1VLL,2I99


Conserved Protein Domain Family
OCD_Mu_crystall
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pfam02423: OCD_Mu_crystall (this model, PSSM-Id:396818 is obsolete and has been replaced by 426766)
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Ornithine cyclodeaminase/mu-crystallin family
This family contains the bacterial Ornithine cyclodeaminase enzyme EC:4.3.1.12, which catalyzes the deamination of ornithine to proline. This family also contains mu-Crystallin the major component of the eye lens in several Australian marsupials, mRNA for this protein has also been found in human retina.
Links
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Statistics
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PSSM-Id: 396818
Aligned: 8 rows
Threshold Bit Score: 398.355
Created: 20-May-2020
Updated: 7-Aug-2020
Structure
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Program:
Drawing:
Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
1VLL_B               14 ETLILTQEEVESLISMD-EAMNAVEEAFRLYALG---KAQMPPKVYLEFEK---GDLRAMPAHLMG---YAGLKWVNSHP 83  Archaeog...
P55665                3 TMKILTEGELRQIVPLDlDAVKCTEDAFRALAVPn--AVKMPPILRLDVPDs-rGEVDVKTAYIPGl-gGFAIKISPGFF 78  Sinorhiz...
O27539               12 KTVVLTRSDVEGLLNMD-DCLKAVEGAFVQEALG---RVQMPPKMYLFFRRy-nGDLRVMPSYLEEl-eMAGVKCVNVHP 85  Methanot...
rhodo:RCAP_rcc02113  19 ENMMRLVHAIGVERFIA-DLAGHIEADFRRWPE-----FDKTPRVASHSRD---GVIELMPTADAE---SYGFKYVNGHP 86  Rhodobac...
P09773               16 ENMMDLAVSTGIENFLV-QLAGYIEEDFRRWES-----FDKIPRIASHSRD---GVIELMPTSDGT---LYGFKYVNGHP 83  Agrobact...
Q2YIG4               15 DHMMKLVLRVGVETFLK-ELAGYVEEDFRRWQN-----FDKTPRVASHSKE---GVIELMPTSDGT---LYGFKYVNGHP 82  Brucella...
2I99_B                3 VPAFLSAAEVEEHLRSSsLLIPPLETALANFSSGpegGVMQPVRTVVPVTKh-rGYLGVMPAYSAAe-dALTTKLVTFYE 80  human
WP_074493647         26 VKDVAQCVDVMEETLVLlAQGDYKMAGLNSNSHGamiTFPENPEFEGMPKDgpdRRFMAMPAYLGGrfkNTGVKWYGSNA 105 Coryneba...

1VLL_B               84 GNPDK-GLPTVMALMILNSPETG-FPLAVMDATYTTSLRTGAAGGIAAKYLARKNSSVFGFIGCGTQAYFQLEALRRVFD 161 Archaeog...
P55665               79 DNPKI-GLPSTNGMMVLLSSQTGlVQALLLDNGYLTDVRTAAAGAVAAKHLSQQDASVATIFGAGVQARLQLRALTLVRP 157 Sinorhiz...
O27539               86 SNPDRhSLPTVMAVIELVDPETG-FPIALMDGTHITDMRTGAAGGVSVKYLASRDASRLGIIGAGRQAWTQLMAISRVAD 164 Methanot...
rhodo:RCAP_rcc02113  87 GNMRA-GYQTVTAFGVLSSVSTG-YPLLLTEMTLLTALRTAATSALVGRYLAPEGAQVMALIGNGAQCEFQALAFRALCG 164 Rhodobac...
P09773               84 KNTKS-GRQTVTAFGVLSDVDSG-YPLLLSEMTILTALRTAATSAIAAKYLARKDSRTMALIGNGAQSEFQALAFKALIG 161 Agrobact...
Q2YIG4               83 KNTRD-GLQTVTAFGVLADVGSG-YPMLLTEMTILTALRTAATSAVAAKHLAPKNARTMAIIGNGAQSEFQALAFKAILG 160 Brucella...
2I99_B               81 DRGITsVVPSHQATVLLFEPSNG-TLLAVMDGNVITAKRTAAVSAIATKFLKPPSSEVLCILGAGVQAYSHYEIFTEQFS 159 human
WP_074493647        106 ENKAS-GLPRSIHTFVLNDTVTG-APKAIMSANLLSAYRTGAVPGVGVKHLAVADATTLAVVGPGVMAKTITEACIAERP 183 Coryneba...

