3025043 37 GGMALGNPQLGLGVGLASQLILladMGGLYSVRLKTIFGAWVGAAIAMAVG-TIVPDGWGLG----LAITGFVLFASGYL 111 Synechocystis sp. P... 15834317 1 MTFEIPFVALSLAVLFYGIQS-----NAFYTKFVAILFVVATVLEIGSLFLiYKWSYGEPLIrliiAGPILMGCMFLMRT 75 Escherichia coli O1... 15793108 -------------------------------------------------------------------------------- Neisseria meningiti... 15676115 -------------------------------------------------------------------------------- Neisseria meningiti... 17548355 -------------------------------------------------------------------------------- Ralstonia solanacearum 16765390 -------------------------------------------------------------------------------- Salmonella typhimur... 16120944 1 --MIYGIPESAISCYLIIFVMK---PDGVESMVMAVAITILVSLVVGLVFLlIHFTLEAAPLrmaaLIVSSFLFLYLGSA 75 Yersinia pestis 15804673 1 MTFEIPFVALSLAVLFYGIQS-----NAFYTKFVAILFVVATVLEIGSLFLiYKWSYGEPLIrliiAGPILMGCMFLMRT 75 Escherichia coli O1... 2506684 -------------------------------------------------------------------------------- Escherichia coli 16131907 1 MTFEIPFVALSLAVLFYGIQS-----NAFYTKFVAILFVVATVLEIGSLFLiYKWSYGEPLIrliiAGPILMGCMFLMRT 75 Escherichia coli K12
3025043 112 AVYGEQGAMVGIVTTFAFLLGAqnvstDSFEFTSLAIGGMWSLILAIFiwpfrpnqPLrqmvanNYSILGNYLRAMAAAN 191 Synechocystis sp. P... 15834317 76 HRLGLVFFAVAIVAIYGQTFPA-----MLDYPEVVVRLTLWCIVVGLY--------PT------LLMTLIGVLWFPSRAI 136 Escherichia coli O1... 15793108 -------------------------------------------------------------------------------- Neisseria meningiti... 15676115 -------------------------------------------------------------------------------- Neisseria meningiti... 17548355 -------------------------------------------------------------------------------- Ralstonia solanacearum 16765390 -------------------------------------------------------------------------------- Salmonella typhimur... 16120944 76 SKLGPVGSIIALVIAYVMTLLS-----NIPMGEVATRGLLYAWLMAVS---------P--------MLLIIGFNLFFGRA 133 Yersinia pestis 15804673 76 HRLGLVFFAVAIVAIYGQTFPA-----MLDYPEVVVRLTLWCIVVGLY--------PT------LLMTLIGVLWFPSRAI 136 Escherichia coli O1... 2506684 -------------------------------------------------------------------------------- Escherichia coli 16131907 76 HRLGLVFFAVAIVAIYGQTFPA-----MLDYPEVVVRLTLWCIVVGLY--------PT------LLMTLIGVLWFPSRAI 136 Escherichia coli K12
3025043 192 FSPDDPQAQQLVVKLRQNLLKSRQTLVASQRGLWGQSKlrelLLVLIEHTERLNKCLMLLNEIVNfhnLPQLQTVEILME 271 Synechocystis sp. P... 15834317 137 SQMHQALN--DRLDDAIS--HLTDSLAPLPETRIEREA-------LALQKLNVFCLADDANWRTQs--AWWQSCVAT--V 201 Escherichia coli O1... 15793108 -------------------------------------------------------------------------------- Neisseria meningiti... 15676115 -------------------------------------------------------------------------------- Neisseria meningiti... 