Conserved Protein Domain Family
PD-C2-AF1
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pfam09310: PD-C2-AF1 
POU domain, class 2, associating factor 1
Members of this family are transcriptional coactivators that specifically associate with either OCT1 or OCT2, through recognition of their POU domains. They are essential for the response of B-cells to antigens and required for the formation of germinal centers.
Links
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Statistics
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PSSM-Id: 430516
Aligned: 4 rows
Threshold Bit Score: 368.124
Created: 21-Apr-2021
Updated: 29-Sep-2021
Structure
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Aligned Rows:
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Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
XP_008119288   7 SAPEPPPpqpSPRPYQGVRVKEPVKELLKRKRGSLqnANGATAAATTVFFPHQSLPSYSPAGQVCADSEFVASPL--VDD 84  green anole
Q90ZH6         7 SASEQQP---QPRPYQGVRVKEPVKELLKRKRGNV--HNATAAAATTVVLPHQPLPSYSPMGQPCIDVDAAAPALpgAEE 81  chicken
XP_001381387  31 SAPEQTPv--PPRPYQGVRVKEPVKELLRRKRGLA--SSGLTVAATTVVLPHQPLATYATMGPSCLDMEVPTSTV--TEE 104 gray short-tail...
XP_546531      7 TAPEQAPa--PPRPYQGVRVKEPVKELLRRKRGHA--SSGAAVTPTAVVLPHQPLATYTTVGPSCLDMEVSASTV--TEE 80  dog

XP_008119288  85 GTLYSGWLAQPSPATLQPLTQWAAYPDYVPHEAVSCPYTGEMYVQPVCPSYTLVGTSSVLTYASQPLITNLAARStSAPA 164 green anole
Q90ZH6        82 GALCSSWLSQPSPSSLQPLTQWTTYPDYVSHEAASCPYTADMYIQPMCPSYTLVGPSSVLTYASQPLITNFTPRS-STPA 160 chicken
XP_001381387 105 GALCTGWLSQPAPATLQPLTPWTPYPEYMPHEGVSCPYSTDMYVQPVCPSYTVVGPSSVLTYASQPLITNFTTRN-ATPT 183 gray short-tail...
XP_546531     81 GALCAGWLSQPGPATLQPLAPWTPYTEYVSHEAVSCPYSADMYVQPMCPSYTVVGPSSVLTYASQPLITNVTTRSaAAPA 160 dog

XP_008119288 165 VMPHLDMMEQQGPLSYFPWTQPISTLPAPSLQYQAASSALPAPQFLPLPVSVPETVSQDLEDTRKDLGGLSMEKLLLQEE 244 green anole
Q90ZH6       161 VVPQLEVTEQQPPLTYFPWAQPLSALPAPTLQYQPASSTLPTPQFVPLPISIPEPAPQELEDARRVIGTLPIEKLLLEDE 240 chicken
XP_001381387 184 SGPQLEGTEHQAPLTYFSWPQPISALPSSTLQYQSPAPSLPGPQFLPLPISIPEPVPQDLEDTRRAINTLPIEKLLLEEE 263 gray short-tail...
XP_546531    161 VGPQLEGPEHQAPLTYFPWPQPLSTLPTSTLQYQPPAPALPGPQFVQLPISIPEPVLQDMEDPRRAISSLTIDKLLLEEE 240 dog

XP_008119288 245 NHGIFDLSNSLPVEG 259 green anole
Q90ZH6       241 DNDTYVLNHALSVEG 255 chicken
XP_001381387 264 ESDTYGMNHTLSVEG 278 gray short-tailed opossum
XP_546531    241 DGDAYALNHTLSVEG 255 dog
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