| - GRCh37:
- Chr10:86194737-90910559
- GRCh38:
- Chr10:84434981-89150802
| ATAD1, ACTA2, ACTA2-AS1, ADIRF, ADIRF-AS1, AGAP11, ANKRD22, BMPR1A, CCSER2, FAM245A, FAM25A, FAS, FAS-AS1, GLUD1, GRID1, GRID1-AS1, KLLN, LDB3, LINC00863, LINC01519, LINC01520, LINC02647, LIPF, LIPJ, LIPK, LIPM, LIPN, LOC101929662, LOC110121486, LOC111982877, LOC111982878, LOC116216117, LOC121366069, LOC121366070, LOC121366071, LOC121815954, LOC124416859, LOC124416860, LOC124416861, LOC124416862, LOC124416863, LOC124416864, LOC126860987, LOC126860988, LOC126860989, LOC126860990, LOC126860991, LOC126860992, LOC126860993, LOC129390211, LOC129390212, LOC129390213, LOC130004223, LOC130004224, LOC130004225, LOC130004226, LOC130004227, LOC130004228, LOC130004229, LOC130004230, LOC130004231, LOC130004232, LOC130004233, LOC130004234, LOC130004235, LOC130004236, LOC130004237, LOC130004238, LOC130004239, LOC130004240, LOC130004241, LOC130004242, LOC130004243, LOC130004244, LOC130004245, LOC130004246, LOC130004247, LOC130004248, LOC130004249, LOC130004250, LOC130004251, LOC130004252, LOC130004253, LOC130004254, LOC130004255, LOC130004256, LOC130004257, LOC130004258, LOC130004259, LOC130004260, LOC130004261, LOC130004262, LOC130004263, LOC130004264, LOC130004265, LOC130004266, LOC130004267, LOC130004268, LOC130004269, LOC130004270, LOC130004271, LOC130004272, LOC130004273, LOC130004274, LOC130004275, LOC130004276, LOC130004277, LOC130004278, LOC130004279, LOC130004280, LOC130004281, LOC130004282, LOC130004283, LOC130004284, LOC130004285, LOC130004286, LOC130004287, LOC130004288, LOC130004289, LOC130004290, LOC130004291, LOC130004292, LOC130004293, LOC130004294, LOC130004295, LOC130004296, LOC132089869, LOC132089870, LOC132089871, LOC132089872, LOC132089873, LOC132089874, LOC132089875, LOC132089876, LOC132090824, MINPP1, MIR346, MIR4678, MIR4679-1, MIR4679-2, MMRN2, NUTM2A, NUTM2A-AS1, NUTM2D, OPN4, PAPSS2, PTEN, RNLS, SHLD2, SNCG, STAMBPL1, WAPL, WAPL-DT | | See cases | Pathogenic
(Aug 12, 2011) | criteria provided, single submitter |
| - GRCh37:
- Chr10:88514773-89725239
- GRCh38:
- Chr10:86755016-87965482
| LOC111982877, LOC111982878, LOC116216117, LOC121366070, LOC130004250, LOC130004251, LOC124416863, LOC126860989, LOC126860990, LOC121366071, LOC124416862, LOC126860991, LOC129390212, LOC130004248, LOC130004249, LOC129390213, LOC130004245, LOC130004246, LOC130004247, ADIRF, ADIRF-AS1, AGAP11, ATAD1, BMPR1A, FAM245A, FAM25A, GLUD1, KLLN, LINC00863, LOC130004252, LOC130004253, LOC130004254, LOC130004255, LOC130004256, LOC130004257, LOC130004258, LOC130004259, LOC130004260, LOC130004261, LOC130004262, LOC130004263, LOC130004264, LOC130004265, LOC130004266, LOC130004267, LOC130004268, LOC130004269, LOC130004270, LOC130004271, LOC130004272, LOC130004273, LOC130004274, LOC130004275, MINPP1, MIR4678, MMRN2, NUTM2A, NUTM2A-AS1, NUTM2D, PAPSS2, PTEN, SHLD2, SNCG | | Generalized juvenile polyposis/juvenile polyposis coli | Pathogenic
(Mar 6, 2019) | criteria provided, single submitter |
| - GRCh37:
- Chr10:88598623-89725239
- GRCh38:
- Chr10:86838866-87965482
| ADIRF, ADIRF-AS1, AGAP11, ATAD1, BMPR1A, FAM245A, FAM25A, GLUD1, KLLN, LINC00863, LOC111982877, LOC111982878, LOC116216117, LOC121366070, LOC121366071, LOC124416862, LOC124416863, LOC126860989, LOC126860990, LOC126860991, LOC129390212, LOC129390213, LOC130004246, LOC130004247, LOC130004248, LOC130004249, LOC130004250, LOC130004251, LOC130004252, LOC130004253, LOC130004254, LOC130004255, LOC130004256, LOC130004257, LOC130004258, LOC130004259, LOC130004260, LOC130004261, LOC130004262, LOC130004263, LOC130004264, LOC130004265, LOC130004266, LOC130004267, LOC130004268, LOC130004269, LOC130004270, LOC130004271, LOC130004272, LOC130004273, LOC130004274, LOC130004275, MINPP1, MIR4678, MMRN2, NUTM2A, NUTM2A-AS1, NUTM2D, PAPSS2, PTEN, SHLD2, SNCG | | Generalized juvenile polyposis/juvenile polyposis coli | Pathogenic
