Conserved Protein Domain Family
bHLH_AtMYC1_like

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cd18918: bHLH_AtMYC1_like 
basic Helix-Loop-Helix (bHLH) domain found in Arabidopsis thaliana MYC1 and similar proteins
MYC1, also termed AtbHLH12, or EN 58, acts as a transcription activator, when associated with MYB75/PAP1 or MYB90/PAP2.
Statistics
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PSSM-Id: 381488
Aligned: 10 rows
Threshold Bit Score: 90.8562
Created: 16-Apr-2018
Updated: 2-Oct-2020
Structure
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Aligned Rows:
 
putative DNAputative dimer
Feature 1:putative DNA binding site [nucleic acid binding site]
Evidence:
  • Comment:The N-terminal basic region of bHLH mediates high-affinity DNA-binding to specific hexanucleotide sequences
  • Comment:Based on the structure evidence that Arabidopsis thaliana MYC2 (5GNJ) binds DNA.

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
Feature 1        ##  ## ##   #                  ##                                       
Q8W2F1       338 LNQDDPSDRRKENEKFSVLRTMVPtv--nEVDKESILNNTIKYLQELEARVEELESCMGSVNFVERQRKTTE 407 thale cress
Q84TK1       248 TSPTERERRVHFNDRFFDLKNLIPnp--tKIDRASIVGEAIDYIKELLRTIEEFKMLVEKKRCGRFRSKKRA 317 thale cress
PNR52315     385 HFATERQRREYLNEKYQTLRSLVPnp--tKADRASIVADAIEYVKELKRTVQELQLLVQEKRRAAGDSSGGK 454 Physcomitrella patens
Q9LND0       217 IFPTERERRVHFKDRFGDLKNLIPnp--tKNDRASIVGEAIDYIKELLRTIDEFKLLVEKKRVKQRNREGDD 286 thale cress
F4IQQ9        24 TFLTERERRALFNDRFFDLKNLIPnp--tKGGEASIVQDGIVYINELQRLVSELKYLVEKKKCGARHNNIEV 93  thale cress
XP_022144464   8 DHAEAKRRREKLNHHFSSLRSLLPnasnsDNSEAAVLSDAVSYINELQVKMEDLESHLDVKKSNPEDEATSG 79  bitter melon
Q7X8R0       266 NFATERERREQLNVKFRTLRMLFPnp--tKNDRASIVGDAIEYIDELNRTVKELKILVEQKRHGNNRRKVLK 335 Japanese rice
Q5JNS0       178 VEKKEKQRRLRLTEKYNALMLLIPnr--tKEDRATVISDAIEYIQELGRTVEELTLLVEKKRRRREMQGDVV 247 Japanese rice
XP_024360345  60 EVVLERKLRSRMHGQLEQLRAVIPns--fTEEKASILADAYKYIEKLQRQVEELYYELGTESCFEEGSSCCE 129 Physcomitrella patens
Q8GX46       215 PFTTERERRCHLNERYEALKLLIPsp--sKGDRASILQDGIDYINELRRRVSELKYLVERKRCGGRHKNNEV 284 thale cress

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