Conserved Protein Domain Family
RPN2

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COG5116: RPN2 
26S proteasome regulatory complex component [Posttranslational modification, protein turnover, chaperones]
Statistics
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PSSM-Id: 227446
Aligned: 3 rows
Threshold Bit Score: 1201.69
Created: 7-Oct-2002
Updated: 23-Jan-2015
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
19113173  10 SIITSAGGLMALLDEQERELQVHALLKIYEFIDQLWPEISDDVTKIEVMYEDHSFPERELAALVVSKVYYYLGEYDEALL 89   fission yeast
19073969   1 --MQTIRILPNIRALLRDGRESEAIDVINAHVDVVAPHIKDDLRYIK------SSDPK--TSLCLSKIYFVLEDYQQAIE 70   Encephalitozoon cu...
730736     1 MSLTTAAPLLALLRENQDSVKTYALESINNVVDQLWSEISNELPDIEALYDDDTFSDREMAALIASKVYYNLGEYESAVK 80   baker's yeast
19113173  90 FALSSGPKFLHDKNSDYKETLIFKCIDMFIHKSAELYKNPK----ADPLDERLSGVVEGIFQKCYAKNEWRHVLGIAIEA 165  fission yeast
19073969  71 YALRAGD-LLVDDGSFYYTSIVY-------HMMDSADIGGD--------DRIRDFVLKVIGAEDVDDSLIGYLFSIKAYG 134  Encephalitozoon cu...
730736    81 YALAAKDRFDIDEKSQFVETIVSKSIEMYVQEASKQYTKDEqfytKDIIDPKLTSIFERMIEKCLKASELKLALGIALEG 160  baker's yeast
19113173 166 HRLDIIEYILNADKETD-------LKPYVLELAMTVVLDIEFRNRLLRLLLSSFLTETEPDYFSVGKCVVHLNDASVAAK 238  fission yeast
19073969 135 LLKEALVKYISDGNDCR----------RLLDLLISLGEEEGCLKEIYGMLAEIGPGK-KPFIFYVIDAYFYLEDVEKVKA 203  Encephalitozoon cu...
730736   161 YRLDIIESALKSKLDQDstsenvkIINYLLTLAITTVTNSKFRSSILRKSFDFLMNMPNCDYLTLNKVVVNLNDAGLALQ 240  baker's yeast
19113173 239 LLMKLSSQNDDKslLTAyQLAFDLEDSAPQEFLnsvmDLLPSPSVANSEEDAnadskkedsspcgyIIRILSGEQTVKYD 318  fission yeast
19073969 204 LIERLVKEDILL--CYD--VAFYTEDNYSPEIE-----------VA---DQR--------------VMSILSGEFKKKIL 251  Encephalitozoon cu...
730736   241 LFKKLKEENDEG--LSA-QIAFDLVSSASQQLL----EILVTELTAQGYDPA--------------LLNILSGLPTCDYY 299  baker's yeast
19113173 319 REFLYAHNNTDMLILNRTKDSLEARNSVFHNAVTFANAFMNFGTSSDSFFRDNLSWLSKANNWSKFTATAALGVIHRGYY 398  fission yeast
19073969 252 GAFLLEKNLTSFKFLES----IAR--TRTHYLG-LANSLMNLGTSNDTLYRNNADIFGQSSEWAKFSEVASIGMIHLFNS 324  Encephalitozoon cu...
730736   300 NTFLLNNKNIDIGLLNKSKSSLDGKFSLFHTAVSVANGFMHAGTTDNSFIKANLPWLGKAQNWAKFTATASLGVIHKGNL 379  baker's yeast
19113173 399 NQAMNILRPYLPEEDApsSSTYSEGGAFYAMGLIHAN-HGRGVTEYLR----EQLKHTEDE---IVQYGLLLGIGLTGMA 470  fission yeast
19073969 325 NP-YEILKNYLPSEVS-----QKEGGALMALGLIKAGtFSEEDTEYLL-----YFLDTEDTltpELAYGVCLGLGLINMG 393  Encephalitozoon cu...
