Conserved Protein Domain Family
Vps55
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pfam04133: Vps55 (this model, PSSM-Id:398002 is obsolete and has been replaced by 427733)
Vacuolar protein sorting 55
Vps55 is involved in the secretion of the Golgi form of the soluble vacuolar carboxypeptidase Y, but not the trafficking of the membrane-bound vacuolar alkaline phosphatase. Both Vps55 and obesity receptor gene-related protein are important for functioning membrane trafficking to the vacuole/lysosome of eukaryotic cells.
Links
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Statistics
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PSSM-Id: 398002
Aligned: 114 rows
Threshold Bit Score: 57.9106
Created: 20-May-2020
Updated: 7-Aug-2020
Structure
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Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
EDK42066       7 IIFLSAFLASGFLLILLSCAL-------YN-N-YKPLWVIFIFLMAPLPNILANSiEAQR--DynfltfnDygnaqdlNL 75  Lodderomyces el...
EAY11791       7 yIVIGIFGTIALVLFIAGCAI-------TK-T-WWPLFGIIPATLSCIFGVSLSTkLGDDyve-------------dtEG 64  Trichomonas vag...
XP_001320939   7 yIVIGIFGTIALVLYIAGCAI-------TK-Q-WWPLFGIIPATLSCIFGISLSTkMGDDyve-------------dtEG 64  Trichomonas vag...
XP_001330722   6 yIILGIALTLGVTLIIVGCVT-------AK-N-AFALLELIPACVISFSYISYINkEDDSddD----------------- 59  Trichomonas vag...
EAY07081       7 yIALGVFLAIELALVIISCVL-------DK-N-AYALIIIVPLCFAIICQFLADSySDGYheE-------G--------- 61  Trichomonas vag...
XP_001565648   7 LIISAFCLVMGFLFLILGCTMv------KKrN-AWPLMSLVLYCFTPVPFVLCGRgAGSDefGgdd-depL--------- 69  Leishmania braz...
Q4Q9Q1         7 LIISAFFLVMGFLFLILGCTVv------KKrN-AWPLMSLAFYCFAPVPFFLCGRgADSDdfNdfd-depL--------- 69  Leishmania major
Q57ZB6         7 LVLSASLVVVAVVLSILACTVv------AGsN-VLPLFSLLLSFITPLPFLFFGRsESTFddD----------------- 62  Trypanosoma brucei
Q8MMD0         7 LFICAFLTCIGVTFLILACAV-------PTtKiFYPFFVLLFYVLSVLPVFIARRtTPGN------------------ET 61  fruit fly
EFC36584      11 LVAVAAGVSIGVMLAIIGCAVtwggvehPE-N-WFALITVLCYIIAPFPDIIARAfSSRFekEdp---edA--------- 76  Naegleria gruberi

EDK42066      76 --SPLQEFSKFVTGLLIVSGVALPLSLYHC-GLIQLELFLMSVSGGFIVYGDIILFMWFFSSEV 136 Lodderomyces elongisporus NRRL ...
EAY11791      65 cnIFTADSVLFYLVCSVVSTIALNVVFWHA-GTINKKCFGFMIGGDVAVCIGFVVFMILYGKTE 127 Trichomonas vaginalis G3
XP_001320939  65 cnIFTADSVLFYLLCSIVSCIALIAVFWHC-GTIDGICFGFMMGGDAATAIGLIAFIILWGKAe 127 Trichomonas vaginalis G3
XP_001330722  60 --VITKDFLIWLLTIAVVSIIALPCVLYHLeKIGKTVSLILDIIGCVAIFAGCIVVACLdredd 121 Trichomonas vaginalis G3
EAY07081      62 --LLTVDTINWFFGVAFAASIGIPLMLWHD-KLIKDIGLGLTLGAVVIQLISYWVFNCLKKKTD 122 Trichomonas vaginalis G3
XP_001565648  70 --DAFKTIGLFIGGVLLMSGPGLALVLYHT-SVICGSALLLTLLSGVCFLGATVSLTVTTTHEE 130 Leishmania braziliensis MHOM/BR...
Q4Q9Q1        70 --DAFSTVGLFMGGVLLISGPGLAVVLYHT-SVICGLALFFTLLSGVCFITAGVSLTVADrgng 130 Leishmania major
Q57ZB6        63 --GEINGFVVFLSGALAVSAPSLSIVLYHT-GYSSLGAFLLSLGSQVTLLGAAAFLQSGerqde 123 Trypanosoma brucei
Q8MMD0        62 --NPKSEFAHFLTAGMVLSAFALPIVLAHA-LVITWTASILTIISNIINYGTIFWYAMrddepy 122 fruit fly
EFC36584      77 --TVWEHFGAFLTSFIATIGLGLLFVLAHT-GIIQWETFAFEISGGIVIVATLFISFLVFTiak 137 Naegleria gruberi
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