17548355 -------------------------------------------------------------------------------- Ralstonia solanacearum 16765390 -------------------------------------------------------------------------------- Salmonella typhimur... 16120944 134 PQTLLRASLAERLSTVAETLRYPNAANMARVGEQLQEG----QHEHQQRALFVRIFHLRPSAEAA-----WLESAVKSSY 204 Yersinia pestis 15804673 137 SQMHQALN--DRLDDAIS--HLTDSLAPLPETRIEREA-------LALQKLNVFCLADDANWRTQs--AWWQSCVAT--V 201 Escherichia coli O1... 2506684 -------------------------------------------------------------------------------- Escherichia coli 16131907 137 SQMHQALN--DRLDDAIS--HLTDSLAPLPETRIEREA-------LALQKLNVFCLADDANWRTQn--AWWQSCVAT--V 201 Escherichia coli K12
3025043 272 DAFNALGEVCLDLGQMVLGKRRIPNtnrlqllvqaLQQQKKLQRQALTEDFNDynsltTVTQLVNHLENLIKQLEQTIQT 351 Synechocystis sp. P... 15834317 202 --TYIYSTLNRYDPTSFADSQAIIEfrqkl-aseiNKLQHAITEGQCWQSDWRi---sESEAMAARECNLENICQTLL-Q 274 Escherichia coli O1... 15793108 -------------------------------------------------------------------------------- Neisseria meningiti... 15676115 -------------------------------------------------------------------------------- Neisseria meningiti... 17548355 1 --------------------------------------------------------------------------MSISIS 6 Ralstonia solanacearum 16765390 -------------------------------------------------------------------------------- Salmonella typhimur... 16120944 205 RLLLVTSALPPTSPEAVRLELAAYCs----------DAAQAIASGDLAAP---------PHFAIEDTSDEINEIRNALIA 265 Yersinia pestis 15804673 202 --TYIYSTLNRYDPTSFADSQAIIEfrqkl-aseiNKLQHAITEGQCWQSDWRi---sESEAMAARECNLENICQTLL-Q 274 Escherichia coli O1... 2506684 -------------------------------------------------------------------------------- Escherichia coli 16131907 202 --TYIYSTLNRYDPTSFADSQAIIEfrqkl-aseiNKLQHAVAEGQCWQSDWRi---sESEAMAARECNLENICQTLL-Q 274 Escherichia coli K12
3025043 352 AELLQNPQLfsdnnsndqgKLNKVRLMPWWDPlgsnFHLNSPLLRHGLRMALGGMVGATIAHLTQIPYGFWIVITLIFVL 431 Synechocystis sp. P... 15834317 275 LGQMDPNTP----------PTPAAKPPSMVAD----AFTNPDYMRYAVKTLLACLICYTFYSGVDWEGIHTCMLTCVIVA 340 Escherichia coli O1... 15793108 1 ----------------mntSQRNRLVSRWLNSy---ERYRYRRLIHAVRLGGAVLFATASARLLHLQHGEWIGMTVFVVL 61 Neisseria meningiti... 15676115 1 ----------------mntSQRNRLVSRWLNSy---ERYRYRRLIHAVRLGGAVLFATASARLLHLQHGEWIGMTVFVVL 61 Neisseria meningiti... 17548355 7 LPRAPKLPAp--------lLYALRLVRDPHR------RYRYARYIHGTRVGLGVLLSIAVTSGLGWPHGEWATISLLIVI 72 Ralstonia solanacearum 16765390 1 -------------------MRADKSLSPFEIR-----LYRHYRIVHGIRIALAFILTFLLVRLFSIPEGTWPLITLVVIM 56 Salmonella typhimur... 16120944 266 LANADNGQD-----------LDAPKSSFFAAD----ALTNPVHQQFALKTTAAALICYLIYTALDWQDIHTAMITCYVAA 330 Yersinia pestis 15804673 275 LGQMDPNTP----------PTPAAKPPSMVAD----AFTNPDYMRYAVKTLLACLICYTFYSGVDWEGIHTCMLTCVIVA 340 Escherichia coli O1... 2506684 1 -------------------MRADKSLSPFEIR-----VYRHYRIVHGTRVALAFLLTFLIIRLFTIPESTWPLVTMVVIM 56 Escherichia coli 16131907 275 LGQMDPNTP----------PTPAAKPPSMAAD----AFTNPDYMRYAVKTLLACLICYTFYSGVDWEGIHTCMLTCVIVA 340 Escherichia coli K12
