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Links from PubChem Compound

Items: 1 to 20 of 11468

1.

Lipid Droplet Metabolism

Lipid droplets are cytosolic organelles present in nearly all cell types. Initially they were considered only as inert lipid-storage sites, but now they are recognized to be involved in other functions and even associated with liver and kidney disease. Still, the mechanisms for lipid...

Type
:
pathway
Taxonomic scope
:
organism-specific biosystem
2.

Vitamin D Metabolism

Photochemical synthesis of vitamin D3 (cholecalciferol, D3) occurs cutaneously where pro-vitamin D3 (7-dehydrocholesterol) is converted to pre-vitamin D3 (pre-D3) in response to ultraviolet B (sunlight) exposure. DHCR7 encodes the enzyme 7-dehydrocholesterol (7-DHC) reductase, which...

Type
:
pathway
Taxonomic scope
:
organism-specific biosystem
3.

SREBP signalling

Sterol regulatory element-binding proteins (SREBPs) are membrane-bound proteins that act as transcription factors. They regulate lipid, especially cholesterol, biosynthesis and uptake at a transcriptional level to maintain cellular lipid homeostasis. In addition, SREBP appears to...

Type
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pathway
Taxonomic scope
:
organism-specific biosystem
4.

Composition of Lipid Particles

This particle describes the chemical composition of various lipid particles. See also WP430 and other pathways. Additional sources - A. Goldberg, Overview of Lipid Metabolism, 2015. http://www.msdmanuals.com/professional/endocrine-and-metabolic-disorders/lipid-disorders/overview...

Type
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pathway
Taxonomic scope
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organism-specific biosystem
5.

Aldosterone synthesis and secretion

Aldosterone is a steroid hormone synthesized in and secreted from the outer layer of the adrenal cortex, the zona glomerulosa. Aldosterone plays an important role in the regulation of systemic blood pressure through the absorption of sodium and water. Angiotensin II (Ang II), potassium...

Type
:
pathway
Taxonomic scope
:
conserved biosystem
6.

Ovarian steroidogenesis

The ovarian steroids, 17-beta estradiol (E2) and progesterone (P4), are critical for normal uterine function, establishment and maintenance of pregnancy, and mammary gland development. Furthermore, the local effects that are essential for normal ovarian physiology are dependent on...

Type
:
pathway
Taxonomic scope
:
conserved biosystem
7.

Sterol Regulatory Element-Binding Proteins (SREBP) signalling

Sterol regulatory element-binding proteins (SREBPs) are membrane-bound proteins that act as transcription factors. They regulate lipid, especially cholesterol, biosynthesis and uptake at a transcriptional level to maintain cellular lipid homeostasis. In addition, SREBP appears to...

Type
:
pathway
Taxonomic scope
:
organism-specific biosystem
8.

Vitamin digestion and absorption

Vitamins are a diverse and chemically unrelated group of organic substances that share a common feature of being essential for normal health and well-being. They catalyze numerous biochemical reactions. Because humans and other mammals cannot synthesize these compounds (except for...

Type
:
pathway
Taxonomic scope
:
conserved biosystem
9.

Cholesterol Biosynthesis

Cholesterol is a waxy steroid metabolite found in the cell membranes and transported in the blood plasma of all animals. It is an essential structural component of mammalian cell membranes, where it is required to establish proper membrane permeability and fluidity. In addition, cholesterol...

Type
:
pathway
Taxonomic scope
:
organism-specific biosystem
10.

Cholesterol Biosynthesis

Cholesterol is a waxy steroid metabolite found in the cell membranes and transported in the blood plasma of all animals. It is an essential structural component of mammalian cell membranes, where it is required to establish proper membrane permeability and fluidity. In addition, cholesterol...

Type
:
pathway
Taxonomic scope
:
organism-specific biosystem
11.

Cholesterol Biosynthesis

Cholesterol is a waxy steroid metabolite found in the cell membranes and transported in the blood plasma of all animals. It is an essential structural component of mammalian cell membranes, where it is required to establish proper membrane permeability and fluidity. In addition, cholesterol...

Type
:
pathway
Taxonomic scope
:
organism-specific biosystem
12.

Statin Pathway

Statins inhibit endogenous cholesterol production by competitive inhibition of HMG-CoA reductase (HMGCR), the enzyme that catalyzes conversion of HMG-CoA to mevalonate, an early rate-limiting step in cholesterol synthesis. This pathway delineates genes involved in statin pharmacogenomics,...

Type
:
pathway
Taxonomic scope
:
organism-specific biosystem
13.

Cholesterol Biosynthesis

Cholesterol is a waxy steroid metabolite found in the cell membranes and transported in the blood plasma of all animals. It is an essential structural component of mammalian cell membranes, where it is required to establish proper membrane permeability and fluidity. In addition, cholesterol...

Type
:
pathway
Taxonomic scope
:
organism-specific biosystem
14.

Vitamin D Metabolism

Photochemical synthesis of vitamin D3 (cholecalciferol, D3) occurs cutaneously where pro-vitamin D3 (7-dehydrocholesterol) is converted to pre-vitamin D3 (pre-D3) in response to ultraviolet B (sunlight) exposure. DHCR7 encodes the enzyme 7-dehydrocholesterol (7-DHC) reductase, which...

Type
:
pathway
Taxonomic scope
:
organism-specific biosystem
15.

Cholesterol Biosynthesis

Cholesterol is a waxy steroid metabolite found in the cell membranes and transported in the blood plasma of all animals. It is an essential structural component of mammalian cell membranes, where it is required to establish proper membrane permeability and fluidity. In addition, cholesterol...

Type
:
pathway
Taxonomic scope
:
organism-specific biosystem
16.

Cholesterol Biosynthesis

Cholesterol is a waxy steroid metabolite found in the cell membranes and transported in the blood plasma of all animals. It is an essential structural component of mammalian cell membranes, where it is required to establish proper membrane permeability and fluidity. In addition, cholesterol...

Type
:
pathway
Taxonomic scope
:
organism-specific biosystem
17.

Statin Pathway

Statins inhibit endogenous cholesterol production by competitive inhibition of HMG-CoA reductase (HMGCR), the enzyme that catalyzes conversion of HMG-CoA to mevalonate, an early rate-limiting step in cholesterol synthesis. This pathway delineates genes involved in statin pharmacogenomics,...

Type
:
pathway
Taxonomic scope
:
organism-specific biosystem
18.

Cholesterol metabolism

Cholesterol is essential for life - it's a required for the regulation of membrane fluidity. Cholesterol also serves as a precursor for many other biochemical pathways. Cholesterol is synthesized throughout the body but mainly in liver, intestines, adrenal glands and reproductive...

Type
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pathway
Taxonomic scope
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organism-specific biosystem
19.

Statin Pathway

What are statins? See Wikipedia at: http://en.wikipedia.org/wiki/Statin More about this pathway and statins: https://www.pharmgkb.org/do/serve?objId=PA2031&objCls=Pathway

Type
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pathway
Taxonomic scope
:
organism-specific biosystem
20.

Cholesterol Biosynthesis

Cholesterol is a waxy steroid metabolite found in the cell membranes and transported in the blood plasma of all animals. It is an essential structural component of mammalian cell membranes, where it is required to establish proper membrane permeability and fluidity. In addition, cholesterol...

Type
:
pathway
Taxonomic scope
:
organism-specific biosystem

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