Conserved Protein Domain Family
PIF

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pfam05092: PIF 
Per os infectivity
This is a family of dsDNA Baculovirus proteins. It is required for the infectivity of the OBs or occlusion bodies. It is a structural protein of the ODV envelope required only in the first steps of per os larva infection, as viruses being produced in cells expressing the gene for this protein but not containing it in their genomes are able to produce successful infections. Baculoviruses are large DNA viruses that infect arthropods, mainly members of the order Lepidoptera. In their life cycle, they produce two kinds of particles, a budded, non-occluded virus (BV), which buds out of the infected cell and is responsible for the cell-to-cell transmission of the virus, and an occluded form, the occlusion body (OB), which is responsible for protecting the virus between encounters with larvae. A variable number of virions are included in the para-crystalline structure of the OB, mainly constituted by the virus-encoded polyhedrin protein; these virions are called occlusion body-derived virions or ODVs.
Statistics
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PSSM-Id: 282889
Aligned: 4 rows
Threshold Bit Score: 697.787
Created: 22-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
Q6JP91   7 ILIFVCIFFIYSFI--------NNFTNYRIndt---nkdEIVLYKNLDTDVLKlPSDEIVLETNPKTCHTELTPCTTBGD 75  Neodiprion lecontei n...
Q8B9E2   8 LFLLVIIAIVYTYVdl----idVHHEEVRY---------PITVFDNARAPLIE-PPSEIVIEGNSHECHKTLTPCFTHGD 73  Rachiplusia ou MNPV
Q91EY0   8 VTLLVLLTIL------------AHWSNVRLyttthnlhtDTPIYDNTHVPLLD-PPKEIIINENNVSCHKTPTPCISNAD 74  Cydia pomonella granu...
Q919P0   5 VLLVMVIFILFILTqilitrniAHAQRQLVddp---pdrNVQTFPYDPDLTIQlPEKPIELEGNPVQCHKTPTRCTGQGD 81  Culex nigripalpus nuc...
Q6JP91  76 CFECQELLAKC-QSFDEEVQIEI-----GSTTFVIPPNESYCLAIDAKKSRSCNVYTGKWILVETDT-GLGLICSCLYPG 148 Neodiprion lecontei n...
Q8B9E2  74 CDLCREGLANC-QLFDEDTIVKMrgddgQENETLIRAGEAYCLALDRERARSCNPNTGVWLLAETET-GFALLCNCLRPG 151 Rachiplusia ou MNPV
Q91EY0  75 CQLCLEGLASC-QLFNDTVILEId----DNQQMIVEPGQKLCLAIDNRSARSCNPNTGTWMLRQVDNiNMALICHCDTPG 149 Cydia pomonella granu...
Q919P0  82 CLQCRELRARCvEILEDITLVQP-----DGTEVVLEAGNNYCLATSQEHARSCTPLTGKWILIQMND-MWSAVCSCTSPD 155 Culex nigripalpus nuc...
Q6JP91 149 LVTQTDIYSDCDVSVGCNNAGVISNLHTSPLTCDCNDGYVADTAND--QPICRPRQIKDVIYDTTLFPREPCPDNYISVA 226 Neodiprion lecontei n...
Q8B9E2 152 LVTQLNMYEDCNVPVGCAPHGRIDNINSASIRCVCDDGYVSDYNADteTPYCRPRTVRDVMYDESFFPRAPCADGQVRVD 231 Rachiplusia ou MNPV
Q91EY0 150 LVTQLNIYDDCSFPVGCKPHGIIADINSSPLTCLCENGFVPEL-SDtnTPYCRPQVMRDVMLDPNFFHRPPCRDGFLPAE 228 Cydia pomonella granu...
Q919P0 156 MFIKMNLWGDCDVPVGCAPNGVVVIVNVIEMKCNCNVGFVSDVDANg-RPYCRPITLRDASIDGQVFKRPPCSDGFIPVS 234 Culex nigripalpus nuc...
Q6JP91 227 HDGLDESYRQQFiLSNICIPDPCSIDPITTQ----------------TISG----------YGqikhryIDEnivyfCNC 280 Neodiprion lecontei n...
