PMC Links for Books (Select 2975990) - PMC

Select item 74262421.

Combining Clinical and Candidate Gene Data into a Risk Score for Azathioprine-Associated Leukopenia in Routine Clinical Practice

Prathima Anandi, Alyson L. Dickson, QiPing Feng, Wei-Qi Wei, William D. Dupont, Dale Plummer, Ge Liu, Rany Octaria, Katherine A. Barker, Vivian K. Kawai, Kelly Birdwell, Nancy J. Cox, Adriana Hung, C. Michael Stein, Cecilia P. Chung

Pharmacogenomics J. Author manuscript; available in PMC 2020 Sep 23.

Published in final edited form as: Pharmacogenomics J. 2020 Oct; 20(5): 736–745. Published online 2020 Feb 14. doi: 10.1038/s41397-020-0163-4

PMCID:: PMC7426242

Article PDF–824K

Select item 73855792.

NUDT15 gene variants and thiopurine-induced leukopenia in patients with inflammatory bowel disease

Katsuyoshi Matsuoka

Intest Res. 2020 Jul; 18(3): 275–281. Published online 2020 Jun 3. doi: 10.5217/ir.2020.00002

PMCID:: PMC7385579

Article PDF–733K

Select item 70901033.

Predictive Value of NUDT15 Variants on Neutropenia Among Han Chinese Patients with Dermatologic Diseases: A Single-Center Observational Study

Po-Wei Huang, Yu-Hsian Tseng, Tsen-Fang Tsai

Dermatol Ther (Heidelb) 2020 Apr; 10(2): 263–271. Published online 2020 Feb 15. doi: 10.1007/s13555-020-00360-4

PMCID:: PMC7090103

Article PDF–309K

Select item 66886234.

Application of Economic Evaluation to Assess Feasibility for Reimbursement of Genomic Testing as Part of Personalized Medicine Interventions

Stavros Simeonidis, Stefania Koutsilieri, Athanassios Vozikis, David N. Cooper, Christina Mitropoulou, George P. Patrinos

Front Pharmacol. 2019; 10: 830. Published online 2019 Aug 2. doi: 10.3389/fphar.2019.00830

PMCID:: PMC6688623

Article PDF–2.6M

Select item 65762675.

Clinical Pharmacogenetics Implementation Consortium (CPIC) guideline for thiopurine dosing based on TPMT and NUDT15 genotypes: 2018 update

Mary V. Relling, Matthias Schwab, Michelle Whirl-Carrillo, Guilherme Suarez-Kurtz, Ching-Hon Pui, Charles M. Stein, Ann M. Moyer, William E. Evans, Teri E. Klein, Federico Guillermo Antillon-Klussmann, Kelly E. Caudle, Motohiro Kato, Allen EJ Yeoh, Kjeld Schmiegelow, Jun J. Yang

Clin Pharmacol Ther. Author manuscript; available in PMC 2020 May 1.

Published in final edited form as: Clin Pharmacol Ther. 2019 May; 105(5): 1095–1105. Published online 2019 Jan 20. doi: 10.1002/cpt.1304

PMCID:: PMC6576267

Article PDF–774K

Select item 52926796.

Prediction of CYP2D6 phenotype from genotype across world populations

Andrea Gaedigk, Katrin Sangkuhl, Michelle Whirl-Carrillo, Teri Klein, J. Steven Leeder

Genet Med. 2017 Jan; 19(1): 69–76. Published online 2016 Jul 7. doi: 10.1038/gim.2016.80

Correction in:: Genet Med. 2016; 18(11): 1167.

PMCID:: PMC5292679

Article PDF–1.2M

Select item 50955717.

How I treat my inflammatory bowel disease-patients with thiopurines?

Berrie Meijer, Chris JJ Mulder, Adriaan A van Bodegraven, Nanne K H de Boer

World J Gastrointest Pharmacol Ther. 2016 Nov 6; 7(4): 524–530. Published online 2016 Nov 6. doi: 10.4292/wjgpt.v7.i4.524

PMCID:: PMC5095571

Article PDF–979K

Select item 49993378.

