Conserved Protein Domain Family
phosphohexomutase

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cl38939: phosphohexomutase Superfamily (this model, PSSM-Id:453899 is obsolete and has been replaced by 476822)
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The alpha-D-phosphohexomutase superfamily includes several related enzymes that catalyze a reversible intramolecular phosphoryl transfer on their sugar substrates. Members of this family include the phosphoglucomutases (PGM1 and PGM2), phosphoglucosamine mutase (PNGM), phosphoacetylglucosamine mutase (PAGM), the bacterial phosphomannomutase ManB, the bacterial phosphoglucosamine mutase GlmM, and the bifunctional phosphomannomutase/phosphoglucomutase (PMM/PGM). These enzymes play important and diverse roles in carbohydrate metabolism in organisms from bacteria to humans. Each of these enzymes has four domains with a centrally located active site formed by four loops, one from each domain. All four domains are included in this alignment model.
Statistics
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Accession: cl38939
PSSM Id: 453899
Name: phosphohexomutase
Created: 8-Jan-2020
Updated: 8-Mar-2022
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