Conserved Protein Domain Family
MdlB

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COG1132: MdlB 
ABC-type multidrug transport system, ATPase and permease component [Defense mechanisms]
Statistics
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PSSM-Id: 440747
Aligned: 846 rows
Threshold Bit Score: 278.587
Created: 9-Feb-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
WP_081442788   2 MenkthtktnqekneknmsapqtkelgekapgrgrvkvrkG-TLS-RL-LKYVFAY-NWQIIMVIVCIIISAAANAAMGL 77 
WP_012209142   1 Mkke----------------------------------nnR-SLR-KL-LKYSKKY-LKYQKTPLILTPLLLLVSILSPF 42 
WP_006487248   1 Men------------------------------------eKkTVR-RFvFKLFKVYwK-RELLAAVLVGVMIALAVVFPL 42 
WP_041953740   1 -----------------------------------------------M-KKIWKNN-LNILLPLFVVMFIYISLEIGVAM 31 
WP_013658837   1 -----------------------------------------------M-KKIILKY-KLLFSIVFMLKILIGIIFVSVSI 31 
WP_012544349   1 -----------------------------------------------M-KKYFFKN-KLLLTGNIILTLAESILSVMLAF 31 
WP_012514045   1 Me--------------------------------------Q--IK-WL-LSNLKPY-WAFVSLVIFGSILEGLGTSFMTY 37 
WP_011943915   1 Mnlfl--------------------------------ftgH--LRdDI-RKFERKY-KKHYPIFFLLEGLFLTTNVLTPL 44 
WP_011026738   1 -----------------------------------------------M-REFLFKY-KKEFVLAVFFLVASVLINIYFAF 31 
WP_014269654   1 Mk-------------------------------------aS-LVKnSI-INVCKAK-KGTCLVLVIAIFGTVFASLVPPQ 40 
WP_081442788  78 FLQKLIDSYI-LPligkdhPNF-MPLVQGLSVMAAIFLVGAFCTLFYNRILV-KVEQGVLKTIRDDMFTHQQTLPIKYFD 154
WP_012209142  43 LIKYLIDDII-GN------HEF-SQILPFVILFTIVILSERLISFIVNYGYY-KSTNLAARDEQIYMFKKILTIPIKEFS 113
WP_006487248  43 LIRLLIDVVIpS-------GDM-DLLVKYVLLVVGLWFGSLIFTYFGEVVFE-TTALMAKSDLRKQLLEKMFVLPFDFFH 113
WP_041953740  32 FFGYVIDSAS-GA-------IN-MQFSKVMIYTFALLITESVFKWIYEVMSY-KFVAKMSLDTKIYIFNNLIKQDIESFY 101
WP_013658837  32 CLQRIVDAAV-SG-------NS-QQFYRTILWAIGYFVIVGLMDYLNRTIEA-YYMTKTLCHFKKKIFKGLFRQDYTSFY 101
WP_012544349  32 ILANFVDAAV-EY-------DM-ALLYKTCIIFSLYLISVLIVWYSLRIVRA-SYIRQMLFDLKNDIFSKVINKEIDQFQ 101
WP_012514045  38 LVKRIMDDVF-Il------kES-NKLYMILYLFAAAAVVIQIGFFLRNFLMN-MVSEKLLMDFREKMFSSLLYSKVDFFI 108
WP_011943915  45 LIKKTIDSAF-YR------GDV-GEIALFSVLYFIVLVAQSFIMYKLNYSAAkYLLNASRARESKSAYAKILALPLTYAN 116
WP_011026738  32 IYKKLIDVAT-TR-------DL-VKFYSVVKFAVMFTILEAVVGWLNRTTRF-HYMKKTLIYLKDRLFRAIIKKDVEHFN 101
WP_014269654  41 VLKLVIDKNL-VP------K-VpQGLLALALLYLGALLCIGLFDFTKEAVIT-VLGQTITKEIRSEMMDKLETIPASYFS 111