3025043 432 KPD--FSLTFQRLSNRLLGTFLGVLVMSIALKLIQDPQL-----LSWLGILAIAMGMALLRFH----YSVAVFFITAFAL 500 Synechocystis sp. P... 15834317 341 NPN--VGSSYQKMVLRFGGAFCGAILALLFTLLVMPWLDni-veLLFVLAPIFLLGAWIATSSerssYIGTQMVVTFALA 417 Escherichia coli O1... 15793108 62 GMLqfQGAIYSKAVERMLGTVIGLGAGLGVLWLNQHYFHgnllfYLTVGTASALA-GWAAVGK----NGYVPMLAGLTMC 136 Neisseria meningiti... 15676115 62 GMLqfQGAIYSKAVERMLGTVIGLGAGLGVLWLNQHYFHgnllfYLTVGTASALA-GWAAVGK----NGYVPMLAGLTMC 136 Neisseria meningiti... 17548355 73 AGLqhHGNIRKRAAERAWGTLIGALAGLLLIVQQTYLGHpp--lTYALMGIACGICAYHAIGK----GGYIALLAAITLV 146 Ralstonia solanacearum 16765390 57 GPIsfWGNVVPRAFERIGGTILGAALGLVALRLELFSLPl---mLVWCAIAMFLC-GWLALGK----KPYQALLIGITLA 128 Salmonella typhimur... 16120944 331 LGT--TGETVHKLVLRIIGCLIGALMGVLSIIFIIPHMSdi-gqLMALVFGCILVAAWVSCGS----ERIAYAGVQVGLA 403 Yersinia pestis 15804673 341 NPN--VGSSYQKMVLRFGGAFCGAILALLFTLLVMPWLDni-veLLFVLAPIFLLGAWIATSSerssYIGTQMVVTFALA 417 Escherichia coli O1... 2506684 57 GPIsfWGNVVPRAFERIGGTVLGSILGLIALQLELISLPl---mLVWCAAAMFLC-GWLALGK----KPYQGLLIGVTLA 128 Escherichia coli 16131907 341 NPN--VGSSYQKMVLRFGGAFCGAILALLFTLLVMPWLDni-veLLFVLAPIFLLGAWIATSSerssYIGTQMVVTFALA 417 Escherichia coli K12
3025043 501 ILKAIDPSvPTEYALLSR--LVCTLIGSAIALGLAFSFLRQSENLRFTQASVRMLTNLEQYFQQLIPALLGKEsinkkea 578 Synechocystis sp. P... 15834317 418 TLENVFG--PVYDLVEIRdrALGIIIGTVVSAVIYTFVWPESEARTLPQKLAGALGMLSKVMRIPRQQEVTALrt----y 491 Escherichia coli O1... 15793108 137 MLIGDNGS-EWFDSGLMR--AMNVLIGAAIAIAAAK-LLPLKSTLMWRFMLADNLTDCSKMIAEISNGRRMTRerl--ee 210 Neisseria meningiti... 15676115 137 MLIGDNGS-EWLDSGLMR--AMNVLIGAAIAIAAAK-LLPLKSTLMWRFMLADNLADCSKMIAEISNGRRMTRerl--ee 210 Neisseria meningiti... 17548355 147 IVVG-HGD-NDLLDGAWR--TLNVLVGIAIALLFSF-ALPLYATYSWRYRLADALRECAKVYASLSKAGATAG------- 214 Ralstonia solanacearum 16765390 129 VVVG-APA-GDMDTALWR--GGDVILGSLLAMLFTG-IWPQRAFLHWRIQLAHCVTAYNRVYQAALSPNLLERprl---- 199 Salmonella typhimur... 16120944 404 FLLTVLQG-FGPSTDMGV--ALDRVLGILLGNLVVYLIFSRLWPVAITDAVHVHISRALKGLTNLAALSPDAR------- 473 Yersinia pestis 15804673 418 TLENVFG--PVYDLVEIRdrALGIIIGTVVSAVIYTFVWPESEARTLPQKLAGALGMLSKVMRIPRQQEVTALrt----y 491 Escherichia coli O1... 2506684 129 IVVG-SPT-GEIDTALWR--SGDVILGSLLAMLFTG-IWPQRAFIHWRIQLAKSLTEYNRVYQSAFSPNLLERprl---- 199 Escherichia coli 16131907 418 TLENVFG--PVYDLVEIRdrALGIIIGTVVSAVIYTFVWPESEARTLPQKLAGTLGMLSKVMRIPRQQEVTALrt----y 491 Escherichia coli K12
