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Links from Nucleotide

Items: 1 to 20 of 258

1.

RNA polymerase II C-terminal domain binding

Interacting selectively and non-covalently with the C-terminal domain (CTD) of the largest subunit of RNA polymerase II. The CTD is comprised of repeats of a heptapeptide with the consensus sequence YSPTSPS. The number of repeats varies with the species and a minimum number of repeats...

Type
:
functional_set
Taxonomic scope
:
conserved biosystem
BSID:
1471254
GO
: GO:0099122
2.

E3 ubiquitin ligases ubiquitinate target proteins

E3 ubiquitin ligases catalyze the transfer of an ubiquitin from an E2-ubiquitin conjugate to a target protein. Generally, ubiquitin is transferred via formation of an amide bond to a particular lysine residue of the target protein, but ubiquitylation of cysteine, serine and threonine...

Type
:
pathway
Taxonomic scope
:
organism-specific biosystem
Organism
:
Homo sapiens
3.

Endoderm Differentiation

Model depicting endoderm specification based on the literature and highly enriched gene expression profiles via comparison across dozens of independent induced and embryonic pluripotent stem cell lines, following differentiation to multiple lineages (ectoderm, mesoderm, endoderm,...

Type
:
pathway
Taxonomic scope
:
organism-specific biosystem
4.

Protein ubiquitination

Ubiquitin is a small, 76 amino acid residue protein that is conjugated by E3 ubiquitin ligases to other proteins in order to regulate their function or degradation (enzymatic cascade reviewed in Neutzner and Neutzner 2012, Kleiger and Mayor 2014, structures and mechanisms of conjugating...

Type
:
pathway
Taxonomic scope
:
organism-specific biosystem
Organism
:
Homo sapiens
5.

positive regulation of chromatin organization

Any process that activates or increases the frequency, rate or extent of chromatin organization. Synonyms: GO:1903310; activation of chromatin organisation; activation of chromatin organization; activation of establishment or maintenance of chromatin architecture; positive regulation...

Type
:
pathway
Taxonomic scope
:
conserved biosystem
BSID:
1428069
GO
: GO:1905269
6.

cell-cell signaling by wnt

Any process that mediates the transfer of information from one cell to another, medaited by a wnt family protein ligand. This process includes wnt signal transduction in the receiving cell, release of wnt ligand from a secreting cell as well as any processes that actively facilitate...

Type
:
pathway
Taxonomic scope
:
conserved biosystem
BSID:
1400661
GO
: GO:0198738
7.

cell surface receptor signaling pathway involved in cell-cell signaling

Any cell surface receptor signaling pathway that is involved in cell-cell signaling. Synonyms: cell surface receptor linked signal transduction involved in cell-cell signaling; cell surface receptor linked signal transduction involved in cell-cell signalling; cell surface receptor...

Type
:
pathway
Taxonomic scope
:
conserved biosystem
BSID:
1384661
GO
: GO:1905114
8.

transferase complex, transferring phosphorus-containing groups

A transferase complex capable of catalysis of the transfer of a phosphorus-containing group from one compound (donor) to another (acceptor).

Type
:
structural_complex
Taxonomic scope
:
conserved biosystem
BSID:
1272014
GO
: GO:0061695
9.

Formation of RNA Pol II elongation complex

TFIIS is a transcription factor involved in different phases of transcription, occurring in a major ubiquitous form and other tissue specific forms. TFIIS stimulates RNA Pol II complex out of elongation arrest. Other transcription factors like ELL, Elongin family members and TFIIF...

Type
:
pathway
Taxonomic scope
:
organism-specific biosystem
Organism
:
Homo sapiens
10.

RNA Polymerase II Transcription Elongation

The mechanisms governing the process of elongation during eukaryotic mRNA synthesis are being unraveled by recent studies. These studies have led to the expected discovery of a diverse collection of transcription factors that directly regulate the activities of RNA Polymerase II and...

Type
:
pathway
Taxonomic scope
:
organism-specific biosystem
Organism
:
Homo sapiens
11.

RNA Polymerase II Pre-transcription Events

Type
:
pathway
Taxonomic scope
:
organism-specific biosystem
Organism
:
Homo sapiens
12.

RNA Polymerase II Transcription

Type
:
pathway
Taxonomic scope
:
organism-specific biosystem
Organism
:
Homo sapiens
13.

Gene Expression

Gene Expression covers the pathways by which genomic DNA is transcribed to yield RNA, the regulation of these transcription processes, and the pathways by which newly-made RNA Transcripts are processed. Most annotation is centered on the generation of messenger RNAs (mRNAs) by regulated...

Type
:
pathway
Taxonomic scope
:
organism-specific biosystem
Organism
:
Homo sapiens
14.

Post-translational protein modification

After translation, many newly formed proteins undergo further covalent modifications that alter their functional properties and that are essentially irreversible under physiological conditions in the body. These modifications include the internal peptide bond cleavages that activate...

Type
:
pathway
Taxonomic scope
:
organism-specific biosystem
Organism
:
Homo sapiens
15.

Metabolism of proteins

Protein metabolism comprises the pathways of translation, post-translational modification and protein folding.

Type
:
pathway
Taxonomic scope
:
organism-specific biosystem
Organism
:
Homo sapiens
16.

positive regulation of nucleic acid-templated transcription

Any process that activates or increases the frequency, rate or extent of nucleic acid-templated transcription. Synonyms: activation of nucleic acid-templated transcription; up regulation of nucleic acid-templated transcription; up-regulation of nucleic acid-templated transcription;...

Type
:
pathway
Taxonomic scope
:
conserved biosystem
BSID:
1129335
GO
: GO:1903508
17.

negative regulation of nucleic acid-templated transcription

Any process that stops, prevents or reduces the frequency, rate or extent of nucleic acid-templated transcription. Synonyms: down regulation of nucleic acid-templated transcription; down-regulation of nucleic acid-templated transcription; downregulation of nucleic acid-templated transcription;...

Type
:
pathway
Taxonomic scope
:
conserved biosystem
BSID:
1129334
GO
: GO:1903507
18.

regulation of nucleic acid-templated transcription

Any process that modulates the frequency, rate or extent of nucleic acid-templated transcription.

Type
:
pathway
Taxonomic scope
:
conserved biosystem
BSID:
1129333
GO
: GO:1903506
19.

nucleic acid-templated transcription

The cellular synthesis of RNA on a template of nucleic acid (DNA or RNA).

Type
:
pathway
Taxonomic scope
:
conserved biosystem
BSID:
1129277
GO
: GO:0097659
20.

macromolecular complex binding

Interacting selectively and non-covalently with any macromolecular complex.

Type
:
functional_set
Taxonomic scope
:
conserved biosystem
BSID:
1129214
GO
: GO:0044877

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