symptoms are paroxysmal cough, inspiratory wheezing and post-tussive vomiting. Following the inhalation of respiratory secretions...

Type
:
pathway
Taxonomic scope
:
organism-specific biosystem
Organism
:
Mus musculus
11.

Pertussis

Pertussis, also known as whooping cough, is an acute respiratory infectious disease caused by a bacteria called Bordetella Pertussis. The characteristic symptoms are paroxysmal cough, inspiratory wheezing and post-tussive vomiting. Following the inhalation of respiratory secretions...

Type
:
pathway
Taxonomic scope
:
conserved biosystem
12.

Complement Activation, Classical Pathway

Type
:
pathway
Taxonomic scope
:
organism-specific biosystem
13.

Complement and Coagulation Cascades

Type
:
pathway
Taxonomic scope
:
organism-specific biosystem
14.

Oxidative Damage

This pathway shows how tissue is damaged when oxygen levels are not balanced and become too high.

Type
:
pathway
Taxonomic scope
:
organism-specific biosystem
15.

Staphylococcus aureus infection

Staphylococcus aureus can cause multiple forms of infections ranging from superficial skin infections to food poisoning and life-threatening infections. The organism has several ways to divert the effectiveness of the immune system: secreting immune modulating proteins that inhibit...

Type
:
pathway
Taxonomic scope
:
organism-specific biosystem
Organism
:
Mus musculus
16.

Staphylococcus aureus infection

Staphylococcus aureus can cause multiple forms of infections ranging from superficial skin infections to food poisoning and life-threatening infections. The organism has several ways to divert the effectiveness of the immune system: secreting immune modulating proteins that inhibit...

Type
:
pathway
Taxonomic scope
:
conserved biosystem
17.

Chagas disease (American trypanosomiasis)

Trypanosoma cruzi is an intracellular protozoan parasite that causes Chagas disease. The parasite life cycle involves hematophagous reduviid bugs as vectors. Once parasites enter the host body, they invade diverse host cells including cardiomyocytes. Establishment of infection depends...

Type
:
pathway
Taxonomic scope
:
organism-specific biosystem
Organism
:
Mus musculus
18.

Chagas disease (American trypanosomiasis)

Trypanosoma cruzi is an intracellular protozoan parasite that causes Chagas disease. The parasite life cycle involves hematophagous reduviid bugs as vectors. Once parasites enter the host body, they invade diverse host cells including cardiomyocytes. Establishment of infection depends...

Type
:
pathway
Taxonomic scope
:
conserved biosystem
19.

Prion diseases

Prion diseases, also termed transmissible spongiform encephalopathies (TSEs), are a group of fatal neurodegenerative diseases that affect humans and a number of other animal species. The etiology of these diseases is thought to be associated with the conversion of a normal protein,...

Type
:
pathway
Taxonomic scope
:
organism-specific biosystem
Organism
:
Mus musculus
20.

Prion diseases

Prion diseases, also termed transmissible spongiform encephalopathies (TSEs), are a group of fatal neurodegenerative diseases that affect humans and a number of other animal species. The etiology of these diseases is thought to be associated with the conversion of a normal protein,...

Type
:
pathway
Taxonomic scope
:
conserved biosystem

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