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SH2_SHC: Src homology 2 (SH2) domain found in SH2 adaptor protein C (SHC)
SHC is involved in a wide variety of pathways including regulating proliferation, angiogenesis, inva...
View in Cn3D Specific ProteinProteinSuperfamilySuperfamily MembersPubMed
iSH2_PIK3R1: Inter-Src homology 2 (iSH2) helical domain of Class IA Phosphoinositide 3-kinase Regulatory subunit 1, PIK3R1, also called p85alpha
PI3Ks catalyze the transfer of the gamma-phosphoryl group from ATP to the 3-hydroxyl of the inositol...
SH2_nSH2_p85_like: N-terminal Src homology 2 (nSH2) domain found in p85
Phosphoinositide 3-kinases (PI3Ks) are essential for cell growth, migration, and survival. p110, the...
PTKc_FGFR4: Catalytic domain of the Protein Tyrosine Kinase, Fibroblast Growth Factor Receptor 4
PTKs catalyze the transfer of the gamma-phosphoryl group from ATP to tyrosine (tyr) residues in prot...
SH2_cSH2_p85_like: C-terminal Src homology 2 (cSH2) domain found in p85
H_N_K_Ras_like: Ras GTPase family containing H-Ras,N-Ras and K-Ras4A/4B
H-Ras/N-Ras/K-Ras subfamily. H-Ras, N-Ras, and K-Ras4A/4B are the prototypical members of the Ras fa...
SH3_PLCgamma1: Src homology 3 domain of Phospholipase C (PLC) gamma 1
PLCgamma1 is widely expressed and is essential in growth and development. It is activated by the Trk...
SH2_N-SH2_PLC_gamma_like: N-terminal Src homology 2 (N-SH2) domain in Phospholipase C gamma
Phospholipase C gamma is a signaling molecule that is recruited to the C-terminal tail of the recept...
SH2_C-SH2_PLC_gamma_like: C-terminal Src homology 2 (C-SH2) domain in Phospholipase C gamma
C2_PLC_like: C2 domain present in Phosphoinositide-specific phospholipases C (PLC)
PLCs are involved in the hydrolysis of phosphatidylinositol-4,5-bisphosphate (PIP2) to d-myo-inosito...
RhoGEF
Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) d...
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