Conserved Protein Domain Family
DUF814
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pfam05670: DUF814 (this model, PSSM-Id:398994 is obsolete and has been replaced by 428576)
Domain of unknown function (DUF814)
This domain occurs in proteins that have been annotated as Fibronectin/fibrinogen binding protein by similarity. This annotation comes from Bacillus subtilis YloA, where the N-terminal region is involved in this activity. Hence the activity of this C-terminal domain is unknown. This domain contains a conserved motif D/E-X-W/Y-X-H that may be functionally important.
Links
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Statistics
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PSSM-Id: 398994
Aligned: 40 rows
Threshold Bit Score: 98.8335
Created: 20-May-2020
Updated: 7-Aug-2020
Structure
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Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
XP_005534898                  1 MPYVYDcdELQGYILFLGRDKYENDALLEYSLPL-DWWFHVDKHSSAHVYVRpkrrlfeLSETSggtayelsaaplEPPT 79   Cyanidioschyzon merolae strain 10D...
XP_012770199                549 KFHWFV--TSDGFLVLGGRDSTQNELLVKRYLTKgDLYFHADVHGGSSCILKn------PNGTA------------ESFP 608  Babesia bigemina...
KHN69476                    421 KFHFFF--SSDGTVVIGGKNSQQNEILVKKYLCDeDLYFHSGAHGCSSVIVK------------------------KESE 474  Ordospora colligata OC4...
OAG28884                    447 KFHWFV--TKDNDLIIAGRDAKQNEILVKKYLKEtDYYFHADIQGGSSVIAG---------K--------------DATE 501  Nematocida displodere...
EMR73228                     21 KFRWFI--SSDGNIVIAGKDAKNNELVVKKYLRNtDRYAHADVHGASSCVIKsk---diHDNKM------------LISE 83   Thermoplasmatales archaeon SCGC AB-539-N05...
Q8ZTG8                      407 KFHWTV--TTGRKPVIGGRDASQNEVVVKKYLKEhYLFFHADIPGASAVVAP--------PSED------------PLE- 463  Pyrobaculum aerophilum...
ODS40917                     73 KFRWFN--SSEGFLVIGGRDATTNEILIKKHTEKsDVVFHADVPGAPFFVIK--------TEGK------------EVTD 130  Candidatus Altiarchaeales archaeon WOR_SM1_SCG...
EOD42521                     68 KFRWMF--TTNNFLLIAGKDSITNEIIINKYLEKnDLVFHADIVGSPFGILK---------NGR------------NASE 124  Candidatus Nanobsidianus stetteri...
FidelitySystems:Mia14_0136   68 KFHWFF--TTGNLLAIGGRDAQQNELLNSKYFEDhDLFFHANIFGASVVILK---------DGL------------NASK 124  Candidatus Mancarchaeum acidiphilum...
WP_004079149                430 KFRWFY--TSDDVLVIGGRDAGTNEDIVRKYLEGkDTFLHADIHGGSAVAVK----------GE---------------T 482  Methanoplanus limicola...

XP_005534898                 80 EVVRAAAAVAKENSIE-GAKQsFVHVVYTPASNLLKSGD----MGPGQVGFRD 127  Cyanidioschyzon merolae st...
XP_012770199                609 NSIEEAACFAICLSSAwTQKM-VVPAWWVHHDQVSRSAPtgeyLPHGSFMIRG 660  Babesia bigemina
KHN69476                    475 NTIKEAAAMTLCMSSCwANGV-VSQIWYVYGNQVSKTPPsgeyLPKGSFAIKG 526  Ordospora colligata OC4
OAG28884                    502 ETKGTAASMAMCLSKTwEKGV-ISSVFSVRGDQVSKTAPageyLTQGSFMVSG 553  Nematocida displodere
EMR73228                     84 KTLDEACQFAASFSKAwRQ-FhETQAYWVLPEQVSKTPEsgeyLPKGSFIIRG 135  Thermoplasmatales archaeon...
Q8ZTG8                      464 --LLQIAQFAAAYSKAwKIGIhAVDVYYVKGVQVTKQPPsgqyLARGSFMIYG 514  Pyrobaculum aerophilum
ODS40917                    131 AAMKEAASGAASYSKAwSSGTgNCDVYYIASEQVSKSAGsgeyLTKGAFMIYG 183  Candidatus Altiarchaeales ...
EOD42521                    125 IDIYEAAKFVGSYSRAwKNKLsSIDVYYVYPDQVSKKAPsgmyLKKGSFMIYG 177  Candidatus Nanobsidianus s...
FidelitySystems:Mia14_0136  125 DDKEECAQFSASYSSAwNKMQgEVDVYCMRRDQVSKSTNkg-sLGTGSFLLKG 176  Candidatus Mancarchaeum ac...
WP_004079149                483 ECMDEAAVFAVSYSNAwKSGFySADVYAVPRDQVSKTAEsgesLKRGAFVIRG 535  Methanoplanus limicola
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