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Links from Protein

Items: 1 to 20 of 318

1.

Signaling pathways regulating pluripotency of stem cells

Pluripotent stem cells (PSCs) are basic cells with an indefinite self-renewal capacity and the potential to generate all the cell types of the three germinal layers. The types of PSCs known to date include embryonic stem (ES) and induced pluripotent stem (iPS) cells. ES cells are...

Type
:
pathway
Taxonomic scope
:
organism-specific biosystem
Organism
:
Homo sapiens
2.

Preimplantation Embryo

The source of this pathway is RNA-Seq data from single-cell pre-implantation embryos (Supplemental Table 1): http://0-www.nature.com.brum.beds.ac.uk/nsmb/journal/v20/n9/full/nsmb.2660.html Analysis options for running the single-cell analysis workflow in AltAnalyze (ICGS): * For optimal filtering...

Type
:
pathway
Taxonomic scope
:
organism-specific biosystem
3.

Mesodermal Commitment Pathway

Model depicting mesodermal specification based on the literature and highly enriched gene expression profiles via comparison across dozens of independent induced and embryonic pluripotent stem cell lines, following differentiation to multiple lineages (ectoderm, mesoderm, endoderm,...

Type
:
pathway
Taxonomic scope
:
organism-specific biosystem
4.

Signaling pathways regulating pluripotency of stem cells

Pluripotent stem cells (PSCs) are basic cells with an indefinite self-renewal capacity and the potential to generate all the cell types of the three germinal layers. The types of PSCs known to date include embryonic stem (ES) and induced pluripotent stem (iPS) cells. ES cells are...

Type
:
pathway
Taxonomic scope
:
conserved biosystem
BSID:
1033502
KEGG
: ko04550
5.

sequence-specific double-stranded DNA binding

Interacting selectively and non-covalently with double-stranded DNA of a specific nucleotide composition, e.g. GC-rich DNA binding, or with a specific sequence motif or type of DNA, e.g. promotor binding or rDNA binding. Synonym: sequence-specific dsDNA binding;

Type
:
functional_set
Taxonomic scope
:
conserved biosystem
BSID:
1310813
GO
: GO:1990837
6.

negative regulation of nucleic acid-templated transcription

Any process that stops, prevents or reduces the frequency, rate or extent of nucleic acid-templated transcription. Synonyms: down regulation of nucleic acid-templated transcription; down-regulation of nucleic acid-templated transcription; downregulation of nucleic acid-templated transcription;...

Type
:
pathway
Taxonomic scope
:
conserved biosystem
BSID:
1129334
GO
: GO:1903507
7.

regulation of nucleic acid-templated transcription

Any process that modulates the frequency, rate or extent of nucleic acid-templated transcription.

Type
:
pathway
Taxonomic scope
:
conserved biosystem
BSID:
1129333
GO
: GO:1903506
8.

maintenance of cell number

Any process by which the numbers of cells of a particular type in a tissue are maintained.

Type
:
pathway
Taxonomic scope
:
conserved biosystem
BSID:
1022128
GO
: GO:0098727
9.

negative regulation of RNA biosynthetic process

Any process that stops, prevents or reduces the frequency, rate or extent of RNA biosynthetic process. Synonyms: down regulation of RNA anabolism; down regulation of RNA biosynthesis; down regulation of RNA biosynthetic process; down regulation of RNA formation; down regulation of...

Type
:
pathway
Taxonomic scope
:
conserved biosystem
BSID:
948122
GO
: GO:1902679
10.

regulation of RNA biosynthetic process

Any process that modulates the frequency, rate or extent of RNA biosynthetic process. Synonyms: regulation of RNA anabolism; regulation of RNA biosynthesis; regulation of RNA formation; regulation of RNA synthesis;

Type
:
pathway
Taxonomic scope
:
conserved biosystem
BSID:
755247
GO
: GO:2001141
11.

organic cyclic compound binding

Interacting selectively and non-covalently with an organic cyclic compound, any molecular entity that contains carbon arranged in a cyclic molecular structure.

Type
:
functional_set
Taxonomic scope
:
conserved biosystem
BSID:
752660
GO
: GO:0097159
12.

reproductive system development

The progression of the reproductive system over time from its formation to the mature structure. The reproductive system consists of the organs that function in reproduction.

Type
:
pathway
Taxonomic scope
:
conserved biosystem
BSID:
752201
GO
: GO:0061458
13.

single-organism developmental process

A biological process whose specific outcome is the progression of an integrated living unit: an anatomical structure (which may be a subcellular structure, cell, tissue, or organ), or organism over time from an initial condition to a later condition, involving only one organism.

Type
:
pathway
Taxonomic scope
:
conserved biosystem
BSID:
751909
GO
: GO:0044767
14.

single-organism transport

The directed movement of substances (such as macromolecules, small molecules, ions) into, out of or within a cell, or between cells, or within a multicellular organism by means of some agent such as a transporter or pore, involving a single organism.

Type
:
pathway
Taxonomic scope
:
conserved biosystem
BSID:
751907
GO
: GO:0044765
15.

single organism reproductive process

A biological process that directly contributes to the process of producing new individuals, involving a single organism.

Type
:
pathway
Taxonomic scope
:
conserved biosystem
BSID:
751845
GO
: GO:0044702
16.

transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding

Interacting selectively and non-covalently with a sequence of DNA that is in the regulatory region for RNA polymerase II (RNAP II) in order to stop, prevent, or reduce the frequency, rate or extent of transcription from an RNA polymerase II promoter. Synonym: RNA polymerase II transcription...

Type
:
functional_set
Taxonomic scope
:
conserved biosystem
BSID:
750779
GO
: GO:0001227
17.

positive regulation of stem cell proliferation

Any process that activates or increases the frequency, rate or extent of stem cell proliferation.

Type
:
pathway
Taxonomic scope
:
conserved biosystem
BSID:
519287
GO
: GO:2000648
18.

regulation of multicellular organismal development

Any process that modulates the frequency, rate or extent of multicellular organismal development.

Type
:
pathway
Taxonomic scope
:
conserved biosystem
BSID:
518675
GO
: GO:2000026
19.

cellular senescence

A cell aging process stimulated in response to cellular stress, whereby normal cells lose the ability to divide through irreversible cell cycle arrest.

Type
:
pathway
Taxonomic scope
:
conserved biosystem
BSID:
518538
GO
: GO:0090398
20.

circulatory system development

The process whose specific outcome is the progression of the circulatory system over time, from its formation to the mature structure. The circulatory system is the organ system that passes nutrients (such as amino acids and electrolytes), gases, hormones, blood cells, etc. to and...

Type
:
pathway
Taxonomic scope
:
conserved biosystem
BSID:
517275
GO
: GO:0072359

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