A common missense variant in NUDT15 confers susceptibility to thiopurine-induced leukopenia

Suk-Kyun Yang, Myunghee Hong, Jiwon Baek, Hyunchul Choi, Wanting Zhao, Yusun Jung, Talin Haritunians, Byong Duk Ye, Kyung-Jo Kim, Sang Hyoung Park, Soo-Kyung Park, Dong-Hoon Yang, Marla Dubinsky, Inchul Lee, Dermot P B McGovern, Jianjun Liu, Kyuyoung Song

Nat Genet. Author manuscript; available in PMC 2016 Aug 25.

Published in final edited form as: Nat Genet. 2014 Sep; 46(9): 1017–1020. Published online 2014 Aug 10. doi: 10.1038/ng.3060

PMCID:: PMC4999337

Article PDF–457K

Select item 47371079.

Thiopurine dose intensity and treatment outcome in childhood lymphoblastic leukaemia: the influence of thiopurine methyltransferase pharmacogenetics

Lynne Lennard, Cher S. Cartwright, Rachel Wade, Ajay Vora

Br J Haematol. 2015 Apr; 169(2): 228–240. Published online 2014 Nov 29. doi: 10.1111/bjh.13240

PMCID:: PMC4737107

Article PDF–198K

Select item 441696910.

Optimizing the use of thiopurines in inflammatory bowel disease

Rishi M. Goel, Paul Blaker, Alex Mentzer, Steven C.M. Fong, Anthony M. Marinaki, Jeremy D. Sanderson

Ther Adv Chronic Dis. 2015 May; 6(3): 138–146. doi: 10.1177/2040622315579063

PMCID:: PMC4416969

Article PDF–808K

Select item 437530411.

Inherited NUDT15 Variant Is a Genetic Determinant of Mercaptopurine Intolerance in Children With Acute Lymphoblastic Leukemia

Jun J. Yang, Wendy Landier, Wenjian Yang, Chengcheng Liu, Lindsey Hageman, Cheng Cheng, Deqing Pei, Yanjun Chen, Kristine R. Crews, Nancy Kornegay, F. Lennie Wong, William E. Evans, Ching-Hon Pui, Smita Bhatia, Mary V. Relling

J Clin Oncol. 2015 Apr 10; 33(11): 1235–1242. Published online 2015 Jan 26. doi: 10.1200/JCO.2014.59.4671

PMCID:: PMC4375304

Article PDF–594K

Select item 437063212.

Association between Thiopurine S-methyltransferase Polymorphisms and Thiopurine-Induced Adverse Drug Reactions in Patients with Inflammatory Bowel Disease: A Meta-Analysis

Yue-Ping Liu, Hai-Yan Wu, Xiang Yang, Han-Qing Xu, Yong-Chuan Li, Da-Chuan Shi, Jun-Fu Huang, Qing Huang, Wei-Ling Fu

PLoS One. 2015; 10(3): e0121745. Published online 2015 Mar 23. doi: 10.1371/journal.pone.0121745

PMCID:: PMC4370632

Article PDF–1.7M

Select item 424389813.

Thiopurine monitoring in children with inflammatory bowel disease: a systematic review

Anastasia Konidari, Antonios Anagnostopoulos, Laura J Bonnett, Munir Pirmohamed, Wael El-Matary

Br J Clin Pharmacol. 2014 Sep; 78(3): 467–476. Published online 2014 Aug 21. doi: 10.1111/bcp.12365

PMCID:: PMC4243898

Article PDF–757K

Select item 402796614.

Thiopurine pharmacogenomics: association of SNPs with clinical response and functional validation of candidate genes

Alice Matimba, Fang Li, Alina Livshits, Cher S Cartwright, Stephen Scully, Brooke L Fridley, Gregory Jenkins, Anthony Batzler, Liewei Wang, Richard Weinshilboum, Lynne Lennard

Pharmacogenomics. Author manuscript; available in PMC 2015 Mar 1.