WP_081442788 155 THLHGDVMSFYTNDTDALRQAISQSLPQMFSSIMSVAAAFVAMLIISVPLTAFVVLFALLLLVVIRQLAVASGKFFVKQQ 234
WP_012209142 114 YNKIGDFMSRVLSDTLEVSFFLGAGISVITYNIIQLIVVSLVLLYLNWQLAVITFIMVPFYYFSLRAFDKNLQKSSELER 193
WP_006487248 114 KNKTGELVSRLISDLELVGTVIAQVFPILLLGVVQITAILAIMFAFNWKLTLLPLGFIVFSFLVIMFFNIMVEKRSKVER 193
WP_041953740 102 NNDVGDKISILTNDINTIETEYFRTFLNLVKSGFLFLFAFGTIFYVSYQMTIALMILSIISFVFGNIPMKNLKTFKEKFS 181
WP_013658837 102 KENTSVYLSSLTNDIHLMDKNYINPALGIVMDLVIIVGSTGVLIWFNIWIALAMILTSTIILFIPKVFGNRLASTRARYS 181
WP_012544349 102 KGNSASYISTLNNDITILEQDYFKNILTMVALIFSFIIATVAIFKLNFFIAVGVFVISIFLVAIPYLFREKISRAKKEFS 181
WP_012514045 109 NHPSGDIISRFNNDINAIKNILIDYMLSLIKEPITVLLLLGVLIYRDIYLTIIIIFAFPIISYSVKYFGTKRAKYVKLNQ 188
WP_011943915 117 SQNTGDYLSVFMRDVPKVASGVYLGRLQFFFNLGFFLAVLFLLFILSVKLTLVVLVSIVLFFVSTSILRKMVIRASQRDQ 196
WP_011026738 102 EVNTGKYISIISNDVKIVEEDYFNNFFRLLGSAVGFVAALISLFILSYKITVMIILMAILSVIIPRIFDDKIAKMRNDYS 181
WP_014269654 112 SQNAGEIVSRFTNDVDSINAMFSSGIVGLAIDCFKIIGIVISIWLFSSQLGLIVLVLLPVIFLISRLFQKSMLKAQLENR 191
WP_081442788 235 QELGDVNGFIEEAINGQKVIKVFTHEEATQKTFDQKNSTLYDASSQANYFGNITMPVVGNMGYLLYVLVAIVGAGAALSn 314
WP_012209142 194 IAYSDLTEELREKIEGLMPIKSFCKENFFSKQFSYISWIWVKKKNRLNMLNQSAEDFMSFIYELIPVLILGYGAYLILK- 272
WP_006487248 194 EKFGELAGVTSNIIDNMKLIRIAMPFAWVMNFFDRFQGDHIYAGKRFIKSIKIAGTLKTSINGLISFSLLAYGGYLVMK- 272
WP_041953740 182 NSQSEYTARTSEYFNGYETIKVFGLEKFISKVFYNNSKNVYDKGLAYQKRYSLVTMISYFFGGFTFLGGFVCGGYLAYK- 260
WP_013658837 182 EGLSELTKKLKDMFLGYEVVKSYHMDDQIIEEFQECNKEVEKRNYTAIEATSRTNALASYLSIMTQLVAIGLGGYFVIK- 260
WP_012544349 182 DSLSDLTVQTNDILSGFEVVKSFNVEKLVEGQYKKYNKKVEDNRFFFEKMLALANSLTEFFGYLMFFASLGLGAYLVIK- 260
WP_012514045 189 ERLGIINQHVTQLISGIENIKIFGAENKFLERFVQANKNLFKAGIKTIFYTVMNSIFNQSTGYIVFGLVLLYGGYRIVH- 267
WP_011943915 197 ESYQRFLKRSREVVEGIPVLKQFSGSSFLKNFLDSSAGEWSRASIAHSTANELSNRNIDINRWIGSTIVLAFGIYLLWK- 275
WP_011026738 182 ESLELFTIESKDTLTGLEVIKSFGIEDKVHEKFSKVNEDVEDKKLKYSVLLNTSDTMSEILSSFIFLSVFAVGLYFTIK- 260
WP_014269654 192 RVIGRVNNHIGESIKNMLMIKSNSKERYMEETYTKYLQQNFKTIEKVNFFDSVFPPIIQITRALVIALIVVLSSKELHFl 271
WP_081442788 315 fhnfsltGssALTIGGIVSFLTLSRSFINPIGQISNQFSFVLMALAGASRIFDFLDEKPESN-Sgevtlikahvaedgti 393
WP_012209142 273 -------G--NATLGTLMGFYAYLGWIFTPIRNLSSFYIQMQRVRQVSERIFEIHDFPEENM-R---------------- 326
WP_006487248 273 -------G--EITVGILMTFWAYVQSLFNPIQLLMQVNILLRQSWGGLLRTIEVLEAPEEER-S---------------- 326
