4L3I_B        20 QKALNHLREIWELIgIPE----DQRLQRTEVVKKHIKELLDXX------IAEEESLKERL----IKSISVCQKELNTLC- 84  human
Q9HDY1        38 EKHFSKIERLHQVLgTDG-------------DNSSLFELFTTAmn--aqLHEMEQCQKKLeddcQQRIDSIRFLVSSLKl 102 Schizosaccharom...
XP_003956744 107 EKLLGDLHVFYQKIgYSNldiqKKEEAIFSTLSESINNFYQDAqtemenLSTSNDMEQEIlnkiLENLNDPNGIRTIPDl 186
P50275       102 EKLLENLNVIYQNIgYSNteiiTKEKIIFTTISNSIKQFFEQAdeelkrLSAENGIEQDIlnniLERINDPSGIKTIPDl 181 Saccharomyces c...
EJT42211     102 ERLLENLNVIYQNIgYSNseiiNKEKLIFTTISDSIKQFFEQAdeelkrLSVENGIDQDIlnniLERINDPSGIKTIPDl 181
Q9LZY0        17 GLLLRQLQEIWNEMgETE----DEKDASLADIEKECLSVYKRK------VEEASRGKANL----LKEIAVGRAEIAAIGs 82  thale cress
KRH40591      18 HLLLKELQIIWDEVgESD----SRRDAMLREIEHKCLDLYRKE------VDEAKLCRAQI----QQEIADNVAEIAGICa 83 
XP_006606398  17 GTLLYELQIIWDEVgESE----SDRDRMLFELEQECLEVYRRK------VDLANRSRAQL----RQAIADCEAELAAICs 82 
Q9VZ61        15 AEHFDELHAMWSRM-FEP----QACEDCLARLKDHVHTFYTDL------RKETSDKEQGI----LNDIAVLRNEASGLR- 78  fruit fly
XP_001963496  15 SQHVDRLHELWSHM-FEP----KTCEEFLVRLKDHADSFYTDL------LNESREKQQCI----QKEISSLRAEASTLT- 78 

4L3I_B        85 ----SELHVE----PFQEEgETTILQLEKDLRTQVELXRKQKKERKQELKLLQEQDQELCEILCX------PHYDIDSAS 150 human
Q9HDY1       103 tddtSSLKIE-----------SPLIQCLNRLSMVEGQYMAQYDQKLSTIKEMYHKLESYCNRLGS------------PFV 159 Schizosaccharom...
XP_003956744 187 yirnSILFETrktvPQSPKkPLSLLNKKSLLESAKIFIFNAYIPKLISFLNNALNLQIIINSVGTies-maEEDVQFINN 265
P50275       182 yirnAILLQEsktvPQSPKkPLSLLSKKAALDTAKKFVLGSFLPRLRDYLKSLITLKHLIQSVKEnlpgltEADNEAIAE 261 Saccharomyces c...
EJT42211     182 yirnAILLQEsktvPQSPKkPLSLLSKKAALDTAKNFVLGNFLPQLHSYLKSLITLKQLIECVKEdlpgltEGDSKTITA 261
Q9LZY0        83 smggQEIH-------SNSRlGENLKEELENVNVQLDGLRKRKAERMIRFNEVIDQLLKLSLQLGNpt--dyLKKFAAEET 153 thale cress
KRH40591      84 amgeQPLH-------FDPKsCGSLKKARETVVSQLEEMRKLKTKRKKQFSEVLYHLKNISSELYGs----mVANAYLEEN 152
XP_006606398  83 smgeRPVHIR-----QTDQnAGSLKEEHARILPQLEEMQKRKIERRNQFIEIQEQIQSISIEIYGpr--eyIP-AVEDET 154
Q9VZ61        79 ----RLLHKAv--dIGERPdDVPMEIWYIKLEKYIEQLRKELVSRRAEIRELLHQQQQLCDELGE------QPLSLLADP 146 fruit fly
XP_001963496  79 ----HLLHEPm--dIGDRPeDMPLVLWQLKLDESIEHLRDGLAKRRAEISDMLQKQEHLCKELGE------QPLPLLDDP 146

4L3I_B       151 VPSLEE----------LNQFRQHVTTLRE------------------------------------------TKASRREEF 178 human
Q9HDY1       160 LPDFENsflsdvsdafTESLRGRINEAEK------------------------------------------EIDARLEVI 197 Schizosaccharom...
XP_003956744 266 IPKLYV----------IQACLKSLNETNEisqisnfigsnkklflysdqf-khltpkrnerlaeltkyygtEYDFRFCEV 334
P50275       262 FPELST----------LTAYLLQIENGKGdiglsmkfiidnrkdilkgsafktineesvkhmnevikiyeeEYERRFKSV 331 Saccharomyces c...
EJT42211     262 FPELAI----------LTTYLVQIGNTKDninlsmkfikdnrddilkgsafktinedsvihmneiikiykeEYERRLESI 331
Q9LZY0       154 DLSLQR----------LEELRSQLGELQN------------------------------------------EKSKRLEEV 181 thale cress
KRH40591     153 NLSLKR----------LEELQKQLLQLQN------------------------------------------EKASRLKQV 180
XP_006606398 155 DLSLRK----------LEELHRQLHALQI------------------------------------------EKSSRLKQV 182
Q9VZ61       147 LPLPEE----------MDPFREHLAQLRD------------------------------------------QRVQRLRDM 174 fruit fly
XP_001963496 147 LPTVEE----------MGYFREHLDQLRD------------------------------------------QRVRLVEEM 174

