Conserved Protein Domain Family
WRW

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pfam10206: WRW 
Mitochondrial F1F0-ATP synthase, subunit f
This is a family of small proteins of approximately 110 amino acids, which are highly conserved from nematodes to humans. Some members of the family have been annotated in Swiss-Prot as being the f subunit of mitochondrial F1F0-ATP synthase but this could not be confirmed. The sequence has a well-conserved WRW motif. The exact function of the protein is not known.
Statistics
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PSSM-Id: 431134
Aligned: 20 rows
Threshold Bit Score: 137.037
Created: 23-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
XP_003098322  45 EIGLFDKRWNKNVHGPYCHWRYYGKLDTKLMDVKLGELPAWIARRDKTPSAFYNEFMRNVWRVHNLYYSGPvyNNTVKVI 124
Q4PM56         2 AIGDYPAEYNPKVHGPYDPARYYGKPDTPFSELKLTEIGSWLARRKKSPQSVAGLFSRVYWRWQQKYVLPR--RAGIVGA 79  black-legged tick
Q201W3         2 GIGDYPAEYNPKVHGPYDPARYYGTPDKPFGQLKLGEVTEWVGRRNKSPKAIAGLFSRAYWRWSHKYVQPK--RTTVAPL 79  pea aphid
XP_003240133  29 GIGDYPAEYNPKVHGPYDPARFYGTPSTPFSELKLCEVPQWLKCRNKSAKSLAALFSRAYWRWSHQYVQPK--RTTAAPL 106
EEB11001      10 sWGEYPPEFNKAVHGYYDPSRYYGKPDTPFTEVKLKDLSSWFSRRQKTPRACLNALNRAYWRFNWHWLLPK--KPGYAGF 87 
XP_018645245   3 NFGLLPKEYNARVHGVYFPGTYYGKKDIPFGDVQLGQLSEWFSRRSKNPVDMLRAVSRFYWRYAFRWVMTK--RPSVVPF 80 
ESO00582       1 -IGEYPPEYNPRVHGPYYPSRYYGKADTKFTQVKLGEMGQWLGRRNYDPLSMLRCIGRGWTRWQMKWMMPK--RASIAPV 77 
XP_393421     16 twGCYPEGYNPAEHGPYDPSRYYGKPDTPFGEVKLGELPAWFSRREKGFRAFAALISRAHWRWQLKYIHPR--KANMAPL 93 
XP_015787248  15 tFNCYPPEYNRAIHGPYDPRINYACKDKGILDVKLNELPSWLMRRRFTPSAIAGVMSRHFYRSCHHHFIAV--RSRSNMF 92 
EFA09167       2 GFGDYPAEYDPKVHGPYDPARFYGKADTPLAQVKLGELGGWLARRNKHPQAIAGAISRAYWRWQHKYVQPK--RSGIAPF 79 
XP_003098322 125 FRFIFAYSFLNWLVKSHRYVDFQK 148
Q4PM56        80 AQFCVAWSALFYWINYNKLKHERR 103 black-legged tick
Q201W3        80 IHILAGSMLFFYAINYGKFVHHRN 103 pea aphid
XP_003240133 107 IQGLTGMMLIFYIINYGKTIRHRN 130
EEB11001      88 LQMYFGFFLVNYLFSYKALQKHQR 111
XP_018645245  81 FQLTFSFAAFRYFSDYAEHRSHKH 104
ESO00582      78 VQFCMGVSLFFYVNNYRr------ 95 
XP_393421     94 YQAAFLASAFGYCINYLRLRGHRN 117
XP_015787248  93 FTVLLITAAMGYVFQLHNMSHHRR 116
EFA09167      80 LQVVTASMVFFYVINSQKLSRHKN 103
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