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Select item 79817821.

Conditional Silencing of H-2D^b Class I Molecule Expression Modulates the Protective and Pathogenic Kinetics of Virus-Antigen–Specific CD8 T Cell Responses during Theiler’s Virus Infection

Zachariah P. Tritz, Robin C. Orozco, Courtney S. Malo, Katayoun Ayasoufi, Cori E. Fain, Roman H. Khadka, Emma N. Goddery, Lila T. Yokanovich, Megan L. Settell, Michael J. Hansen, Fang Jin, Kevin D. Pavelko, Larry R. Pease, Aaron J. Johnson

J Immunol. Author manuscript; available in PMC 2021 Sep 1.

Published in final edited form as: J Immunol. 2020 Sep 1; 205(5): 1228–1238. Published online 2020 Jul 31. doi: 10.4049/jimmunol.2000340

PMCID:: PMC7981782

Abstract Article PDF–1.7M

Select item 77531202.

Glioblastoma Organoids: Pre-Clinical Applications and Challenges in the Context of Immunotherapy

Eliane Klein, Ann-Christin Hau, Anaïs Oudin, Anna Golebiewska, Simone P. Niclou

Front Oncol. 2020; 10: 604121. Published online 2020 Dec 8. doi: 10.3389/fonc.2020.604121

PMCID:: PMC7753120

Abstract Article PDF–963K

Select item 76729953.

Phase II study of tivozanib, an oral VEGFR inhibitor, in patients with recurrent glioblastoma

Jayashree Kalpathy-Cramer, Vyshak Chandra, Xiao Da, Yangming Ou, Kyrre E. Emblem, Alona Muzikansky, Xuezhu Cai, Linda Douw, John G. Evans, Jorg Dietrich, Andrew S. Chi, Patrick Y. Wen, Stephen Stufflebeam, Bruce Rosen, Dan G. Duda, Rakesh K. Jain, Tracy T. Batchelor, Elizabeth R. Gerstner

J Neurooncol. Author manuscript; available in PMC 2020 Nov 18.

Published in final edited form as: J Neurooncol. 2017 Feb; 131(3): 603–610. Published online 2016 Nov 16. doi: 10.1007/s11060-016-2332-5

PMCID:: PMC7672995

Abstract Article PDF–333K

Select item 73791314.

Molecular Heterogeneity and Immunosuppressive Microenvironment in Glioblastoma

Syreeta DeCordova, Abhishek Shastri, Anthony G. Tsolaki, Hadida Yasmin, Lukas Klein, Shiv K. Singh, Uday Kishore

Front Immunol. 2020; 11: 1402. Published online 2020 Jul 17. doi: 10.3389/fimmu.2020.01402

PMCID:: PMC7379131

Abstract Article PDF–1.3M

Select item 72654135.

Humanized immune system mouse models: progress, challenges and opportunities

Todd M. Allen, Michael A. Brehm, Sandra Bridges, Stacy Ferguson, Priti Kumar, Oleg Mirochnitchenko, Karolina Palucka, Roberta Pelanda, Brigitte Sanders-Beer, Leonard D. Shultz, Lishan Su, Mercy PrabhuDas

Nat Immunol. Author manuscript; available in PMC 2020 Jun 2.

Published in final edited form as: Nat Immunol. 2019 Jul; 20(7): 770–774. doi: 10.1038/s41590-019-0416-z

PMCID:: PMC7265413

Abstract Article PDF–868K

Select item 72138626.

An improved patient-derived xenograft humanized mouse model for evaluation of lung cancer immune responses

Ismail M Meraz, Mourad Majidi, Feng Meng, RuPing Shao, Min Jin Ha, Shinya Neri, Bingliang Fang, Steven H Lin, Peggy T Tinkey, Elizabeth J Shpall, Jeffrey Morris, Jack A Roth

Cancer Immunol Res. Author manuscript; available in PMC 2020 May 11.

Published in final edited form as: Cancer Immunol Res. 2019 Aug; 7(8): 1267–1279. Published online 2019 Jun 11. doi: 10.1158/2326-6066.CIR-18-0874

PMCID:: PMC7213862

Abstract Article PDF–2.9M

Select item 70005177.

Tamoxifen-independent recombination of reporter genes limits lineage tracing and mosaic analysis using CreER^T2 lines

A. Álvarez-Aznar, I. Martínez-Corral, N. Daubel, C. Betsholtz, T. Mäkinen, K. Gaengel

Transgenic Res. 2020; 29(1): 53–68. Published online 2019 Oct 22. doi: 10.1007/s11248-019-00177-8

PMCID:: PMC7000517

Abstract Article PDF–7.0M

Select item 69578748.

A Xenotransplant Model of Human Brain Tumors in Wild-Type Mice

Nadin Hoffmann, Virginia Fernández, Rui Cruz Pereira, Silvia Rancati, Roberta Pelizzoli, Davide De Pietri Tonelli

iScience. 2020 Jan 24; 23(1): 100813. Published online 2019 Dec 30. doi: 10.1016/j.isci.2019.100813

PMCID:: PMC6957874

Abstract Article PDF–11M

Select item 69025229.