3025043 579 eRvRNETRLAATAMQIALDRLLS-DPSTPLEKQEPALTMTNYLARLSRGFRVLISHLENssgs----npppPIKLFTEQV 653 Synechocystis sp. P... 15834317 492 lQiRIGLHAAFNACEEMCQRVAL-ER---QLDSEERALLIERSQTVIHQGRDLLHAWDAt----------wNSAQALDNA 557 Escherichia coli O1... 15793108 211 nMaKMRQINARMVKSRSHLAATS-GESRISPAMMEAMQHAHRKIVNTTELLLTTAAKLQspklngseirllDRHFTLLQT 289 Neisseria meningiti... 15676115 211 nMaKMRQINARMVKSRSHLAATS-GESRISPAMMEAMQHAHRKIVNTTELLLTTAAKLQspklngseirllDRHFTLLQT 289 Neisseria meningiti... 17548355 215 -SePLKHLNRLNALLVQLRSLMPsVSKEIEVPIERLERIQHSLRICISTLELLGTARASa-----------DAPAARATA 282 Ralstonia solanacearum 16765390 200 -dkHLQRLLNDVVKMRGLITPAS-KETRIQKSIFEAIQTINRNLVCMLELQINAHWATRashf-----vmlNAHTLRETQ 272 Salmonella typhimur... 16120944 474 ---PAALREATTVEAEITKAQEE-----LALIPFEPVQFRPSRKECARLQAILAEMGK-------------LCPVLFLPT 532 Yersinia pestis 15804673 492 lQiRIGLHAAFNACEEMCQRVAL-ER---QLDSEERALLIERSQTVIHQGRDLLHAWDAt----------wNSAQALDNA 557 Escherichia coli O1... 2506684 200 -esHLQKLLTDAVKMRGLIAPAS-KETRIPKSIYEGIQTINRNLVCMLELQINAYWATRpshf-----vllNAQKLRDTQ 272 Escherichia coli 16131907 492 lQiRIGLHAAFNACEEMCQRVAL-ER---QLDSEERALLIERSQTVIRQGRDLLHAWDAt----------wNSAQALDNA 557 Escherichia coli K12
3025043 654 QQSLENlrFSLEHQSSPAALPPMATTIKEireyhqsyqaqRITEINQKQdftptRRYLDDFNLVVEECQQIYQRLETIHS 733 Synechocystis sp. P... 15834317 558 LQPDKa--GQFADALEKYAAGLATALSRS-----------PQITLEETP------ASQAILPTLLKQEQHVCQLFARLPD 618 Escherichia coli O1... 15793108 290 DLQQTValINGRHARRIRIDTAINPELEA-----------LAEHLHYQWqg-flWLSTNMRQEISALVILLQRTRRKWLD 357 Neisseria meningiti... 15676115 290 DLQQTValINGRHARRIRIDTAINPELEA-----------LAEHLHYQWqg-flWLSTNMRQEISALVILLQRTRRKWLD 357 Neisseria meningiti... 17548355 283 DILSAQedRRIRDTLIGISRALRFGTVAR-----------LAHSRAADA-----EPAASLPGQLTAESALALRFASEVEQ 346 Ralstonia solanacearum 16765390 273 QMTQQTllT-IAHALFEGNPQPVLANTGK-----------LNDIAAELRq-----LMNEQQGDAVAETPIHGYVWLSMET 335 Salmonella typhimur... 16120944 533 EKSAS-----DVEQLR-----QLSAGSDA-----------MTLSDEQGQ------NSGSLRQELSPINLTIQQRIKRLEE 585 Yersinia pestis 15804673 558 LQPDKa--GQFADALEKYAAGLATALSRS-----------PQITLEETP------ASQAILPTLLKQEQHVCQLFARLPD 618 Escherichia coli O1... 2506684 273 HMMQQIllS-LVHALYEGNPQPVFANTEK-----------LNDAVEELRq-----LLNNHHDLKVVETPIYGYVWLNMET 335 Escherichia coli 16131907 558 LQPDRa--GQFADALEKYAAGLATALSRS-----------PQITLEETP------ASQAILPTLLKQEQHVCQLFARLPD 618 Escherichia coli K12
3025043 734 AIARFTDSPQLANG 747 Synechocystis sp. PCC 6803 15834317 619 WTAPALTPATEQAQ 632 Escherichia coli O157:H7 15793108 358 AHERQHLRQSLLET 371 Neisseria meningitidis Z2491 15676115 358 AHERQHLRQSLLET 371 Neisseria meningitidis MC58 17548355 347 LRSEFLATAPRWNI 360 Ralstonia solanacearum 16765390 336 ARQLELLSHLICRA 349 Salmonella typhimurium LT2 16120944 586 LLGI---------- 589 Yersinia pestis 15804673 619 WTAPALTPATEQAQ 632 Escherichia coli O157:H7 EDL933 2506684 336 AHQLELLSNLICRA 349 Escherichia coli 16131907 619 WTAPALTPATEQAQ 632 Escherichia coli K12
Jiyao W et al.(2023). "The conserved domain database in 2023.",