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Figure 2. Structure of the UGT2B17 region on chromosome 4 in build 36 and the GRCh37 build (build 37) as demonstrated by Map Viewer displays of human genome BLAST results.

Figure 2Structure of the UGT2B17 region on chromosome 4 in build 36 and the GRCh37 build (build 37) as demonstrated by Map Viewer displays of human genome BLAST results

Top panel, left. Human genome BLAST search set-up from the “Views and Tools” feature on the TMPRSS11E gene in the graphical viewer. Top panel, right. Human genome BLAST results, build 36, highlighting (red) the apparent duplication of the TMPRSS11E gene. The UGT2B17 gene (black arrow) is on the contig above the gap in the assembly. Bottom panel, left. TMPRSS11E BLAST results on the primary reference assembly showing the single result and the UGTB17 gene. Bottom panel, left. BLAST results on the alternate locus for the UGT2B17 null allele. The apparent duplication and gap are resolved in GRCh37.

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