Published in final edited form as: Pharmacogenomics. 2014 Mar; 15(4): 433–447. doi: 10.2217/pgs.13.226

PMCID:: PMC4027966

Article PDF–1.4M

Select item 372789315.

Nomenclature for alleles of the thiopurine methyltransferase gene

Malin L. Appell, Jonathan Berg, John Duley, William E. Evans, Martin A. Kennedy, Lynne Lennard, Tony Marinaki, Howard L. McLeod, Mary V. Relling, Elke Schaeffeler, Matthias Schwab, Richard Weinshilboum, Allen E.J. Yeoh, Ellen M. McDonagh, Joan M. Hebert, Teri E. Klein, Sally A. Coulthard

Pharmacogenet Genomics. Author manuscript; available in PMC 2014 Apr 1.

Published in final edited form as: Pharmacogenet Genomics. 2013 Apr; 23(4): 242–248. doi: 10.1097/FPC.0b013e32835f1cc0

PMCID:: PMC3727893

Article PDF–592K

Select item 370323516.

Thiopurine methyltransferase genotype–phenotype discordance and thiopurine active metabolite formation in childhood acute lymphoblastic leukaemia

Lynne Lennard, Cher Suzanne Cartwright, Rachel Wade, Susan M Richards, Ajay Vora

Br J Clin Pharmacol. 2013 Jul; 76(1): 125–136. Published online 2012 Dec 18. doi: 10.1111/bcp.12066

PMCID:: PMC3703235

Article PDF–1.3M

Select item 360464317.

Clinical Pharmacogenetics Implementation Consortium Guidelines for Thiopurine Methyltransferase Genotype and Thiopurine Dosing: 2013 Update

M V Relling, E E Gardner, W J Sandborn, K Schmiegelow, C-H Pui, S W Yee, C M Stein, M Carrillo, W E Evans, J K Hicks, M Schwab, T E Klein

Clin Pharmacol Ther. 2013 Apr; 93(4): 324–325. Prepublished online 2013 Jan 17. Published online 2013 Feb 20. doi: 10.1038/clpt.2013.4

PMCID:: PMC3604643

Article PDF–384K

Select item 309876118.

Clinical Pharmacogenetics Implementation Consortium Guidelines for Thiopurine Methyltransferase Genotype and Thiopurine Dosing

MV Relling, EE Gardner, WJ Sandborn, K Schmiegelow, C-H Pui, SW Yee, CM Stein, M Carrillo, WE Evans, TE Klein

Clin Pharmacol Ther. 2011 Mar; 89(3): 387–391. Published online 2011 Jan 26. doi: 10.1038/clpt.2010.320

Correction in:: Clin Pharmacol Ther. 2011 Dec; 90(6): 894.

PMCID:: PMC3098761

Article PDF–131K

Select item 308684019.

Very important pharmacogene summary: thiopurine S-methyltransferase

Liewei Wang, Linda Pelleymounter, Richard Weinshilboum, Julie A. Johnson, Joan M. Hebert, Russ B. Altman, Teri E. Klein

Pharmacogenet Genomics. Author manuscript; available in PMC 2011 Jun 1.

Published in final edited form as: Pharmacogenet Genomics. 2010 Jun; 20(6): 401–405. doi: 10.1097/FPC.0b013e3283352860

PMCID:: PMC3086840

Article PDF–288K

Select item 191468920.

Thiopurine S-methyltransferase deficiency: two nucleotide transitions define the most prevalent mutant allele associated with loss of catalytic activity in Caucasians.

H. L. Tai, E. Y. Krynetski, C. R. Yates, T. Loennechen, M. Y. Fessing, N. F. Krynetskaia, W. E. Evans

Am J Hum Genet. 1996 Apr; 58(4): 694–702.

PMCID:: PMC1914689

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