4L3I_B       179 VSIKRQIILCXEELDHTPDTSFERDV------VceDEDAFC-------LSLENIATLQKLLRQLEXQKSQNEAVCEGLRT 245 human
Q9HDY1       198 NSFEEEILGLWSELGVEPADVPQYEQ------LleSHTNRPnd---vyVTQELIDQLCKQKEVFSAEKEKRSDHLKSIQS 268 Schizosaccharom...
XP_003956744 335 KKLIKNIETLLHELRLNATDNLNKDEielltkYsrIEKASEney--vpLNDDLLNKFKFIKKQYEIVKSQRFEEKKLLLD 412
P50275       332 LTKKVSISSICEQLGTPLATLIGEDFeqdlrsYgeEENSTSeipnfhpVDRERMSKIDITLEKLQAIHKERADKKRLLME 411 Saccharomyces c...
EJT42211     332 LIKKNTIFSISEELEIPLSTVVNENFerdlrsYgeEKSLISdlptfhpVDREIMCKIDIAAEKMESIHCERTHQKNLLME 411
Q9LZY0       182 ECLLKT----LNSLCSVLGEDFKGMIrgihssLvdSNTRD--------VSRSTLDKLDMMIVNLREAKLQRMQKVQDLAV 249 thale cress
KRH40591     181 SDQLNA----LNSLCLVLGLDVKDKIceicptMvnSTVTKD-------VSDNTIKNLTSEIQSLREVKIHRMQKLQSFAA 249
XP_006606398 183 QEHLCT----LNSLCLVLGFDFKQTIngihpsLvdSKGSKS-------VSNDTIQQLAVAIQELREVKLQRMQKLQDLAT 251
Q9VZ61       175 DELRQNIKRNIKLLELQLRTDSEKRL------L--NADNHK-------LTPYAYVRLQEMDKEFADQVQDLIDRIDEMRG 239 fruit fly
XP_001963496 175 KELRQSIKQDMKVLGCLPQSDAEERL------L--NQVNHT-------LTPDTFKSLRRMQAEFAEQVKELHEQIDDMRQ 239

4L3I_B       246 QIRELWDRLQIPEEERe-------------AVATIXSGSKAKVRKALQLEVDRLEELKXQNXKKVIEAIRVELVQYWDQC 312 human
Q9HDY1       269 EVSNLWNKLQVSPNEQ--------------SQFGDSSNINQENISLWETELEKLHQLKKEHLPIFLEDCRQQILQLWDSL 334 Schizosaccharom...
XP_003956744 413 NCRELWCKLKVPEEYTs-------------FFLNKNNNLSLDVIDNFKIEFQRLQTMKKELIKDLITESWEKINELWDTL 479
P50275       412 QCQKLWTRLKISQEYIk-------------TFMRNNSSLSTESLGRISKEVMRLEAMKKKLIKKLISDSWDKIQELWRTL 478 Saccharomyces c...
EJT42211     412 QCKKLWGRLRIPQEYVg-------------AFMQNNSSLSTETLDRISKEVTRLETMKKKLIKKLISDSWDKIRELWDTL 478
Q9LZY0       250 SLLELWNLLDTPAEEQkifhnvtcsialteSEITEANILSVASIKRVEDEVIRLSKIKITKIKEVILRKRLELEEISRKM 329 thale cress
KRH40591     250 ALLEMWDLMDTPMEEQqkfhhvtskitaleSEFTESKILSIDSVIYLEKEVERLQVLKSTKMKELLRKKKLELEEICRKT 329
XP_006606398 252 TMLELWNLMDTPIEEQqmfqnvtcniaaseHEVTEPNTLSVDFINLVEVEVARLEALKSSKMKELVLKKRTELEEICRKT 331
Q9VZ61       240 KIECLWQRLRMTDEYAm-------------RRVREATSYNQCTYDILREELERCQAMRQQNLIAFIEQLRIEINEWWDLS 306 fruit fly
XP_001963496 240 KIHVLWERLQDTDEYAq-------------RRVRESTAYTQHTYDVLREELHRCQALRRQNLKVFIDRLRVEIKAMWELT 306