1VLL_B              162 -IGEVKAYDVREKAAKKFVSYCE----DRGISASVQPAEEASRCDVLVTTTPSRK------PVVKAEWVEEGTHINAIGA 230 Archaeog...
P55665              158 -IRQARIWARDQLKAEALVEQLKle-hSFAISASDDPRQAVSGAHIVVTTTPADR------PILVASWLEAGQHVTAMGS 229 Sinorhiz...
O27539              165 -LEEVSVYCRTPSTREKFALRASke-yEVPVRAATDPREAVEGMDIVVTVTPSRS------PVVMADWVSPGTHICAMGA 236 Methanot...
rhodo:RCAP_rcc02113 165 -INRLRLYDIDPRATEKALRNLRa--qGFEVTACASTQTAVEGAQILTTCTADKQf----aTILTDNMVGAGVHLNAIGG 237 Rhodobac...
P09773              162 -VDRIRLYDIDPEATARCSRNLQr--fGFQIEACTSAEQAVEGADIITTATADKHn----aTILSDNMIGPGVHINGVGG 234 Agrobact...
Q2YIG4              161 -VDKLRLYDLDPQATAKCIRNLQg--aGFNIVACKSVEEAVEGADIITTVTADKAn----aTILTDNMVGAGVHINAVGG 233 Brucella...
2I99_B              160 -FKEVRIWNRTKENAEKFADTVQg-----EVRVCSSVQEAVAGADVIITVTLATE------PILFGEWVKPGAHINAVGA 227 human
WP_074493647        184 gITTIKIKGRSERGINAFATWALekfpEIEVVAVGSEEDVVKDADIVIAATTTDAagssafPYFKKEWLKPGALLLLPAA 263 Coryneba...

1VLL_B              231 DGPGKQELDVEILKKAKIVV-DDLEQAKHGGEINVAVS-----------KGVIGVEDVHATIGEVIAGLKDGRESDEEIT 298 Archaeog...
P55665              230 DAEHKNELDPAAIARADVYVaDSLTQTRRLGELHHAIE-----------AGLIARDAAFPELGEVIAGVKTGRTRESDIT 298 Sinorhiz...
O27539              237 DAPGKQELDPLILKNARVFY-DSLEQATHSGEINVPIT-----------EGILRVDDLQGSLGDVMTGKIEGRTSPADVT 304 Methanot...
rhodo:RCAP_rcc02113 238 DCPGKTELHPDILKRADIFV-EYPPQTRIEGEIQQ-----------------LDPDHPVIELWQVMRGEVPGRRDARQIT 299 Rhodobac...
P09773              235 DCPGKTEMHRDILLRSDIFV-EFPPQTRIEGEIQQ-----------------LAPDHPVTELWRVMTGQDVGRKSDKQIT 296 Agrobact...
Q2YIG4              234 DCSGKTELHGDILRRSDIFV-EYPPQTRIEGEIQQ-----------------LPEDYPVNELWEVITGRIAGRKDARQIT 295 Brucella...
2I99_B              228 SRPDWRELDDELMKEAVLYVdSQEAALKESGDVLL------------------SGAEIFAELGEVIKGVKP--AHCEKTT 287 human
WP_074493647        264 GRFDDAYLLDDARLVVDYMG-LYEAWAEEYGPQAYQLLgipgthwydlaLQGKLDLAKISQIGDICSGKLPGRTNDEEII 342 Coryneba...

1VLL_B              299 IFDSTGLAIQDVAVAKVVYENALSKN 324 Archaeoglobus fulgidus DSM 4304
P55665              299 IADLTGTGVQDTAIATLAFQRAEERS 324 Sinorhizobium fredii NGR234
O27539              305 VFDSTGLSIQDITTAWMIYERAVAGE 330 Methanothermobacter thermautotrophicus str. Delta H
rhodo:RCAP_rcc02113 300 LFDSVGFAIEDFSALRFVHERIRGtd 325 Rhodobacter capsulatus SB 1003
P09773              297 LFDSVGFAIEDFSALRYVRDRVEGSS 322 Agrobacterium fabrum str. C58
Q2YIG4              296 LFDSVGFATEDFSALRYVRDKLKDTg 321 Brucella abortus 2308
2I99_B              288 VFKSLGMAVEDTVAAKLIYDSWSSG- 312 human
WP_074493647        343 LYSVGGMPVEDVAWATQVYENALEKG 368 Corynebacterium glutamicum
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