730736   380 LEGKKVMAPYLPGSRA--SSRFIKGGSLYGLGLIYAG-FGRDTTDYLKniivENSGTSGDEdvdVLLHGASLGIGLAAMG 456  baker's yeast
19113173 471 SRDETLYESVKTILFNDNAVAGSAAGISMGLIMLGTASSAAIDEMLQYAHETQHEKIIRGLGIGIALIVYGRQQEADG-- 548  fission yeast
19073969 394 SANREILNKLKELSKVDRTLLVEASVYGMGMLGLNSWSVELLEDLRTIAGETEFERVKRAVGISFSLVLMFSEEMFYDec 473  Encephalitozoon cu...
730736   457 SANIEVYEALKEVLYNDSATSGEAAALGMGLCMLGTGKPEAIHDMFTYSQETQHGNITRGLAVGLALINYGRQELADD-- 534  baker's yeast
19113173 549 ---------IIKELNNDLDPTLRYAGMFATALAYCGTSNSKIVRDVLHISVSDVNDDVRRAAVCALGFICFKDPNALIST 619  fission yeast
19073969 474 nasngdfknYINELLYDKDSIMRANGVLSLGSAFVGTGRLGVISTLLPY-INDGDDDVKRAAVIAIGLVCCDDRDLLVGT 552  Encephalitozoon cu...
730736   535 ---------LITKMLASDESLLRYGGAFTIALAYAGTGNNSAVKRLLHVAVSDSNDDVRRAAVIALGFVLLRDYTTVPRI 605  baker's yeast
19113173 620 VELLVDSYNPHVRYGSAIALGIACANSGSNAALDLLSRLVEDATDFVRQGAMIAQAMILTQHNDQLNSKVSGIRKHFEQV 699  fission yeast
19073969 553 LEPLSENHNFFVRAAVAVVLGLFLSGTGDKVCTNILEALMYDTNSLVRQSACIGVGFITMQCNPELVPNYKRIIEKLNRL 632  Encephalitozoon cu...
730736   606 VQLLSKSHNAHVRCGTAFALGIACAGKGLQSAIDVLDPLTKDPVDFVRQAAMIALSMILIQQTEKLNPQVADINKNFLSV 685  baker's yeast
19113173 700 INEKHEDALAKLGATLAQGIIDAGGRNVTIALQTA-TGSLKLSAIVGLTVFLQYWYWFPLTHFMSLSFSPTALIGLDKN- 777  fission yeast
19073969 633 IVDKKESGAVELGAVLGRGLSEGGGRNIVFSVRNM-SGITSADRIAGAVLFLHYWYWHPLISMVSLCALP-T-------- 702  Encephalitozoon cu...
730736   686 ITNKHQEGLAKFGACVAQGIMNAGGRNVTIQLENAdTGTLDTKSVVGLVMFSQFWYWFPLAHFLSLSFTPTTVIGIRGSd 765  baker's yeast
19113173 778 LNAPKFSFISNVRPKLFAYPPKSVQPTAKTVQKVETAVLSTTVKAQARAKRAEREkasKGSNDDEMKIDKKTTE-EKEAT 856  fission yeast
19073969 703 ---TVFCFNEDLEEEEIEIP--------TSSRYNNLLICLPDIKKARRFKQKPKE-------DKEIVIESPSVLtFGSRC 764  Encephalitozoon cu...
730736   766 QAIPKFQMNCYAKEDAFSYPRMYEEASGKEVEKVATAVLSTTARAKARAKKTKKE---KGPNEEEKKKEHEEKEkERETN 842  baker's yeast
19113173 857 PMEMDEEKSQDISINGNSKKEEPksETLENFTRVVPAQLPYISFNLNGRYYPVRKFTG--GVLMLIDRESDKAPDLIELN 934  fission yeast
19073969 765 TIKQREECGIDAPAILFVKKKK---------------------------------------------------------- 786  Encephalitozoon cu...
730736   843 KKGIKETKENDEEFYKNKYSSKP--YKVDNMTRILPQQSRYISFIKDDRFVPVRKFKGnnGVVVLRDREPKEPVALIETV 920  baker's yeast
19113173 935 RDAVPASAdtePGEQEASPPEDFEYPFD 962  fission yeast
19073969     ----------------------------      Encephalitozoon cuniculi
730736   921 RQMKDVNA---PLPTPFKVDDNVDFPSA 945  baker's yeast
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