U.S. flag

An official website of the United States government

NCBI Bookshelf. A service of the National Library of Medicine, National Institutes of Health.

Michael AC, Borland LM, editors. Electrochemical Methods for Neuroscience. Boca Raton (FL): CRC Press/Taylor & Francis; 2007.

Cover of Electrochemical Methods for Neuroscience

Electrochemical Methods for Neuroscience.

Show details


Adrian C. Michael and Laura M. Borland.

Electrochemical methods of analysis are more frequently playing a central role in achieving one of the prime objectives of neuroscience research, the understanding of the role of specific neurotransmitters in normal brain function and the pathophysiology of central nervous system disorders. About thirty five years ago, Ralph N. Adams at the University of Kansas took the first step of implanting a carbon microelectrode into the brain of a rat in an effort to measure the extracellular concentration of catecholamine neurotransmitters. Subsequent years were spent sorting out the meanings of electrochemical responses observed under various experimental conditions and reliable identification of what was being detected was accomplished by the time that Jay Justice summarized the field in his 1987 volume Voltammetry in the Neurosciences. Technical progress continued through the 1990s to this day, leading to advances in the contribution of electrochemical methods to the understanding of brain function. The efforts of numerous research groups, many represented in the chapters of this book, have enhanced the sensitivity, selectivity and spatiotemporal resolution of electrochemical techniques to the point that they now provide information that is not accessible by any other means. The objective of this book is to provide the interested reader with an updated summary of the present, albeit still evolving, state of the art and to establish the basis upon which to reach sound decisions about incorporating electrochemical techniques into ongoing or newly emerging research programs in the neuroscience disciplines.

We are indebted to many individuals without whom this volume would not have reached fruition. We are certainly grateful to the series editors, Sid Simon and Miguel Nicolelis, for encouraging us to embark upon this project. Sid’s enthusiasm is unrelenting, to say the least! We are also grateful to Barbara Norwitz and Jill Jurgensen of Taylor & Francis for their assistance, encouragement, and patience. Finally, it goes without saying that this volume would not have been completed were it not for the willing efforts of the contributing authors. We apologize to the numerous groups making invaluable contributions to the field whom we were unable to invite to contribute a chapter. It was not our objective to cover the field exhaustively, but rather to provide a sampling that would introduce and orient the newcomer to the fundamental aspects and applications of electrochemistry in the neurosciences.

Copyright © 2007, Taylor & Francis Group, LLC.
Bookshelf ID: NBK2582


  • PubReader
  • Print View
  • Cite this Page

Other titles in this collection

Recent Activity

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

See more...