(Nov 1, 2018) | criteria provided, single submitter |
| - GRCh37:
- Chr10:88635625-89653886
- GRCh38:
- Chr10:86875868-87894129
| LOC130004268, LOC130004269, LOC130004270, LOC130004271, LOC130004272, LOC130004273, LOC130004274, MINPP1, LOC111982877, LOC111982878, LOC116216117, LOC121366071, LOC124416862, LOC121366070, MIR4678, MMRN2, NUTM2A, NUTM2A-AS1, NUTM2D, PAPSS2, LOC124416863, LOC126860989, ATAD1, ADIRF, ADIRF-AS1, AGAP11, BMPR1A, FAM245A, FAM25A, GLUD1, KLLN, LINC00863, LOC126860990, LOC126860991, LOC129390212, LOC129390213, LOC130004248, LOC130004249, LOC130004250, LOC130004251, LOC130004252, LOC130004253, LOC130004254, LOC130004255, LOC130004256, LOC130004257, LOC130004258, LOC130004259, LOC130004260, LOC130004261, LOC130004262, LOC130004263, LOC130004264, LOC130004265, LOC130004266, LOC130004267, PTEN, SHLD2, SNCG | | PTEN hamartoma tumor syndrome | Pathogenic
(Sep 17, 2018) | criteria provided, single submitter |
| - GRCh37:
- Chr10:89590587-90376982
- GRCh38:
- Chr10:87830830-88617225
| LOC130004269, LOC130004270, LOC130004271, LOC130004272, LOC130004273, KLLN, LOC124416863, LOC124416864, LOC126860991, LIPJ, LOC121815954, ATAD1, LOC130004274, LOC130004275, LOC130004276, LOC130004277, LOC130004278, LOC130004279, LOC130004280, LOC130004281, LOC130004282, LOC130004283, LOC130004284, PTEN, RNLS | | Poly (ADP-Ribose) polymerase inhibitor response | drug response
(Nov 27, 2017) | no assertion criteria provided |
| - GRCh37:
- Chr10:89621727
- GRCh38:
- Chr10:87861970
| KLLN, PTEN | K173R | not specified | Uncertain significance
(Jul 23, 2019) | criteria provided, single submitter |
| - GRCh37:
- Chr10:89621800
- GRCh38:
- Chr10:87862043
| KLLN, PTEN | W149R | not specified, not provided | Benign
(Nov 1, 2022) | criteria provided, multiple submitters, no conflicts |
| - GRCh37:
- Chr10:89621853
- GRCh38:
- Chr10:87862096
| KLLN, PTEN | N131S | not specified, not provided | Benign
(Nov 1, 2022) | criteria provided, multiple submitters, no conflicts |
| - GRCh37:
- Chr10:89621861
- GRCh38:
- Chr10:87862104
| KLLN, PTEN | | not specified | Uncertain significance
(Mar 3, 2020) | criteria provided, single submitter |
| - GRCh37:
- Chr10:89621863
- GRCh38:
- Chr10:87862106
| KLLN, PTEN | R128G | not provided, not specified | Benign
(Nov 1, 2022) | criteria provided, multiple submitters, no conflicts |
| - GRCh37:
- Chr10:89621902-89621903
- GRCh38:
- Chr10:87862145-87862146
| KLLN, PTEN | A115fs | not specified | Uncertain significance
(Apr 20, 2020) | criteria provided, single submitter |
| - GRCh37:
- Chr10:89621905-89621906
- GRCh38:
- Chr10:87862148-87862149
| KLLN, PTEN | A115fs | not specified, not provided | Conflicting interpretations of pathogenicity
(Aug 15, 2023) | criteria provided, conflicting interpretations |
| - GRCh37:
- Chr10:89622010
- GRCh38:
- Chr10:87862253
| KLLN, PTEN | P79T | not specified | Uncertain significance
(Apr 20, 2020) | criteria provided, single submitter |
| - GRCh37:
- Chr10:89622011
- GRCh38:
- Chr10:87862254
| KLLN, PTEN | | not specified | Uncertain significance
(Apr 20, 2020) | criteria provided, single submitter |
| - GRCh37:
- Chr10:89622041
- GRCh38:
- Chr10:87862284
| KLLN, LOC130004271, PTEN | | not specified | Uncertain significance
(Nov 30, 2021) | criteria provided, single submitter |
| - GRCh37:
- Chr10:89622114
- GRCh38:
- Chr10:87862357
| KLLN, PTEN | G44A | not specified | Uncertain significance
(Dec 18, 2020) | criteria provided, single submitter |
