Conserved Protein Domain Family
TMEM107

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pfam14995: TMEM107 
Transmembrane protein
This family of proteins is found in eukaryotes. Proteins in this family are typically between 138 and 164 amino acids in length. There are two completely conserved residues (H and E) that may be functionally important and four transmembrane helices. The domains in this family vary in length from 124 to 126 amino acids. The precise function of the protein family is still unknown.
Statistics
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PSSM-Id: 464430
Aligned: 28 rows
Threshold Bit Score: 78.8283
Created: 26-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
EAX89882       8 LFPFRVLAFSAIYITVNVILYTLDSdyggeanivkNYYSArfsnsNLSpnlpdfiksaisrTLSSNEMIADaTTELRIWL 87 
EWS75294       8 IIPIKFVLIIFHLLVVTITIYSPIQ----------NIYAG-----IPAn-----------tPIGEKSFYTPaFNETQAVG 61 
EAX97468       8 IFPFRVFAFCSLYIVMNVVLFVIDKnesqqanpikNYYANrinnsVANpympdsfknsirgIFSSGKQIKHvQKQIKIWL 87 
EGD75563      35 LLRFRFALIACQCIIAIALTQRKEE----------HLLKH-----LPL-------------DDLDSPLHHRtYDGYVWTL 86 
EFO27997       3 ASSAYFVTIVAHGTMLVMALSEMNE----------YVMAT-----LPLt------------DWTEREYADV-ETSLTVAI 54 
CAS00706       7 TLTKYYQCLLGHFAMATIVIFDQTA----------HLEAS---------------------IIGGIPVAEEaRIGFTVCL 55 
NP_001252431   7 TCTKYFQCLMGHFALSTITIFSQAS----------HLEAS---------------------VSGGASISEEaRIGFTVCL 55 
Q583R6        28 LIPFRIFSILLYLTALICVAGSSDD----------FVLIEsr-----------------dnEVSGGGDRVDlRRSVNVYL 80  Trypanosoma brucei
CAM70018      31 LVPYRLAMWCVHFSTLICVTRGSDR----------MIRVSsl-----------------arGCAEADYVFL-RQVTNLCL 82 
Q4D1W7        28 LIPFRLLMMVVHFTALVCVSDGSDA----------MIRGGsl-----------------psNYMESEYRFL-RRATDGFL 79  Trypanosoma cruzi
EAX89882      88 IFADIFLVFLFISLIFGIVTTVAHLSFIEGVLHLIGVILMSHALFQNAHRNFVICGVFFGIMLPFLMELWQL 159
EWS75294      62 SINLLFLIIELCILVFGQNLFYDFFNSLQIFIHFIGAFLTTWYIIEGWNYRSLKYIFGVFTVIPMCLEFFPL 133
EAX97468      88 IVSDVLLALVFIFIILGFSTTSAPLSFIEGCLHFIGTVLISNTMLQPASSDYIICGVFFGVMAPFLLEIWEI 159
EGD75563      87 ---LLCNLAEFLLFFFGYSMFSQGCSLFSIVTHAGGVFFLAFFYAEQLFYPSLLFVILFSCGPPLLVSTWHF 155
EFO27997      55 SLGIACCVTEVVLLTFQLHTF--TKAIFSMCLHLLATIFLLKFIVDSHPLYHFWIVFGIFSVPAMLIACLNP 124
CAS00706      56 VLTMLGIIIEFVSIV--LEMPSVVRSLFATSSHTIATCLFLLFIYDAHPVSHFWILLVLLSAPSFFLALLSL 125
NP_001252431  56 VFTKLAILIEFASIL--VDLPSPSRSLYSTLSHTIASIFFLIFIYDSHPPAHFWLLFAFLSLPPCVLAVSAS 125
Q583R6        81 VVSFMLLFVTCWGIFTGRTLRSGTVNFMHCCSHTTAAIALIVIWCLKLHLHRMWHVFYAFGAIPTAMEVCAL 152 Trypanosoma brucei
CAM70018      83 ATSFLCLFFNLWGVLTTRTLRFGVDNWFQGSCHCAAAVLLIVSWQATVHVARIWQVFYIFSIIPTGIEAITL 154
Q4D1W7        80 AGSFLCLFFNVWGVVTARTLRSGLLNIMHGCFHAAAAVLLIVAWHMQERAERIWHVFYIFSVIPTGLEAIAL 151 Trypanosoma cruzi
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