Conserved Protein Domain Family
Uroplakin_II

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pfam07353: Uroplakin_II 
Uroplakin II
This family contains uroplakin II, which is approximately 180 residues long and seems to be restricted to mammals. Uroplakin II is an integral membrane protein, and is one of the components of the apical plaques of mammalian urothelium formed by the asymmetric unit membrane - this is believed to play a role in strengthening the urothelial apical surface to prevent the cells from rupturing during bladder distension.
Statistics
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PSSM-Id: 462150
Aligned: 2 rows
Threshold Bit Score: 299.628
Created: 22-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
P38575        20 LAPGTADFNISSLSGLLSPALTESLLIALPPCHLTGGNATLMVRRANDSKVVKSDFVVPPCRGRRELVSVVDSGSGYTVT 99  house mouse
XP_001380648  33 PHLGSAEFNISSLSGLLSPALAESLLVALPPCHLTGGKASLTVRRVNESAGMTHNFTVPPCRARRDLVSVVYNSGSFSIT 112 gray short-tail...
P38575       100 RLSAYQVTNLTPGTKYYISYRVQKGTSTESSPETPMSTLPRKNMESIGLGMARTGGMVVITVLLSVAMFLLVVGLIVALH 179 house mouse
XP_001380648 113 RLSAYQVTNLIPGTKYFVYYSVEKGTAVESSNKVQMATLPRRKVETLGLGMARTGGMIVITVLLSVAMFLLVVGLIVALA 192 gray short-tail...
P38575       180 WDARK 184 house mouse
XP_001380648 193 LGVHK 197 gray short-tailed opossum
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