Immune landscapes associated with different glioblastoma molecular subtypes

Maria Martinez-Lage, Timothy M. Lynch, Yingtao Bi, Carolina Cocito, Gregory P. Way, Sharmistha Pal, Josephine Haller, Rachel E. Yan, Amy Ziober, Aivi Nguyen, Manoj Kandpal, Donald M. O’Rourke, Jeffrey P. Greenfield, Casey S. Greene, Ramana V. Davuluri, Nadia Dahmane

Acta Neuropathol Commun. 2019; 7: 203. Published online 2019 Nov 29. doi: 10.1186/s40478-019-0803-6

PMCID:: PMC6902522

Abstract Article PDF–3.7M

Select item 677736810.

CT-2A neurospheres-derived high-grade glioma in mice: a new model to address tumor stem cells and immunosuppression

Matteo Riva, Roxanne Wouters, Akila Weerasekera, Sarah Belderbos, David Nittner, Dietmar R. Thal, Thaïs Baert, Roberto Giovannoni, Willy Gsell, Uwe Himmelreich, Marc Van Ranst, An Coosemans

Biol Open. 2019 Sep 15; 8(9): bio044552. Published online 2019 Sep 11. doi: 10.1242/bio.044552

PMCID:: PMC6777368

Abstract Article PDF–2.2M

Select item 677067311.

Genetically Engineered Mouse Models of Gliomas: Technological Developments for Translational Discoveries

Imran Noorani

Cancers (Basel) 2019 Sep; 11(9): 1335. Published online 2019 Sep 9. doi: 10.3390/cancers11091335

PMCID:: PMC6770673

Abstract Article PDF–1.4M

Select item 676519012.

Experimental models and tools to tackle glioblastoma

Faye L. Robertson, Maria-Angeles Marqués-Torrejón, Gillian M. Morrison, Steven M. Pollard

Dis Model Mech. 2019 Sep 1; 12(9): dmm040386. Published online 2019 Sep 6. doi: 10.1242/dmm.040386

PMCID:: PMC6765190

Abstract Article

Select item 672163713.

Application of Highly Immunocompromised Mice for the Establishment of Patient-Derived Xenograft (PDX) Models

Seiji Okada, Kulthida Vaeteewoottacharn, Ryusho Kariya

Cells. 2019 Aug; 8(8): 889. Published online 2019 Aug 13. doi: 10.3390/cells8080889

PMCID:: PMC6721637

Abstract Article PDF–2.6M

Select item 648784614.

The latest animal models of ovarian cancer for novel drug discovery

Elizabeth Magnotti, Wayne A. Marasco

Expert Opin Drug Discov. Author manuscript; available in PMC 2019 Apr 29.

Published in final edited form as: Expert Opin Drug Discov. 2018 Mar; 13(3): 249–257. Published online 2018 Jan 17. doi: 10.1080/17460441.2018.1426567

PMCID:: PMC6487846

Abstract Article PDF–776K

Select item 644509915.

Insertional mutagenesis using the Sleeping Beauty transposon system identifies drivers of erythroleukemia in mice

Keith R. Loeb, Bridget T. Hughes, Brian M. Fissel, Nyka J. Osteen, Sue E. Knoblaugh, Jonathan E. Grim, Luke J. Drury, Aaron Sarver, Adam J. Dupuy, Bruce E. Clurman

Sci Rep. 2019; 9: 5488. Published online 2019 Apr 2. doi: 10.1038/s41598-019-41805-x

PMCID:: PMC6445099

Abstract Article PDF–4.3M

Select item 635681216.

Glioblastoma’s Next Top Model: Novel Culture Systems for Brain Cancer Radiotherapy Research

Seamus Caragher, Anthony J. Chalmers, Natividad Gomez-Roman

Cancers (Basel) 2019 Jan; 11(1): 44. Published online 2019 Jan 4. doi: 10.3390/cancers11010044

PMCID:: PMC6356812

Abstract Article PDF–1.4M

Select item 633361117.

Mouse Cre-LoxP system: general principles to determine tissue-specific roles of target genes

Hyeonhui Kim, Minki Kim, Sun-Kyoung Im, Sungsoon Fang

Lab Anim Res. 2018 Dec; 34(4): 147–159. Published online 2018 Dec 31. doi: 10.5625/lar.2018.34.4.147

PMCID:: PMC6333611

Abstract Article PDF–1.8M

Select item 615010918.

Temozolomide resistance in glioblastoma multiforme

Sang Y. Lee

Genes Dis. 2016 Sep; 3(3): 198–210. Published online 2016 May 11. doi: 10.1016/j.gendis.2016.04.007

PMCID:: PMC6150109

Abstract Article PDF–385K

Select item 612465519.

Immunomodulation Mediated by Anti-angiogenic Therapy Improves CD8 T Cell Immunity Against Experimental Glioma

Courtney S. Malo, Roman H. Khadka, Katayoun Ayasoufi, Fang Jin, Jackson E. AbouChehade, Michael J. Hansen, Raymond Iezzi, Kevin D. Pavelko, Aaron J. Johnson

Front Oncol. 2018; 8: 320. Published online 2018 Aug 20. doi: 10.3389/fonc.2018.00320

PMCID:: PMC6124655

Abstract Article PDF–962K

Select item 608285720.

Studying cancer immunotherapy using patient-derived xenografts (PDXs) in humanized mice

Yunsik Choi, Sanghyuk Lee, Kapyoul Kim, Soo-Hyun Kim, Yeun-Jun Chung, Charles Lee

Exp Mol Med. 2018 Aug; 50(8): 99. Published online 2018 Aug 7. doi: 10.1038/s12276-018-0115-0

PMCID:: PMC6082857

Abstract Article PDF–980K

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