5WTQ


Conserved Protein Domain Family
PAC4
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pfam16093: PAC4 (this model, PSSM-Id:406487 is obsolete and has been replaced by 465017)
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Proteasome assembly chaperone 4
PAC4 or proteasome assembly chaperone 4 protein promotes assembly of the 20S proteasome. It interacts with PSMG3. It associates with alpha subunits of the 20S proteasome. At the very C-terminal is a crucial HbYX or hydrophobic-tyrosine-X sequence motif that, in proteasome activators, opens the 20S proteasome entry pore.
Links
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Statistics
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PSSM-Id: 406487
Aligned: 115 rows
Threshold Bit Score: 31.3852
Created: 21-May-2020
Updated: 7-Aug-2020
Structure
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Program:
Drawing:
Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
5WTQ_A        33 VMRLTDSLFLWVGAT--PH--------------------------L--------------RNLAVAMSSry-dSiP-VST 68 
EFX01311      29 LTSRAKSLMVSVATTgtDEgdha-------------------rseL--------------GSFVYALPNryqaG-DpLCT 74  Grosmannia clav...
ERT02305      30 LTTRDKCLMLFVTTAgtEDget--------------------lapM--------------GSFVYAVPDrfklS-EpLCT 74  Sporothrix sche...
EPE09705      30 LTTRDKCIMLFVTSTasEDsea--------------------ltsL--------------GSFVYAVPDrfkpS-EpLCT 74  Ophiostoma pice...
EGX91482      27 VTTLDKAVMVSLTTAsqEElga--------------------ttpM--------------GSMVYALPDrfnpQ-QpLAT 71  Cordyceps milit...
EJT71221      28 LTVRSKSIMLCLTTAaaDEqgn--------------------pspM--------------GSFVYAIPDrfnkQ-QpLTT 72  Gaeumannomyces ...
EHA57224      36 LTVRPKSILLMVTTAsaDEatt--------------------ptpL--------------GSFVYAIPDrfnpS-QpLCT 80  Pyricularia ory...
XP_011108208  35 LTIEARHILLFLTTTsaNPsidlsilsipgvntssttggedvvnpMrggdsavprgkvgvGSFVYAMPSltnkK-EtIST 113 Dactylellina ha...
XP_002835593  25 LTLSKNHILLHLTTKtpEAasq--------------------patL--------------GSFVYALPPtgnhK-NpLST 69  Tuber melanospo...
CCX30421     328 LTIESHHVLLFLTSRapESppg--------------------saqL--------------GSFVYALKSttqpTp--LST 371 Pyronema omphal...

5WTQ_A        69 SLLGDT-SDTTSTGLAQRLARKTNKQVFVSYNL 100
EFX01311      75 TLYSDEkSLEFAVRLAKLIVRRTQMVAYVSTSI 107 Grosmannia clavigera kw1407
ERT02305      75 NIYVEEnSLEFAARLARLVVKRTQQPVYVSSSL 107 Sporothrix schenckii ATCC 58251
EPE09705      75 NIYIDEgSLEFAVRLAKLLVKRTQQPVYVSSSL 107 Ophiostoma piceae UAMH 11346
EGX91482      72 TIFTTQaTVEFTTRTARILARKANRPVYVTNSI 104 Cordyceps militaris CM01
EJT71221      73 PLYTVEpTLELTNRMARLVARRSGLPVCVTNSI 105 Gaeumannomyces tritici R3-111a-1
EHA57224      81 PLMTVEpTLEFATRLARLVAKRSGLPTYVGNSV 113 Pyricularia oryzae 70-15
XP_011108208 114 PLIPDMaTLETTERIARILARRLQVPVYLGNSM 146 Dactylellina haptotyla CBS 200.50
XP_002835593  70 AIYVREsTLETATRIAKILAKRTGLPVYVGNSM 102 Tuber melanosporum Mel28
CCX30421     372 PLYVREnTIETATLIARMVAAKTGLPTYVGCSI 404 Pyronema omphalodes CBS 100304
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