Q8B9E2 232 HPALNDFYRRHFrFEDICVIDPCSVDPISGQrtsgr------lfhqpIVNG----------VG------ING-----CNC 284 Rachiplusia ou MNPV
Q91EY0 229 HPAFDQVYRRQI-GANVCLPDPCSVDPLTGVrheg--------rvvyEVEG-----------G------ADGgelvmCRC 282 Cydia pomonella granu...
Q919P0 235 HPALHTDYGRNL-FGDICVRDPCSVDPITNQpinarleysalptmpdTVAGrcvgtavsqtYG------IFGgggsmIKL 307 Culex nigripalpus nuc...
Q6JP91 281 SAQTGAFGI----NIGNSMLKTNSYNLSNACIQPLLKQYEFGDDtWMKWFWGRSDPLNVCDVDFXFRLAKTYF-KDAYHQ 355 Neodiprion lecontei n...
Q8B9E2 285 PVDDGLLPVfnrhTADTGMVRQSDRTVANACLQPFNVHMLSLRHvDYKFFWGRSDHTEFADADMVFQANVNQLsHERYRA 364 Rachiplusia ou MNPV
Q91EY0 283 NINDNLYPVysvaSMLNTVYTEFDREIANACVKPLIVGRRDVRS-DLKVFWGRDS--LKSDADIVFQVDEHHV-YEPYRV 358 Cydia pomonella granu...
Q919P0 308 PPED--VPVk---LADHAISIARPRSLGN----------------NMLYFWGRRNTVMEADMDLLQTTIFREV-NERYLN 365 Culex nigripalpus nuc...
Q6JP91 356 ILQN---------VVGDIGTLKFAIQETYyy--tSTNEINHFT-----RAIKLME-RTWQPICYKHFIRAC--------- 409 Neodiprion lecontei n...
Q8B9E2 365 ILYPlleshpdvtEITTVGTGVMKISVSY-----DTTLKNILLpssvfRLFRFKEnGTTQPVCFFPGVGRCit------- 432 Rachiplusia ou MNPV
Q91EY0 359 LLYRrith-hptlDLTTSFILKFQLHTAYtvsamDSNQRDVFQ-----GYWQLNHaRTSNNTCPLPGIGECrnpqtcgni 432 Cydia pomonella granu...
Q919P0 366 Ian--------wsTVDNVVVFRFRVTEGH-----EQRHRNLFT-----ELLKHMN-ELDQPRCMQHQRPGC--------- 417 Culex nigripalpus nuc...
Q6JP91 410 --TEDVCVwRTPRTFLVGSKEFFTGQKCQLSRLEdpivlpdpnyifedsvvYPIIAYGPPKHYGIA-FPVV-----FYIY 481 Neodiprion lecontei n...
Q8B9E2 433 -vNSDSCI-RRHAGAQVWTAETFTNSWCVLSREG-----------------THIKIWSRASRYPRGdAPAAlrlrgFFLN 493 Rachiplusia ou MNPV
Q91EY0 433 tcTYNPCI----------------GNSVVLGYYSrcfffkanrrfdnvgtiAQVCVWNAPTYYNSDnVPVT-----FYLN 491 Cydia pomonella granu...
Q919P0 418 --TLDVCVwNDPRPGLVNMHNFFTGQRCYLSRTSqrfv---------gmsaGLLCAFGLPSYYRDGeAPAV-----FVL- 480 Culex nigripalpus nuc...
Q6JP91 482 ------------NDITFLgydprsssfydqTVYHINSEMIT--EDIDTLSSLIYTFPNYS 527 Neodiprion lecontei nucleopolyhedrovirus
Q8B9E2 494 ------------NDRERN------------TIRAVTTGDMTqgQQIDALTQILETYPNYS 529 Rachiplusia ou MNPV
Q91EY0 492 algatdggygisNDVR--------------TLYFTNSGATVpqSQFNTLIQLLATYPYYN 537 Cydia pomonella granulovirus
Q919P0 481 ------------DDVYRNggsf-----pgiRVQHQTSAFVS--NQTGAVNSYLGSFPFYS 521 Culex nigripalpus nucleopolyhedrovirus
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