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Links from Protein

Items: 1 to 20 of 87

1.

HIF-1 signaling pathway

Hypoxia-inducible factor 1 (HIF-1) is a transcription factor that functions as a master regulator of oxygen homeostasis. It consists of two subunits: an inducibly-expressed HIF-1alpha subunit and a constitutively-expressed HIF-1beta subunit. Under normoxia, HIF-1 alpha undergoes hydroxylation...

Type
:
pathway
Taxonomic scope
:
organism-specific biosystem
Organism
:
Mus musculus
2.

Renal cell carcinoma

Renal cell cancer (RCC) accounts for ~3% of human malignancies and its incidence appears to be rising. Although most cases of RCC seem to occur sporadically, an inherited predisposition to renal cancer accounts for 1-4% of cases. RCC is not a single disease, it has several morphological...

Type
:
pathway
Taxonomic scope
:
organism-specific biosystem
Organism
:
Mus musculus
3.

Ubiquitin mediated proteolysis

Protein ubiquitination plays an important role in eukaryotic cellular processes. It mainly functions as a signal for 26S proteasome dependent protein degradation. The addition of ubiquitin to proteins being degraded is performed by a reaction cascade consisting of three enzymes, named...

Type
:
pathway
Taxonomic scope
:
organism-specific biosystem
Organism
:
Mus musculus
4.

ECV complex

Structural complex; Genetic information processing; Ubiquitin system

Type
:
structural_complex
Taxonomic scope
:
organism-specific biosystem
Organism
:
Mus musculus
BSID:
421847
KEGG
: mmu_M00383
5.

Pathways in cancer

Type
:
pathway
Taxonomic scope
:
organism-specific biosystem
Organism
:
Mus musculus
6.

Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha

computationally inferred pathway (not manually curated)

Type
:
pathway
Taxonomic scope
:
organism-specific biosystem
Organism
:
Mus musculus
7.

Renal cell carcinoma

Renal cell cancer (RCC) accounts for ~3% of human malignancies and its incidence appears to be rising. Although most cases of RCC seem to occur sporadically, an inherited predisposition to renal cancer accounts for 1-4% of cases. RCC is not a single disease, it has several morphological...

Type
:
pathway
Taxonomic scope
:
conserved biosystem
8.

Ubiquitin mediated proteolysis

Protein ubiquitination plays an important role in eukaryotic cellular processes. It mainly functions as a signal for 26S proteasome dependent protein degradation. The addition of ubiquitin to proteins being degraded is performed by a reaction cascade consisting of three enzymes, named...

Type
:
pathway
Taxonomic scope
:
conserved biosystem
9.

Regulation of Hypoxia-inducible Factor (HIF) by oxygen

computationally inferred pathway (not manually curated)

Type
:
pathway
Taxonomic scope
:
organism-specific biosystem
Organism
:
Mus musculus
10.

Cellular responses to stress

computationally inferred pathway (not manually curated)

Type
:
pathway
Taxonomic scope
:
organism-specific biosystem
Organism
:
Mus musculus
11.

ubiquitin-like protein ligase activity

Catalysis of the transfer of a ubiquitin-like protein (ULP) to a substrate protein via the reaction X-ULP + S --> X + S-ULP, where X is either an E2 or E3 enzyme, the X-ULP linkage is a thioester bond, and the S-ULP linkage is an isopeptide bond between the C-terminal glycine of ULP...

Type
:
functional_set
Taxonomic scope
:
conserved biosystem
BSID:
1129228
GO
: GO:0061659
12.

macromolecular complex binding

Interacting selectively and non-covalently with any macromolecular complex.

Type
:
functional_set
Taxonomic scope
:
conserved biosystem
BSID:
1129214
GO
: GO:0044877
13.

ubiquitin protein ligase activity

Catalysis of the transfer of ubiquitin to a substrate protein via the reaction X-ubiquitin + S -> X + S-ubiquitin, where X is either an E2 or E3 enzyme, the X-ubiquitin linkage is a thioester bond, and the S-ubiquitin linkage is an amide bond: an isopeptide bond between the C-terminal...

Type
:
functional_set
Taxonomic scope
:
conserved biosystem
BSID:
987826
GO
: GO:0061630
14.

transferase complex

A protein complex capable of catalyzing the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from one compound (generally regarded as the donor) to another compound (generally regarded as the acceptor).

Type
:
structural_complex
Taxonomic scope
:
conserved biosystem
BSID:
911534
GO
: GO:1990234
15.

catalytic complex

A protein complex which is capable of catalytic activity. Synonym: enzyme complex;

Type
:
structural_complex
Taxonomic scope
:
conserved biosystem
BSID:
911482
GO
: GO:1902494
16.

ECV complex

Structural complex; Genetic information processing; Ubiquitin system

Type
:
structural_complex
Taxonomic scope
:
conserved biosystem
BSID:
890606
KEGG
: M00383
17.

XPodNet - protein-protein interactions in the podocyte expanded by STRING

XPodNet is a larger version of PodNet. Interactions from STRING database have been added to PodNet to build XPodNet. Hence, not all interactions found in XPodNet do necessarily have to be curated.

Type
:
pathway
Taxonomic scope
:
organism-specific biosystem
18.

ubiquitin-like protein ligase binding

Interacting selectively and non-covalently with a ubiquitin-like protein ligase, such as ubiquitin-ligase. Synonyms: E3 protein ligase binding; small conjugating protein ligase binding;

Type
:
functional_set
Taxonomic scope
:
conserved biosystem
BSID:
751602
GO
: GO:0044389
19.

protein modification process

The covalent alteration of one or more amino acids occurring in proteins, peptides and nascent polypeptides (co-translational, post-translational modifications). Includes the modification of charged tRNAs that are destined to occur in a protein (pre-translation modification). Synonym:...

Type
:
pathway
Taxonomic scope
:
conserved biosystem
BSID:
751131
GO
: GO:0036211
20.

protein modification by small protein conjugation or removal

A protein modification process in which one or more groups of a small protein, such as ubiquitin or a ubiquitin-like protein, are covalently attached to or removed from a target protein.

Type
:
pathway
Taxonomic scope
:
conserved biosystem
BSID:
515577
GO
: GO:0070647

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