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C2: C2 domain
The C2 domain was first identified in PKC. C2 domains fold into an 8-standed beta-sandwich that can ...
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View in Cn3D Specific ProteinProteinSuperfamilySuperfamily MembersPubMed
PI3K_C2: Phosphoinositide 3-kinase C2
Phosphoinositide 3-kinase region postulated to contain a C2 domain. Outlier of pfam00168 family.
C2: Protein kinase C conserved region 2 (CalB)
Ca2+-binding motif present in phospholipases, protein kinases C, and synaptotagmins (among others). ...
PI3K_C2: Phosphoinositide 3-kinase, region postulated to contain C2 domain
Outlier of C2 family.
YPK1_N_like: Fungal protein kinase domain similar to the N-terminus of YPK1
This fungal domain family includes the N-terminal region of the Saccharomyces cerevisiae AGC kinases...
C2_Dock-D: C2 domains found in Dedicator Of CytoKinesis (Dock) class C proteins
Dock-D is one of 4 classes of Dock family proteins. The members here include: Dock9/Zizimin1, Dock1...
C2_Dock-C: C2 domains found in Dedicator Of CytoKinesis (Dock) class C proteins
Dock-C is one of 4 classes of Dock family proteins. The members here include: Dock6/Zir1, Dock7/Zir...
C2_Dock-B: C2 domains found in Dedicator Of CytoKinesis (Dock) class B proteins
Dock-B is one of 4 classes of Dock family proteins. The members here include: Dock3/MOCA (modifier ...
C2_Dock-A: C2 domains found in Dedicator Of CytoKinesis (Dock) class A proteins
Dock-A is one of 4 classes of Dock family proteins. The members here include: Dock180/Dock1, Dock2,...
C2_PI3K_class_I_beta_delta: C2 domain present in class I beta and delta phosphatidylinositol 3-kinases (PI3Ks)
PI3Ks (AKA phosphatidylinositol (PtdIns) 3-kinases) regulate cell processes such as cell growth, dif...
C2B_Tac2-N: C2 domain second repeat found in Tac2-N (Tandem C2 protein in Nucleus)
Tac2-N contains two C2 domains and a short C-terminus including a WHXL motif, which are key in stabi...
C2_NEDL1-like: C2 domain present in NEDL1 (NEDD4-like ubiquitin protein ligase-1)
NEDL1 (AKA HECW1(HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1)) is a newly ident...
C2_Freud-1: C2 domain found in 5' repressor element under dual repression binding protein-1 (Freud-1)
Freud-1 is a novel calcium-regulated repressor that negatively regulates basal 5-HT1A receptor expre...
C2_fungal_Pkc1p: C2 domain found in protein kinase C (Pkc1p) in Saccharomyces cerevisiae
This family is named after the protein kinase C in Saccharomyces cerevisiae, Pkc1p. Protein kinase C...
C2_KIAA0528-like: C2 domain found in the Human KIAA0528 cDNA clone
The members of this CD are named after the Human KIAA0528 cDNA clone. All members here contain a si...
C2_PKN-like: C2 domain in Protein kinase C-like (PKN) proteins
PKN is a lipid-activated serine/threonine kinase. It is a member of the protein kinase C (PKC) supe...
C2_ABR: C2 domain in the Active BCR (Breakpoint cluster region) Related protein
The ABR protein is similar to the breakpoint cluster region protein. It has homology to guanine nuc...
C2_RGS-like: C2 domain of the Regulator Of G-Protein Signaling (RGS) family
This CD contains members of the regulator of G-protein signaling (RGS) family. RGS is a GTPase activ...
C2A_Tac2-N: C2 domain first repeat found in Tac2-N (Tandem C2 protein in Nucleus)
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