Conserved Protein Domain Family
SfcA

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COG0281: SfcA 
Malic enzyme [Energy production and conversion]
Malic enzyme is part of the Pathway/BioSystem: Urea cycle
Statistics
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PSSM-Id: 440050
Aligned: 893 rows
Threshold Bit Score: 273.424
Created: 9-Feb-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
YP_169914     36 LnkdvafsqeErvafdligylpekvesLeEQairvrrqldlkpNSLEKYVFlnrlhDLNTTLFYHFVRENLEEIMPIIYT 115
AKV00873      37 tnkgsafteaerkelglegllpaatesIeRQlervlghlavkpNDLERYIYlidlcDRDETLFYRTIMSDPARFVPIVYD 116
WP_014403325  17 YnkdtafsaaEreafgleglvppaidtLeRQlervghhldaksSDLEQYIYlmslaGRNETLFYKTLMSDPARFVPIVYD 96 
APR76012      24 RnkgtaftneErraeglegllpyavesLdRQvervmqhleakpNDLERYIYliglaDRNETLFYRTVMSDPARFVPILYD 103
WP_081434091  31 QnkgtafsrdErqalglegllphavesLdRQvervlshldtkmDDLERYIYligleDRNETVFYKTIMSDPKRFIPILYD 110
WP_012812311  20 LnkgtafteeErrlyglegllptqvenLdRQverihrhleakpSNLERYIYlsglrDQNETLFYKVLMSNPARFVPIVYA 99 
WP_050726768  16 LtkstaftakEreslglvgllpdavedEdLQirrvhqqlghknTDLDRYIYlnallDHDETLFYKVLMSDPAHFLPIVYD 95 
WP_025439986  18 LnketaftmtErqslglegllpptvenIdRQlervqtqlaakpNDLERYIYlmslaARNKTLFYHTLMSDPARFVPIVYD 97 
WP_012225053  20 FnrgtaftaaErqtyglegllppqietLeRQaeralrhldakpTDLERYIYlaalvDRNETLFYKVLMSDPARFVPIVYA 99 
WP_013581457  15 EnrgtafnqaEreekglvgllppvvetLeNQvkrclyqlskknNDLEQYIYlaqlaDDNQTLFFAVLATDPARFLKIVYD 94 
YP_169914    116 PTVGEAVQKYSSSFRKQSglfisishkkhiarilerYEYNSIDLVLVTDGEAVLGIGDQGIGGMNISIGKIMVYVAASGI 195
AKV00873     117 PTIAEACLKFGHIYRRARgmyvtramkgrmrevlrnWPFDDVRFICVSSGGRILGLGDIGANGMPIPIGKLQLYTACAAV 196
WP_014403325  97 PTVAYACLAFGHIFRHSSgmyltrdmkerylevfrnWPVKDVRFICVSTGGRILGLGDIGANGMGIPIGKLQLYTACAAV 176
APR76012     104 PTVAEACLVFGHIYRRASgmyvtrlmkgriaevlrnWPTRDVRFICVSTGGRILGLGDIGANGMGIPIGKLQLYTACAAV 183
WP_081434091 111 PTVADACLTFGNLYRRARgmyitrhmkgriaevlrnWPRKDVRFICVSTGGRILGLGDIGANGMGIPIGKLQLYTACAAV 190
WP_012812311 100 PTLAAVCQQFSHIYRRPRgmyisldmrgrikdvlqnWPMDNVRFMCVTTGGRILGLGDIGVNGMGIPIGKLDLYTACGAV 179
WP_050726768  96 PTIAEACLKFGHIYRGPRgmylslsrkghvrdvlrnWPEKDVRVICVTDGGRILGLGDIGANGMGIPIGKLQLYTATAAV 175
WP_025439986  98 PTVADACLTFGHIYRGSAgmyltrdmkgrfkkilrnWPVKDVRFICVSTGGRILGLGDIGANGMGIPIGKLQLYTACAGV 177
WP_012225053 100 PTLGEACKAFSHIYRRPRgmyislemkgriadilrnWPVSDVRFICVTTGGRILGLGDIGANGMGIPIGKLQLYTACGAV 179
WP_013581457  95 PTVGTACLEFGHIYRKPNgmylsmdqrgklkevlknWPVGDVRVICVSTGGRILGLGDLGTNGMGIPIGKLQLYTACAAV 174
YP_169914    196 DparVLPVQLDmgTNNdallnapgylgvrlprvsgetydefIEEFVTQVKARFPNVFLHWEDLGRDNATRILEKYKDKLC 275
