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Links from Protein

Items: 1 to 20 of 195

1.

PTK6 promotes HIF1A stabilization

HBEGF-stimulated formation of EGFR heterodimers with GPNMB triggers PTK6-mediated phosphorylation and stabilization of the hypoxia inducible factor 1 alpha (HIF1A) under normoxic conditions. This process depends on the presence of a long non-coding RNA LINC01139 (LINK-A) (Lin et al....

Type
:
pathway
Taxonomic scope
:
organism-specific biosystem
Organism
:
Homo sapiens
2.

Signaling by PTK6

PTK6 (BRK) is an oncogenic non-receptor tyrosine kinase that functions downstream of ERBB2 (HER2) (Xiang et al. 2008, Peng et al. 2015) and other receptor tyrosine kinases, such as EGFR (Kamalati et al. 1996) and MET (Castro and Lange 2010). Since ERBB2 forms heterodimers with EGFR...

Type
:
pathway
Taxonomic scope
:
organism-specific biosystem
Organism
:
Homo sapiens
3.

intracellular vesicle

Any vesicle that is part of the intracellular region.

Type
:
structural_complex
Taxonomic scope
:
conserved biosystem
BSID:
1384516
GO
: GO:0097708
4.

Signal Transduction

Signal transduction is a process in which extracellular signals elicit changes in cell state and activity. Transmembrane receptors sense changes in the cellular environment by binding ligands, such as hormones and growth factors, or reacting to other types of stimuli, such as light....

Type
:
pathway
Taxonomic scope
:
organism-specific biosystem
Organism
:
Homo sapiens
5.

molecular function regulator

A molecular function that modulates the activity of a gene product or complex. Examples include enzyme regulators and channel regulators.

Type
:
functional_set
Taxonomic scope
:
conserved biosystem
BSID:
1133933
GO
: GO:0098772
6.

negative regulation of tumor necrosis factor superfamily cytokine production

Any process that stops, prevents or reduces the frequency, rate or extent of tumor necrosis factor superfamily cytokine production. Synonyms: down regulation of TNF superfamily production; down regulation of TNFSF cytokine production; down regulation of tumor necrosis factor superfamily...

Type
:
pathway
Taxonomic scope
:
conserved biosystem
BSID:
1129382
GO
: GO:1903556
7.

macromolecular complex binding

Interacting selectively and non-covalently with any macromolecular complex.

Type
:
functional_set
Taxonomic scope
:
conserved biosystem
BSID:
1129214
GO
: GO:0044877
8.

negative regulation of leukocyte cell-cell adhesion

Any process that stops, prevents or reduces the frequency, rate or extent of leukocyte cell-cell adhesion. Synonyms: down regulation of leukocyte adhesion; down regulation of leukocyte cell adhesion; down regulation of leukocyte cell-cell adhesion; down-regulation of leukocyte adhesion;...

Type
:
pathway
Taxonomic scope
:
conserved biosystem
BSID:
987839
GO
: GO:1903038
9.

negative regulation of cell cycle G1/S phase transition

Any process that stops, prevents or reduces the frequency, rate or extent of cell cycle G1/S phase transition. Synonyms: down regulation of cell cycle G1/S phase transition; down-regulation of cell cycle G1/S phase transition; downregulation of cell cycle G1/S phase transition; inhibition...

Type
:
pathway
Taxonomic scope
:
conserved biosystem
BSID:
982377
GO
: GO:1902807
10.

regulation of cell cycle G1/S phase transition

Any process that modulates the frequency, rate or extent of cell cycle G1/S phase transition.

Type
:
pathway
Taxonomic scope
:
conserved biosystem
BSID:
982376
GO
: GO:1902806
11.

positive regulation of intracellular signal transduction

Any process that activates or increases the frequency, rate or extent of intracellular signal transduction. Synonyms: GO:0010740; activation of intracellular signal transduction; activation of intracellular signal transduction pathway; activation of intracellular signaling cascade;...

Type
:
pathway
Taxonomic scope
:
conserved biosystem
BSID:
921132
GO
: GO:1902533
12.

regulation of intracellular signal transduction

Any process that modulates the frequency, rate or extent of intracellular signal transduction. Synonyms: GO:0010627; regulation of intracellular protein kinase cascade; regulation of intracellular signal transduction pathway; regulation of intracellular signaling cascade; regulation...

Type
:
pathway
Taxonomic scope
:
conserved biosystem
BSID:
921130
GO
: GO:1902531
13.

negative regulation of mitotic cell cycle phase transition

Any process that stops, prevents or reduces the frequency, rate or extent of mitotic cell cycle phase transition. Synonyms: down regulation of mitotic cell cycle phase transition; down-regulation of mitotic cell cycle phase transition; downregulation of mitotic cell cycle phase transition;...

Type
:
pathway
Taxonomic scope
:
conserved biosystem
BSID:
781980
GO
: GO:1901991
14.

regulation of mitotic cell cycle phase transition

Any process that modulates the frequency, rate or extent of mitotic cell cycle phase transition. Synonym: mitotic cell cycle control;

Type
:
pathway
Taxonomic scope
:
conserved biosystem
BSID:
781979
GO
: GO:1901990
15.

regulation of cell cycle phase transition

Any process that modulates the frequency, rate or extent of cell cycle phase transition. Synonyms: cell cycle control; regulation of cell cycle transition;

Type
:
pathway
Taxonomic scope
:
conserved biosystem
BSID:
781976
GO
: GO:1901987
16.

regulation of vasculature development

Any process that modulates the frequency, rate or extent of vasculature development. Synonym: regulation of vascular system development;

Type
:
pathway
Taxonomic scope
:
conserved biosystem
BSID:
754304
GO
: GO:1901342
17.

negative regulation of neuron death

Any process that stops, prevents or reduces the frequency, rate or extent of neuron death. Synonyms: down regulation of neuron cell death; down regulation of neuron death; down regulation of neuronal cell death; down-regulation of neuron cell death; down-regulation of neuron death;...

Type
:
pathway
Taxonomic scope
:
conserved biosystem
BSID:
754182
GO
: GO:1901215
18.

regulation of neuron death

Any process that modulates the frequency, rate or extent of neuron death. Synonyms: regulation of neuron cell death; regulation of neuronal cell death;

Type
:
pathway
Taxonomic scope
:
conserved biosystem
BSID:
754181
GO
: GO:1901214
19.

carbohydrate derivative binding

Interacting selectively and non-covalently with a carbohydrate derivative.

Type
:
functional_set
Taxonomic scope
:
conserved biosystem
BSID:
752867
GO
: GO:0097367
20.

single-organism developmental process

A biological process whose specific outcome is the progression of an integrated living unit: an anatomical structure (which may be a subcellular structure, cell, tissue, or organ), or organism over time from an initial condition to a later condition, involving only one organism.

Type
:
pathway
Taxonomic scope
:
conserved biosystem
BSID:
751909
GO
: GO:0044767

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