4L3I_B       313 FYSQEQRQAFAPFCAEDY--T------ESLL--QLHDAEIVRLKNYYEVHKELFEGVQKW-----EETWRLFLEFERKAS 377 human
Q9HDY1       335 FYSEEQRKSFTPMYEDII--T------EQVL--TAHENYIKQLEAEVSANKSFLSLINRY-----ASLIEGKKELEASSN 399 Schizosaccharom...
XP_003956744 480 QIPNEDRANFIGKFKNMKetSqglqddENLL--EVCEVEIKNLNEQLKIYEPVLNLIKEF-----QSLQKDKIFLENSSK 552
P50275       479 QYSEESRSKFIIVFEELRnsAttlqedELLL--ETCENELKRLEEKLTLYKPILKLISDF-----ESLQEDQEFLERSSK 551 Saccharomyces c...
EJT42211     479 QYPEASRSSFIIIFEELRgdAttlqedELLL--ETCESELKRLEDKLVLYKPILKLMSDF-----ESLQKDQEFLERSSK 551
Q9LZY0       330 HMATEVLKS-ENFSVEAI--EsgvkdpEQLL--EQIDSEIAKVKEEASSRKEILEKVEKWmsaceEESW-----LEEYNR 399 thale cress
KRH40591     330 HLTTQT--------------VfqsqhsLELLdyDQIEHLITKTKEEALNRKEILEKVEKWlvacqEESW-----LEEYNR 390
XP_006606398 332 HLIPEIDNA-VESAVEAI--EsgsvdpAFVL--EQIELQISQVKEEALGRKEILEKVEKWlaacdEESW-----LEEYNR 401
Q9VZ61       307 LKSTEERRRFTTYYCDTQ--T------EDVL--EQFEKELDNLKEFYNSNRKIFELYANR-----GELWTRMEALEAKAN 371 fruit fly
XP_001963496 307 LKGPAECKRFASFYNTHL--T------EEDL--ELHELELDKLKRLYEGNKKIYEMYSNR-----GEMWARMIALEAKAN 371

4L3I_B       378 DPNRFT-NRGGN---L-LKEEKQRAKLQKXLPKLEEELKARIELWEQEHSKAFXVNGQKFXEYVAEQWEXHRLEKERA-- 450 human
Q9HDY1       400 DASRLT-QRGRRdpgLlLREEKIRKRLSRELPKVQSLLIPEITAWEERNGRTFLFYDEPLLKICQEATQPKSLYRSASaa 478 Schizosaccharom...
XP_003956744 553 DSSRLLaRNSHK---IlLKEENTRRRLKRHFPKVIKELKVKLVEAEDFFHKPFSFNGEKLQDIILKEEEEFMSRYPKSvl 629
P50275       552 DSSRLLsRNSHK---IlLTEEKMRKRITRHFPRVINDLRIKLEEADGLFDQPFLFKGKPLSEAIDIQQQEIEAKYPRCrv 628 Saccharomyces c...
EJT42211     552 DSSRLLsRNSHK---IlLTEEKMRKRITRHFPRIINDLRIKLEEADRLFDQPFMYKDKLLTEAIDIQQQEIEAKYPRCrv 628
Q9LZY0       400 DDNRYNaGRGAH---LtLKRAEKARLLVNKLPGMVEALTAKVTAWENERGNEFLYDGVRVLS-MLGQYKTVWEEKEHEkq 475 thale cress
KRH40591     391 DDNRYNaGRGAH---LtLKRAEKARALLSKIPGIVETIILKVKAWEKERGQEFMYDGSRLLS-ILEDYSTLRQEKENErq 466
XP_006606398 402 DDNRYNaGRGAH---LtLKRAEKARALVNKIPAMVDGLTSKTISWEKEKGIEFTYDGIRLLS-MVEEYNILRQEKEQErr 477
Q9VZ61       372 DPNRFN-NRGGQ---L-LKEEKERKTIMSRLPKIDQQITELVQVYMSETHTPFLVHGVDILERMSADWERHRQSKKQP-- 444 fruit fly
XP_001963496 372 DPNRFN-NRGGQ---L-LKEQKERKAITAKLPKIEQQIAELVEEYVSQAKVPFLVNGVNILEQMAADWENLRQPKQAPpl 446

4L3I_B       451 KQE--RQLknkk----------------------qtetEXLYGSAP-------RTPSKRRGL 481 human
Q9HDY1       479 ANR--PKTatttdsvnrtpsqrgrvavpstpsvrsasrAMTSPRTPlprvkntQNPSRSISA 538 Schizosaccharomyces pombe 972h-
XP_003956744 630 NFGrtRPVvnstrvndnhsr------khatipktttmrSKTYSTAElmsrtvhKTPIRHKSD 685
P50275       629 RMQrsKKGkcgankenkvi--------kntfkatessiRVPIGLNLndanityKTPSKKTIQ 682 Saccharomyces cerevisiae S288C
EJT42211     629 RMQrsKKGksamdknnkit--------katskltqksiRIPVDLDLntikithKTPSKTTMN 682
Q9LZY0       476 RQRdmKKLhgql----------------------iteqEALYGSKP--------SPNKSGKK 507 thale cress
KRH40591     467 LQRdqKKLqgql----------------------maehETLFGSKP--------SPAFKSGY 498
XP_006606398 478 RQRdlKKLqgqm----------------------iaeqEALYGSKP--------SPSKPQSV 509
Q9VZ61       445 SAQ--KKDgsn------------------------tsgQMKPPMVP-------LTPNTQKSN 473 fruit fly
XP_001963496 447 SGKkev------------------------------ghKMMPPSAP-------LTPKALKGK 471