AKV00873     197 PpdgLLPILFDigTTNeslrndplylglrevppgdqevdalVDEFVAAVQEVFPGCCIHFEDWKGTDAIRLLERYRDKIL 276
WP_014403325 177 PpesLLPVLLDigTTNaplradplylglrqpppeddevdaiADAFVAAANEAFPGVCIHFEDWKGVDAMRLLDRYRDKIL 256
APR76012     184 PpdcLLPMLLDigTTNaalradplylglrelpppeqkldelVDELVQAVQQVFPGCCIHFEDWKGTDAIRLLARYEHKVL 263
WP_081434091 191 PpdcLLPVLFDigTTNeslradpfylgtrepplaeaeldelTEEFITAVQEVFPDCCVHFEDWKGTDAIRMLDRYRDRIL 270
WP_012812311 180 PpdsLLPVQLDigTTNsalradplylglrrepppieeldsfVEEFIEAVQEVFPQSCIHFEDWKGTDALRYLKKYHDRVL 259
WP_050726768 176 PprvLLPAFLDagTNNdellhdplylglrrtrprteelyefVDEFVSAVQDVFPLCCIHFEDWTGVDAVHLLKRYRDKVC 255
WP_025439986 178 PpeaLLPVLLDigTTNaalradplylglrelppdeaevdliSDAFIEAATDVFPGVCIHFEDWKGTDAMRLLARYRDKVL 257
WP_012225053 180 PpqvTLPIQLDigTTNaalradplylglrhepppqaeldafVEEFVTAVQEVFPACCIHFEDWKGTDAIRYLERYRERVL 259
WP_013581457 175 QpdvLLPVLLDcgTDNekllndplylglkqkrpttdeldafVQEFVDAVQERFPKCCIHFEDWKGTDALRLLARYVTEIS 254
YP_169914    276 TFNDDIEGTGIVATANCIAGVKTASTIrinageitveealsgICDIKVVIFGAGSAGCGIARQLADViadraGVSIekar 355
AKV00873     277 CYNDDIQGTASVAIAGLTTALQIIGAK---------------LSDQRILFVGAGSAGIGIANMIVEAtv-aeGLSReaar 340
WP_014403325 257 CYNDDIQGTASVVIAGLTTAMQIKREK---------------LTDQRFLFLGAGSAGLGISNMIVSAlv-qqGLSEeear 320
APR76012     264 CYNDDIQGTAGVTLAGLTTALEIVGAP---------------LTQQRILFLGAGSAAIGIAGLLASAme-leGLSReaar 327
WP_081434091 271 TYNDDIQGTASVALAGIAAAMNITGGK---------------LSEQRVLFLGAGSAGIGISKLIAAEmq-tkGLTAeear 334
WP_012812311 260 CYNDDIQGTAAVTLAGLITALKIKNES---------------LTQQRFLFLGAGSSGIGTADMLVSAlk-qeGLSEqeai 323
WP_050726768 256 CYNDDIQGTAAVTLAGLMNAVRIKGSK---------------LSEERILFLGAGSAGIGIADLVASAmr-qeGLSEeear 319
WP_025439986 258 CYNDDIQGTAAIAVAGLTTALQIKNET---------------FADQRVLFLGAGSAGIGIASMIVSAmv-eaGLGEaear 321
WP_012225053 260 CYNDDIQGTASVTLAGLVTALRIKGEK---------------LSDQTVLFLGAGSSALGTSDLLVKAmq-aeGLSQadar 323
WP_013581457 255 CYNDDIQGTGSVTVAGLYNAMKISKGD---------------LKDQRVLFFGAGSAGIGIANMIASAmk-leGLSErear 318
YP_169914    356 SSIYLVDRYGLVCDRLraKRITPEQKLFVKTREEidkwkvedfnyiTLEETVKNTkcDILIGTSgQPGSFTKEIIKTMAk 435
AKV00873     341 ERISMFDVNGLLVSSR--ADLSSSQRGYARELGAm----------tDLQKVVETVkpSVLIGVStKGGVFTQAVVETMAa 408
WP_014403325 321 ERIWLMDSKGLIESGR--QDINRWKRRFAHEAKAs----------tSLLEVVKTFkpSVLIGVStCGGLFTDEVIKEMAr 388
APR76012     328 KRISMFDVDGLLEPSR--TDLSDTQRLYAHEAKPs----------kDLVETIAALkpTVLIGVStTGGAFTQRVVETMSr 395
WP_081434091 335 ARIALFDVNGLVEASR--TDLTEAQKLYAHKGPPt----------kDFVKFIKEFkpTVLIGVStKAGAFNQQVVEAMSq 402
WP_012812311 324 DRITLMDVNGLLETSR--TDLLPEQERFAKDLPPs----------rDLLGMIKTVkpTVLIGVStAGGSFTQEVVEEMSk 391
