Conserved Protein Domain Family
NUC173

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pfam08161: NUC173 
NUC173 domain
This is the central domain of of novel family of hypothetical nucleolar proteins.
Statistics
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PSSM-Id: 462386
Aligned: 123 rows
Threshold Bit Score: 141.122
Created: 23-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
XP_001732587  469 LREALGkH--ALRYTHTRSDILHILASMLSRLRYPLevggPPPaeplLMQAVVDVAALRAHRHFDARPDADAVLGSAISA 546 
OWR55062      490 VFKTIS-SglDNPFNQAIKHVILTIAVCFEIGNEKVet--------iLEQLLKKLNDRRESHNFHNEKEAEYATGCAVKS 560 
XP_008198233  479 CFSCVE-AglGYQYHSVWHQVLHLIAVMFEVGGQNC----SHM----LLNCLKSLSELRDSYKFSYNNELEHAVGAAIRS 549 
EGI69855      477 VVEIMH-KtlSYQYIGAWRHVLHLIAVLFQVTGKLKlq--------eLDNVVKTLGNLRDSHDFAHNRDAEYAIGAAIRA 547 
XP_019697747  462 IISQMH-KtlSYQYLEAWYHVLHLIALLFQITGRSKlq--------gLLNIMQSLGELRDSYNFTHNSDVEYAIGAAIRM 532 
XP_011259421  479 IVSIMH-KtlSYQYLEAWRHIFHLIALMFQVIGKSKlq--------eLTDIIRSLGELRDSYNFAYNSDVEYAIGAAIRA 549 
XP_001947790  463 LFNLVT-QclSYQYKNACSQVLHTLSTFFKFYGKCAps--------iFLECIKSLGQLRDSNEITFVNELEMTIGAGIKY 533 
8_pfamImport    2 IACILE-DllTHKVGTALPHILHLLSAFFKECGEHCae--------lLTPCLKSVAELRDNTEFTYKSELENTVGSAIRT 72  
XP_002432387  458 VFTVVE-NclKYQFNNAWVQVFTLLGVLYEVIGKDGee--------yIGNSLRTLGNLRESFNFLYVSELDYTIGKAIRS 528 
XP_004933719  495 VFKVIG-AglDNPFNQAIRHVILTIAVCFEIANEKIss--------tLEPLLRKLNDRRESHNFHNDKEVEHATGCAIRS 565  domestic silk...
XP_001732587  547 CGPRVFL--SYLPLDLLDAktgrpNTqggVRGRAWLLPLLREHISNTELAHFVEELVPLSEALFEVRVQAEqpsdgSAPR 624 
OWR55062      561 LGPEFVL--RIIPLKDGds---------iNIDRSWLLPVLKEKVTNSNLKFFATEILELATFCRKKSRELS-----DKND 624 
XP_008198233  550 MGPETVI--NVISLKKDng--------dlNLDRSWMLPVLKENIKASTIEYFMKGILPLALYCQRRSAQLA-----EAND 614 
EGI69855      548 MGPRAVL--DILPLRID--------EntiNLKRSWMIPLLKDCITGGTISFFKDILLPLALRCEEKAK----------GS 607 
XP_019697747  533 MGPDVVL--KVLPLQVD--------SstiNLKRGWLIPLLKDCITCGSISFFTDVLLPIVQICEQKVK----------KE 592 
XP_011259421  550 MGPQVVL--NILPLRID--------DdtiNLKRGWLIPLLKDCITGGTISFFKDVLLPIALTCEEKS-----------KT 608 
XP_001947790  534 IGPEYIIsdKVIPLKVDdv---------gEFKRSWLLPVLKDSISNSTLKCYIDHFLPLALKCREMYENAL-----KAND 599 
8_pfamImport   73 MGPQIVI--DTVPFKIT--------PgdrQFKRSWLLPVFKDNIKNATLKCFVDRFLPLAAVCRNEGDRLK-----KVND 137 
XP_002432387  529 LGPEMVL--KYIPIVITGE-----EVn-fEFKTCWLLPILKDNIQASSLKFFSEYFLPMALICDKKSKELN-----ERNE 595 
XP_004933719  566 LGPEFVL--KTIPLRDN--------PdsiNLERSWLLPVLKEKITHSNLKYFATEILEMATFCRKKSRELS-----QAGD 630  domestic silk...
XP_001732587  625 PVEAKVMEALIEQIWVCFPGYCDLCRDVDTSLtPHVLELLINVLRTQTNLRPAVLKGLELLVQRN 689 
OWR55062      625 TTGSHTYDLLCNQFWSLLPSFCNYPKDIKDNF-KYLAKVLGNVLKENQEFRLSVMQALRKLITCT 688 
XP_008198233  615 GIGAHSSELLYMQLWNLLPCFCNHPTDIKDSF-KSVAKVLGTAISDRKELRLSVMASLRKLIASA 678 
EGI69855      608 LADRKIYECLVTQIWSILPSLCNDASDVKDNF-KSIAKLLGVAINDRRDLRPSAMTALRKLISKA 671 
XP_019697747  593 PINGKTYEFLVPQIWSILPSICSDASDVKDNF-KNIAQKLGKTINERKELRLPVLSALRKLIVKA 656 
XP_011259421  609 GIEGKTYEFLVPQIWSILPSICNNANDVKDNF-KSIAKLLGMMISDRKDLKLSIMAVLRKLIGKA 672 
XP_001947790  600 KITAISYDLLESQIWALLASFCSNPSDISTSF-RIIARTMGTMLSSRKELRDTILVSLRKLIASV 663 
8_pfamImport  138 QIGAVSYDLLQSQIWALLPSFSAHPTDISTSF-GSLAKTLGGLLNSRKDLRLIILSTLRKLITHS 201 
XP_002432387  596 KIGGHSYDLLQLQIWSLLPAFCNGSDDVKENF-KIIARIIGNVIEEKKHVRIHGMAGLRKLITRN 659 
XP_004933719  631 VPGSHTYELLCNQFWALLPSFCNSPKDIKDTF-KFMARVLGNVLKDNPEFRLSVMQALRKLIACS 694  domestic silkworm
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