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Links from Nucleotide

Items: 1 to 20 of 442

1.

plasma membrane bounded cell projection

A prolongation or process extending from a cell and that is bounded by plasma membrane, e.g. a cilium, lamellipodium, or axon.

Type
:
structural_complex
Taxonomic scope
:
conserved biosystem
BSID:
1510198
GO
: GO:0120025
2.

positive regulation of lipid localization

Any process that activates or increases the frequency, rate or extent of lipid localization. Synonyms: activation of lipid localisation; activation of lipid localization; positive regulation of lipid localisation; up regulation of lipid localisation; up regulation of lipid localization;...

Type
:
pathway
Taxonomic scope
:
conserved biosystem
BSID:
1495433
GO
: GO:1905954
3.

regulation of lipid localization

Any process that modulates the frequency, rate or extent of lipid localization. Synonym: regulation of lipid localisation;

Type
:
pathway
Taxonomic scope
:
conserved biosystem
BSID:
1495431
GO
: GO:1905952
4.

neuron to neuron synapse

A synapse in which pre and post-synaptic cells are neurons.

Type
:
structural_complex
Taxonomic scope
:
conserved biosystem
BSID:
1427935
GO
: GO:0098984
5.

vesicle-mediated transport to the plasma membrane

The directed movement of substances to the plasma membrane in transport vesicles that fuse with the plasma membrane by exocytosis.

Type
:
pathway
Taxonomic scope
:
conserved biosystem
BSID:
1400652
GO
: GO:0098876
6.

intracellular vesicle

Any vesicle that is part of the intracellular region.

Type
:
structural_complex
Taxonomic scope
:
conserved biosystem
BSID:
1384516
GO
: GO:0097708
7.

transmembrane receptor activity

Combining with an extracellular or intracellular signal and transmitting a signal from one side of the membrane to the other.

Type
:
functional_set
Taxonomic scope
:
conserved biosystem
BSID:
1353948
GO
: GO:0099600
8.

postsynaptic specialization

A network of proteins within and adjacent to the postsynaptic membrane. Its major components include neurotransmitter receptors and the proteins that spatially and functionally organize them such as anchoring and scaffolding molecules, signaling enzymes and cytoskeletal component...

Type
:
structural_complex
Taxonomic scope
:
conserved biosystem
BSID:
1347044
GO
: GO:0099572
9.

membrane microdomain

A membrane region with a lipid composition that is distinct from that of the membrane regions that surround it.

Type
:
structural_complex
Taxonomic scope
:
conserved biosystem
BSID:
1311006
GO
: GO:0098857
10.

protein localization to cell periphery

A process in which a protein is transported to, or maintained in, the cell periphery.

Type
:
pathway
Taxonomic scope
:
conserved biosystem
BSID:
1272459
GO
: GO:1990778
11.

whole membrane

Any lipid bilayer that completely encloses some structure, and all the proteins embedded in it or attached to it. Examples include the plasma membrane and most organelle membranes.

Type
:
structural_complex
Taxonomic scope
:
conserved biosystem
BSID:
1272078
GO
: GO:0098805
12.

postsynapse

The part of a synapse that is part of the post-synaptic cell.

Type
:
structural_complex
Taxonomic scope
:
conserved biosystem
BSID:
1272068
GO
: GO:0098794
13.

Activation of SMO

Activation of the transmembrane protein SMO in response to Hh stimulation is a major control point in the Hh signaling pathway (reviewed in Ayers and Therond, 2010; Jiang and Hui, 2008). In the absence of ligand, SMO is inhibited in an unknown manner by the Hh receptor PTCH. PTCH...

Type
:
pathway
Taxonomic scope
:
organism-specific biosystem
Organism
:
Homo sapiens
14.

Ligand-receptor interactions

Repression of Hh signaling in the absence of ligand depends on the transmembrane receptor protein Patched (PTCH), which inhibits Smoothened (SMO) activity by an unknown mechanism. This promotes the proteolytic processing and/or degradation of the GLI family of transcription factors...

Type
:
pathway
Taxonomic scope
:
organism-specific biosystem
Organism
:
Homo sapiens
15.

Hedgehog 'on' state

Hedgehog is a secreted morphogen that has evolutionarily conserved roles in body organization by regulating the activity of the Ci/Gli transcription factor family. In Drosophila in the absence of Hh signaling, full-length Ci is partially degraded by the proteasome to generate a truncated...

Type
:
pathway
Taxonomic scope
:
organism-specific biosystem
Organism
:
Homo sapiens
16.

Hedgehog 'off' state

Hedgehog is a secreted morphogen that has evolutionarily conserved roles in body organization by regulating the activity of the Ci/Gli transcription factor family. In Drosophila in the absence of Hh signaling, full-length Ci is partially degraded by the proteasome to generate a truncated...

Type
:
pathway
Taxonomic scope
:
organism-specific biosystem
Organism
:
Homo sapiens
17.

Signaling by Hedgehog

Hedgehog (Hh) is a secreted morphogen that regulates developmental processes in vertebrates including limb bud formation, neural tube patterning, cell growth and differentiation (reviewed in Hui and Angers, 2011). Hh signaling also contributes to stem cell homeostasis in adult tissues....

Type
:
pathway
Taxonomic scope
:
organism-specific biosystem
Organism
:
Homo sapiens
18.

Class B/2 (Secretin family receptors)

This family is known as Family B (secretin-receptor family, family 2) G-protein-coupled receptors. Family B GPCRs include secretin, calcitonin, parathyroid hormone/parathyroid hormone-related peptides and vasoactive intestinal peptide receptors; all of which activate adenylyl cyclase...

Type
:
pathway
Taxonomic scope
:
organism-specific biosystem
Organism
:
Homo sapiens
19.

GPCR ligand binding

There are more than 800 G-protein coupled receptor (GPCRs) in the human genome, making it the largest receptor superfamily. GPCRs are also the largest class of drug targets, involved in virtually all physiological processes (Frederiksson 2003). GPCRs are receptors for a diverse range...

Type
:
pathway
Taxonomic scope
:
organism-specific biosystem
Organism
:
Homo sapiens
20.

Signaling by GPCR

G protein-coupled receptors (GPCRs; 7TM receptors; seven transmembrane domain receptors; heptahelical receptors; G protein-linked receptors [GPLR]) are the largest family of transmembrane receptors in humans, accounting for more than 1% of the protein-coding capacity of the human...

Type
:
pathway
Taxonomic scope
:
organism-specific biosystem
Organism
:
Homo sapiens

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