WP_050726768 320 GRISLFDIHGLIESSR--KDLEDFQKPYAHSMKPt----------kDFVEAIEAFkpTAIIGVStVGKAFNKKVVEAMGr 387
WP_025439986 322 ERIVLIDVNGLIETSR--TDLNEWQKPFAHEAKPt----------kDLLEVVRTFkpTILIGVStIGGAFTEEVVREMAk 389
WP_012225053 324 ARITMMDVKGLVEPSR--TDLSEEQRRYAHAAEPt----------rDLMATIRRVrpSVLIGVStVGGAFTQPVVELMAa 391
WP_013581457 319 ERISLFDVNGLLEPSR--KDLSPDQLPYAHPAQPt----------kDLVAAINELkpTILIGVStVGGTFTQQVIEAMSk 386
YP_169914    436 nnNYPIIMPLSNPTSlcEALPEDIIKWTNGkALIAAGspfpdvtyngRDYRISQGNNAFIFPGLGLGSVAVHARVLTKGM 515
AKV00873     409 lnERPIIFPLSNPTDraECTPEQAYRWTKGkALVACGvqfpdvvldgKVYRPGQANNFYVFPAIGLAVYATRPRHIDDRM 488
WP_014403325 389 inQQPIIFPLSNPTEraECTPEAAYTHSGGrALYAAGvqfpdvelhgKRFHPSQANNFYIFPAVSLAVYATRPQRITDAM 468
APR76012     396 lnERPIIFALSNPTDraECSAEQAYTWSKGkALYAAGvqfpdvtvngKTFHPGQANNFYVFPAIGLATYVARPKRITDAC 475
WP_081434091 403 lnERPVIFALSNPTTkaECTAEQAYTWSKGkALFAAGvqfddvefegKIYRPGQANNFYIYPAIGLATYVARPKRLTDEC 482
WP_012812311 392 lnERPIIFPLSLPQKngECTAEQAYEWSKGrALFAAGlqypevtyndRTFYPGQANNFYIFPALGLAVYATCPKLITDEM 471
WP_050726768 388 lnHRPIIFALSNPTDhaECTPREAYGWTNGrAIYAAGvqfpplhldgKTLVPSQANNVYIFPAMGMAIYATQAKRVTDEM 467
WP_025439986 390 lnERPVIFPLSNPTNkaECTAEQAYTWTKGkALYAAGvqfpdfeyqgKSYHPGQANNFYIFPAIGLAVYATRPARITDDM 469
WP_012225053 392 inARPIIFPLSIPh--sECSAEQAYAWSDGrALYAAGvqfpqvmrddHVFRPGQANNFYIFPGLGLAVYATRPRLIPDAL 469
WP_013581457 387 lnERPVIFALSNPTEhaECTAEDAYKFSKGkAIYAAGvqfdpvtidgKTYEPSQANNFYIFPAVGMAIVATEAEHVPDEI 466
YP_169914    516 IRAASYRLSELSPMVinEDITQPLLARITDLVdVTKEITKAVAKQAILEGVHGVdidledltetELDEEIERLINLSS 593
AKV00873     489 FIAAAHATADQVDAE--ERARGMLFPKQASILaTEITTAARVAEHIFDRGEATV----------PRPKDVRAWIEAMT 554
WP_014403325 469 FIAAAAATADQVDQA--SRDKGMLYPLQANILeTEVTTAVRVAEFIFEQGQASV----------ERPVDIRAWIEGML 534
APR76012     476 FVTAAQALADQVGPE--LRARGMLFPSQADILeSEITTAARVAERMFDDGLAQV----------QRPPDIRAWIEGQL 541
WP_081434091 483 FIVAAHATADQVGPA--LCAKGMLYPSQDQILeTEVTTATRIVEYMFDAGLAQV----------ERPRDIRAWIEGQL 548
WP_012812311 472 VIEAAQALADQVDPA--ARERGRLFPPQSDILeVSITSATRIAEFIFDKNAATV----------ERPKDIRAWIENLT 537
WP_050726768 468 FVAAAKAVADQVTQH--QLDDGMLFPPQSNLLeVELDTASKVAESIFEKGLARV----------ERPDDVGSFIRSHA 533
WP_025439986 470 FITAAAATADQVGPS--AREHGMLFPLQANILeTEVTTATRVAEHIFDSGQATV----------ERPENIRAWIEGLL 535
WP_012225053 470 IIEAAHALADQVDVT--AQARGMLYPPQNQILeVQVTSACRLAEYLFDAGLATV----------PRPDDIRSWIEGMT 535
WP_013581457 467 FIAAAKATADQVTDE--QLAKGILFPEQADVQkVSHVTAVKSAEKIFELGLARI----------DKPESVDTLVTSLE 532
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