WP_041953740 261 -------G--FITLGQMIVCVQLTNHIVNPLMFAIESYGKFKSVDKILNKIENTLISEENV--E---------------- 313
WP_013658837 261 -------G--NLTIGTLFAIVQLGVNLGEPITMIIEKITMIKSMQIVKDRLLAFIDIEDVD--E---------------- 313
WP_012544349 261 -------R--ILEPGLMIAAVQLMNNIVNPMIGIIERVNALKGTESIQKKIMDIMEDKEQQ--E---------------- 313
WP_012514045 268 -------G--YTSAGNFISYITALLLIQMPIMETQKGFMNMRSSIPLVKRVQEMLLLQKEK--D---------------- 320
WP_011943915 276 -------G--EISVGTLLAFESYMNWMYDIVRMALTGLTMFFSTLPNWENFARIFSMPf----E---------------- 326
WP_011026738 261 -------G--EMTLGTMIACVQLTNNIIMPIYSMGQNLNRILSLKSISQKINEVLQEKEER--N---------------- 313
WP_014269654 272 -------G---ITLGMVAASIDLVSNLFIPIENLGMELQNIQSSIAGSRRVDEFYREKEDDSkDtt-------------- 327
WP_081442788 394 tqaahhtdkwawrvpagvrvnkdvAnvtvaankssridearassiaalaggssrKEAsA-Y-TLLRGDIRFNDVRFSY-E 470
WP_012209142 327 -------------------------------------------------------EGkS-F-PNNDYPITYENVCFKY-K 348
WP_006487248 327 -------------------------------------------------------NSsPkL--EDVRSISLENIAFGY-G 348
WP_041953740 314 --------------------------------------------------------TtE-I-KDFNNKISLEDVSFKY-- 333
WP_013658837 314 ------------------------------------------------------NRFiE-L-KEFKSSIQVEDVTFGY-E 336
WP_012544349 314 ------------------------------------------------------GEFiS-K-TDFNDAIVFENVSFSYgR 337
WP_012514045 321 -------------------------------------------------------GTiN-I-GNLLVPIVMKNVYVTI-D 342
WP_011943915 327 ------------------------R-----------------------------ASGiN-L-EKFE-KLQLRNVYFKY-D 349
WP_011026738 314 -------------------------------------------------------DYiP-V-KSFNDSIEFKNVSFSY-T 335
WP_014269654 328 -----------------------iT-----------------------------AKAi--LsQKTTANLVFDHVSFHY-D 352
WP_081442788 471 PGHEVLHDISLYAKPGQKVALVGATGAGKTTITNLINRFYDIDSGSILYDGINIKDINKRDLR-QSLGIVLQDVNLFTG- 548
WP_012209142 349 -DSTVLHDINLTIGTKEKVAIVGTSGAGKSSFVNLIPRFYEPATGKVMINGIDVKKYNLKQLR-KNITIVRQDDYLFNM- 425
WP_006487248 349 -NKQILKGLSLELRKGEITTLVGESGAGKTTTLNILMGLQKPQSGTIYINGDPVSNSAL--LR-PYIGFVEQTPTLFEKc 424
WP_041953740 334 DDKKVLENISFDFEKGKKYALVGLSGSGKSTLMKLISKRIKADEGKICIDGTDLDEISRNSII-NLISTINQNVFLFKG- 411
WP_013658837 337 EGYDILKSVSLQFEKNKKYAIVGASGSGKSTLLKLLLDEYIPRSGHITIDGQQLQEVLKSSLY-QQLAIIHQNVYLFDK- 414
WP_012544349 338 REEPTLKNISFTVKKGEKCAIIGPSGSGKSTIVKLLLKYYNNFEGRILIDGIDIRNIKTEDLYnNLISVIHQNVFMFDT- 416
WP_012514045 343 -SKEILKDINLTINPGEKIGIVGPTGAGKSTLLDILPKLV-SYKGDVYIKDKSLEDITNKSIR-SKIAFASQHVFIFND- 418
