1Z7S,1VBB,1HRI,6SK7,3TN9,1BEV,1TMF,1MEC,1FMD,5OYI,1QQP,1D4M,6GZV,7C9Z,1OOP


Conserved Protein Domain Family
Rhv

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pfam00073: Rhv 
Click on image for an interactive view with Cn3D
picornavirus capsid protein
CAUTION: This alignment is very weak. It can not be generated by clustalw. If a representative set is used for a seed, many so-called members are not recognized. The family should probably be split up into sub-families. Capsid proteins of picornaviruses. Picornaviruses are non-enveloped plus-strand ssRNA animal viruses with icosahedral capsids. They include rhinovirus (common cold) and poliovirus. Common structure is an 8-stranded beta sandwich. Variations (one or two extra strands) occur.
Statistics
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PSSM-Id: 395026
Aligned: 49 rows
Threshold Bit Score: 113.946
Created: 21-Mar-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
1Z7S_2   24 TTQEAANAIVAYGEWPTYINDSEANPVDAPTEPDVSSNRFYTLESVSWKTTSRGW--WWKLPDclKDMGMFGQNMYYHYL 101  Coxsackievirus A21
P08292  612 PSDTMQTRHVHNYHSRSESSIENFLCRSACV--------IYIKYSSAESNNLKRYa-EWVINT--RQVAQLRRKMEMFTY 680  Coxsackievirus B4 (...
1OOP_A   44 PSDTMQTRHVKNYHSRSESTVENFLCRSACV---------FYTTYENHDSDGDNFa-YWVINT--RQVAQLRRKLEMFTY 111  Swine vesicular dis...
P03313  614 pgdtmqtrhvknyhsrSESTIENFLCRSACV---------YFTEYKN--SGAKRYa-EWVLTP--RQAAQLRRKLEFFTY 679  Coxsackievirus B3 (...
P03300  636 PSDTVQTRHVVQHRSRSESSIESFFARGACV-------TIMTVDNPASTTNKDKLfaVWKITY--KDTVQLRRKLEFFTY 706  Human poliovirus 1 ...
P22055  633 psdvvetrhVINYKTRSESCLESFFGRAACV-------TILSLTNSSKSGEEKKHfnIWNITY--TDTVQLRRKLEFFTY 703  Human coxsackieviru...
P36290  637 psdvietrhVVNYKTRSESTLESFFGRSACV----TMLEVENFNATTEADKKKQFt-TWAITY--TDTVQLRRKLEFFTY 709  Human coxsackieviru...
P03303  614 PSDSIETRTTYMHFNGSETDVECFLGRAACV--HVTEIQNKDATGIDNHREAKLFn-DWKINL--SSLVQLRKKLELFTY 688  rhinovirus B14
P07210  621 PEDMIETRYVITDQTRDETSIESFLGRSGCI---AMIEFNTSSDKTEHDKIGKGFk-TWKVSL--QEMAQIRRKYELFTY 694  Human rhinovirus 89...
P04936  614 PEDVIETRYVQTSQTRDEMSLESFLGRSGCIHESKLEVTLANYNKENFT--------VWAINL--QEMAQIRRKFELFTY 683  rhinovirus A2
1Z7S_2  102 GRSGYTIHVQCNA---------SKFHQGALGVFLIPEFVMacntesktsyvsyinaNPGERggeftntynpsntdasegr 172  Coxsackievirus A21
P08292  681 IRCDMELTFVITShqemstatnSDVPVQTHQIMYVPPGGP----------------VPTSVn------------------ 726  Coxsackievirus B4 (...
1OOP_A  112 ARFDLELTFVITStqeqptvrgQDAPVLTHQIMYVPPGGP----------------VPTKVn------------------ 157  Swine vesicular dis...
P03313  680 VRFDLELTFVITStqqpsttqnQDAQILTHQIMYVPPGGP----------------VPDKVd------------------ 725  Coxsackievirus B3 (...
P03300  707 SRFDMELTFVVTAnfte--tnnGHALNQVYQIMYVPPGAP----------------VPEKWd------------------ 750  Human poliovirus 1 ...
P22055  704 SRFDLEMTFVFTEnyps--tasGEVRNQCDQIMYIPPGAP----------------RPSSWd------------------ 747  Human coxsackieviru...
P36290  710 SRFDLEMTFVITEryyt--sntGYARNQVYQLMYIPPGAP----------------RPTAWd------------------ 753  Human coxsackieviru...
P03303  689 VRFDSEYTILATAsqp---dsaNYSSNLVVQAMYVPPGAP----------------NPKEWd------------------ 731  rhinovirus B14
P07210  695 TRFDSEITIVTAAaa-----qgNDSGHIVLQFMYVPPGAP----------------VPEKRd------------------ 735  Human rhinovirus 89...
P04936  684 TRFDSEITLVPCIsa-----lsQDIGHITMQYMYVPPGAP----------------VPNSRd------------------ 724  rhinovirus A2
1Z7S_2  173 kfaaldyllgsgVLAGNAFVYPHQIINLRtNNSATIVVPYVNSLVIDCMAKHN--NWGIVIL---------PLAPLAF 239  Coxsackievirus A21
P08292  727 ------------DYVWQTSTNPSIFWTEG-NAPPRMSIPFMSIGNAYTMFYDGwsNFSRDGIy--------GYNSLNN 783  Coxsackievirus B4 (st...
1OOP_A  158 ------------SYSWQTSTNPSVFWTEG-SAPPRMSVPFIGIGNAYSMFYDGwaRFDKQGTy--------GISTLNN 214  Swine vesicular disea...
P03313  726 ------------SYVWQTSTNPSVFWTEG-NAPPRMSIPFLSIGNAYSNFYDGwsEFSRNGVy--------GINTLNN 782  Coxsackievirus B3 (st...
P03300  751 ------------DYTWQTSSNPSIFYTYG-TAPARISVPYVGISNAYSHFYDGfsKVPLKDQ---------SAALGDS 806  Human poliovirus 1 Ma...
P22055  748 ------------DYTWQSSSNPSIFYMYG-NAPPRMSIPYVGIANAYSHFYDGfaRVPLEGEntdagdtfyGLVSIND 812  Human coxsackievirus ...
P36290  754 ------------DYTWQSSSNPSVFYTYG-SAPPRISIPYVGIANAYSHFYDGfaRVPLKDE---------TVDSGDT 809  Human coxsackievirus ...
P03303  732 ------------DYTWQSASNPSVFFKVG--DTSRFSVPYVGLASAYNCFYDGysHDDAETQy--------GITVLNH 787  rhinovirus B14
P07210  736 ------------DYTWQSGTNASVFWQEG-QPYPRFTIPFMSIASAYYMFYDGydGDSAASKy--------GSVVTND 792  Human rhinovirus 89 A...
P04936  725 ------------DYAWQSGTNASVFWQHG-QAYPRFSLPFLSVASAYYMFYDG---YDEQDQ--------------NY 772  rhinovirus A2
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