2VDU,3DXY,2FCA


Conserved Protein Domain Family
Methyltransf_4

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pfam02390: Methyltransf_4 
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Putative methyltransferase
This is a family of putative methyltransferases. The aligned region contains the GXGXG S-AdoMet binding site suggesting a putative methyltransferase activity.
Statistics
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PSSM-Id: 367068
Aligned: 17 rows
Threshold Bit Score: 184.801
Created: 21-Mar-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
2VDU_F  57 KKVTIADIGCGFGGLMIDLSPAFPEDLILGMEIRVQVTNYVEDRIIALrnntaskhGFQNINVLRGNA---MKFLPNFFE 133 baker's yeast
O66479  16 ipnleVEIGFGRGDFIVKLAKENPDKNFFGIEISQISIEKLMKRVGKK--------GLKNVYCTNVDAywgFYFL---FR 84  Aquifex aeolicus VF5
P44648  71 DNPVVLEIGFGMGKSLVDMAFANPDKNYLGIEVHTPGVGACIAYAVEK--------GVTNLRVICHDA---TEILRDSIA 139 Haemophilus influenza...
3DXY_A  34 EAPVTLEIGFGMGASLVAMAKDRPEQDFLGIEVHSPGVGACLASAHEE--------GLSNLRVMCHDA---VEVLHKMIP 102 Escherichia coli K-12
O83477  80 PAPLVVEIGFGMGSATAAIAARNPHLSYLGIEVYRAGIGRLLRKIEAE--------RLHNLRIIEHDA---LDVLRTMIA 148 Treponema pallidum su...
P9WFY9  76 DAPVVLEIGSGSGTSTLAMAKAEPHVDVIAVDVYRRGLAQLLCAIDKVg------sDGINIRLILGNA---VDVLQHLIA 146 Mycobacterium tubercu...
Q9CCZ9  55 STLVVLEVGCGSGTATLAMAQHEPDIDVIAVEVYRRGLAQLLCAIDRD--------QVHNIRMIHGNA---LYVLQYLIA 123 Mycobacterium leprae TN
O25443 118 QAPILIEIGFGSGRHLIELAKNNPTKTCLGIEIHTPSIAQALKQIELL--------DLKNLHILQGDG----RLVLESMP 185 Helicobacter pylori 2...
O84836  48 NGPICCELCSGNGDWVVEQALKDASVNWIAVEKRFDRVRKIWSKMGNY--------RVNNLLIVCGEA---QTFFSHYVS 116 Chlamydia trachomatis...
2FCA_A  38 DNPIHIEVGTGKGQFISGMAKQNPDINYIGIELFKSVIVTAVQKVKDS--------EAQNVKLLNIDA----DTLTDVFE 105 Bacillus subtilis
2VDU_F 134 KGQLSKMFFCFPDPHFKQRKHKARIITNTLLSEYAYVLKEGGVVYTITD---VKDLHEWMVKHLEEHPLFERLSKEWEEN 210 baker's yeast
O66479  85 DNYVENIYMNYPDPWFKKRHHKRRLTKPERLYMFAKKLKLGGEIRIRTDnyeFLEFTKESAKVLDCF----------EVE 154 Aquifex aeolicus VF5
P44648 140 DGALGGLQLFFPDPWHKAKHHKRRIVQPHFVTQVIQKLGENGFIHMATD---WENYAEQMLEVLSANTDLVNTSKNGDYI 216 Haemophilus influenza...
3DXY_A 103 DNSLRMVQLFFPDPWHKARHNKRRIVQVPFAELVKSKLQLGGVFHMATD---WEPYAEHMLEVMSSIDGYKNLSESNDYV 179 Escherichia coli K-12
O83477 149 PQTLAGLHIFFPDPWPKTRHHKRRLLYRPRTDLLARALAPGGYLYAVTD---WAEYARRAQEELARTPSLT-------WA 218 Treponema pallidum su...
P9WFY9 147 PDSLCGVRVFFPDPWPKARHHKRRLLQPATMALIADRLVPSGVLHAATD---HPGYAEHIAAAGDAEPRLVRVDPDTELL 223 Mycobacterium tubercu...
Q9CCZ9 124 PRSLTGVRVFFPDPWPKVRHHKRRFLQPATVELIADRLLPGGVLHTATD---HPDYAKQIAKFGDGEPLLSRADGRTQL- 199 Mycobacterium leprae TN
O25443 186 NHRCEKIFVHFPVPWNEKKH--RRVLSEKFLNEALRVLKPRGFLELRTD---DSLYFEDSLKLALKNFQCEIEIKKNAQI 260 Helicobacter pylori 2...
O84836 117 DASFQKIVVNFPDPWPKFRHRKHRLFQDLFVQDMMRTLVVGGQLTLATD---DYNYLVNAITVMLKY-----------LS 182 Chlamydia trachomatis...
2FCA_A 106 PGEVKRVYLNFSDPWPKKRHEKRRLTYSHFLKKYEEVMGKGGSIHFKTDnrgLFEYSLKSFSEYGLLLTYVSLDLHNSNL 185 Bacillus subtilis
2VDU_F 211 DECVKIMRNATE-------EGKKVERKKGDKFVA 237 baker's yeast
O66479 155 EGTLNVKEPLTK-------YEQKWLSMGKTLYKL 181 Aquifex aeolicus VF5
P44648 217 PRPD--FRPLTK-------FEARGYKLGHGVWDL 241 Haemophilus influenzae Rd KW20
3DXY_A 180 PRPA--SRPVTK-------FEQRGHRLGHGVWDL 204 Escherichia coli K-12
O83477 219 PQGARPWRPATE-------FERKAQTQGRAIHEL 245 Treponema pallidum subsp. pallidum str. Nichols
P9WFY9 224 --PISVVRPATK-------YERKAQLGGGAVIEL 248 Mycobacterium tuberculosis H37Rv
Q9CCZ9 200 --PISTVRPTTK-------YETKAQHAGNVVTEL 224 Mycobacterium leprae TN
O25443 261 P-------VVSK-------YEARWNKLKKDIYDL 280 Helicobacter pylori 26695
O84836 183 PGLKSPHYINVKdnyggswFENLWRSKGQEIFCT 216 Chlamydia trachomatis D/UW-3/CX
2FCA_A 186 EG-----NIMTE-------YEEKFSALGQPIYRA 207 Bacillus subtilis
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