WP_011943915 350 -GTPVLTGLNFEINSGDKIAIVARSGAGKSTLVSLFNRLLSPTEGEILINGVPIEQYSLQSLR-RNIVLVRSNDILFDT- 426
WP_011026738 336 GETKALDNINFTIKKGGKYALVGTSGAGKSTILKLLLKQYENYEGEIKLDGIELRRIDKKDLF-KIITLLHQNVFIFDG- 413
WP_014269654 353 KGVEILKDISLNIQDREKVTLVGRTGVGKSTLFKLVLGLLKPTKGSITINGVDVYAIPNSEKR-KLFGYVDQGFQIIVG- 430
WP_081442788 549 TVIDNIRYGKLDATDDECISAAKLANADSFIRMLPHGYNTVLQGDGSGLSQGQRQLISIARAAVADPPVMILDEATSSID 628
WP_012209142 426 TVKENIML-DDEFTQEEFMKAVKKAKVDKFIGLLDEGYDTVVGERGSKLSDGQRQRVAIARALIREPKVLILDEATSGVD 504
WP_006487248 425 TLLENITLGR-SISKASLENIFERTNLDVLLRRFENGLDTLVAD--IQLSGGERQLVALARALVSNPRLLILDEITANID 501
WP_041953740 412 SIYDNITLFSKDYSEEKVKDVILKAELGKYLDRLYDKEL--ISENANNLSGGEKQRISIARSLIKDTKIILADEILSSLD 489
WP_013658837 415 SLKENITLGKC-FQESEIEEAMQKSAINEFLNKRTYGEDETLGEDGNKLSGGQRQRVAIARALIQRKPILLLDEYTSSLD 493
WP_012544349 417 SIKNNITLFKE-YDEKVIERAISLSGLKEFIEKLPDKENTEVGEKGSNLSGGERQRISIARALIKGTPILVSDEPTSSLD 495
WP_012514045 419 TVRNNLLIANPNASEELLIKAIKLAK-AEFLFTLKNGLDTVLGEYGYTVSGGERQRIAIARIFLTNPDIILLDEITSALD 497
WP_011943915 427 TIRNNITLFE-DFPEDEIENVLKMCEc-DFVEKLESGIDTIVGERGTKLSDGQRQRIVLARALIRKPQVLILDEATSGVD 504
WP_011026738 414 TVKDNITLFNDRYTDEEVVRAAKIAGLGPLLEKLPEGILSDVGEGGKLLSGGERQRIAIARSIITNASILALDEATAALD 493
WP_014269654 431 TIGEQISLKDPSITKEQIERALEVVDLTEYVHSLEKGIDTPVSDNSL-FSQGQKQLLAIARAIVTDPPILLLDEITANLD 509
WP_081442788 629 TRTEQIVQAGMDALME-GRTVFVIAHRL--STVRNSDVIMVMDHGRIIERGTHDQLLEEKGEYYQLYTGAF-E-L 698
WP_012209142 505 SQTEEEIFDELKE--Y-EMTLIIISHRL--STIRKADKVILLKDGEIRGEGMHEELLKNAPIYKEIIESQL-V-V 572
WP_006487248 502 SKTEEIIQNTLLGLRSeGIIVLMVAHRL--STVLLSDRVALISNGVIVASGTHNELLKTSSEYKKLYSLQLiKde 574
WP_041953740 490 NEIAFSIEKGLLE-LE-NITLISVTHRLikENLKQYDKILVLKDGKIEEKGNFEELMNFDSYFKKLYTISE-V-E 560
WP_013658837 494 SKVAYAIEDTILN-LQ-DVTVVSVTHKLmdSLLKRYDRIIVMEDGRVVEQGGFQELLEKRQVFYKLYHAEH-Q-M 564
WP_012544349 496 KKTALSIENSILS-IE-GLTALVITHNTseEVLKKYDKIIFVEDGEVVKVGTFDEIFTPASVVLSVVG------- 561
WP_012514045 498 VHTEQAVISNIFEVFK-DKTILIVAHRL--SNIINCDRILYIEDGRILEEGTFEELMRKQGNFYTLYQKS--R-- 565
WP_011943915 505 GKTEERIFEKI--LREi-ETVIIISHRL--STVRKAKKIYVMENGRILDSGSHEELIVRCEKYTEILKEQF-V-E 572
WP_011026738 494 NETAYMIEKTILD-MD--ITAIVVTHRLwsELLKRYDEIIVLRDGRIVEKGRFDDLMKMKGYFYSLFNIEK-L-D 563
WP_014269654 510 SVTEAKLTAVLQKTSQ-EHTVLSISHRL--SSLVDCDTMVILEKGKVKNSGSPQKLMEEDDWFRSHRELE--KlT 579
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