| - GRCh37:
- Chr10:89622115
- GRCh38:
- Chr10:87862358
| KLLN, PTEN | G44R | not specified | Uncertain significance
(Dec 18, 2020) | criteria provided, single submitter |
| - GRCh37:
- Chr10:89622179
- GRCh38:
- Chr10:87862422
| KLLN, PTEN | | not specified | Uncertain significance
(Nov 15, 2019) | criteria provided, single submitter |
| - GRCh37:
- Chr10:89622180
- GRCh38:
- Chr10:87862423
| KLLN, PTEN | V22D | Inborn genetic diseases, not specified | Uncertain significance
(Feb 22, 2023) | criteria provided, multiple submitters, no conflicts |
| - GRCh37:
- Chr10:89622187
- GRCh38:
- Chr10:87862430
| KLLN, PTEN | Y20H | not specified | Likely benign
(Apr 2, 2019) | criteria provided, single submitter |
| - GRCh37:
- Chr10:89622188
- GRCh38:
- Chr10:87862431
| KLLN, PTEN | | not specified | Likely benign
(Apr 2, 2019) | criteria provided, single submitter |
| - GRCh37:
- Chr10:89622228
- GRCh38:
- Chr10:87862471
| KLLN, PTEN | P6L | not specified | Uncertain significance
(Jan 4, 2021) | criteria provided, single submitter |
| - GRCh37:
- Chr10:89622885
- GRCh38:
- Chr10:87863128
| KLLN, PTEN | | not provided | Uncertain significance
(Jul 9, 2014) | criteria provided, single submitter |
| - GRCh37:
- Chr10:89622888
- GRCh38:
- Chr10:87863131
| KLLN, PTEN | | not provided | Uncertain significance
(Aug 30, 2019) | criteria provided, multiple submitters, no conflicts |
| - GRCh37:
- Chr10:89622891
- GRCh38:
- Chr10:87863134
| KLLN, PTEN | | not provided | Uncertain significance
(Dec 1, 2015) | criteria provided, single submitter |
| - GRCh37:
- Chr10:89622896
- GRCh38:
- Chr10:87863139
| KLLN, PTEN | | not specified | Uncertain significance
(Mar 30, 2015) | criteria provided, single submitter |
| - GRCh37:
- Chr10:89622902
- GRCh38:
- Chr10:87863145
| KLLN, PTEN | | not provided | Uncertain significance
(Dec 31, 2014) | criteria provided, single submitter |
| - GRCh37:
- Chr10:89622905
- GRCh38:
- Chr10:87863148
| KLLN, PTEN | | not provided | Uncertain significance
(Jun 21, 2017) | criteria provided, single submitter |
| - GRCh37:
- Chr10:89622915
- GRCh38:
- Chr10:87863158
| KLLN, PTEN | | PTEN hamartoma tumor syndrome | Benign
(Jun 2, 2017) | reviewed by expert panel
FDA Recognized Database |
| - GRCh37:
- Chr10:89622916
- GRCh38:
- Chr10:87863159
| KLLN, PTEN | | not provided | Uncertain significance
(May 12, 2015) | criteria provided, single submitter |
| - GRCh37:
- Chr10:89622918-89624325
- GRCh38:
- Chr10:87863161-87864568
| KLLN, LOC130004273, LOC130004274, PTEN | | PTEN hamartoma tumor syndrome | Uncertain significance
(Feb 27, 2018) | criteria provided, single submitter |
| - GRCh37:
- Chr10:89622919
- GRCh38:
- Chr10:87863162
| KLLN, PTEN | | not provided | Uncertain significance
(Aug 16, 2016) | criteria provided, single submitter |
| - GRCh37:
- Chr10:89622921
- GRCh38:
- Chr10:87863164
| KLLN, PTEN | | not specified | Uncertain significance
(Apr 28, 2017) | criteria provided, single submitter |
| - GRCh37:
- Chr10:89622925
- GRCh38:
- Chr10:87863168
| KLLN, PTEN | | not provided | Uncertain significance
(Mar 26, 2016) | criteria provided, single submitter |
| - GRCh37:
- Chr10:89622928-89624315
- GRCh38:
- Chr10:87863171-87864558
| KLLN, LOC130004273, LOC130004274, PTEN | | PTEN hamartoma tumor syndrome | Pathogenic
(Sep 9, 2021) | criteria provided, single submitter |
| - GRCh37:
- Chr10:89622928
- GRCh38:
- Chr10:87863171
| KLLN, PTEN | | not provided | Uncertain significance
(Oct 11, 2017) | criteria provided, single submitter |
| - GRCh37:
- Chr10:89622931
- GRCh38:
- Chr10:87863174
| KLLN, PTEN | | not provided | Uncertain significance
(Oct 9, 2017) | criteria provided, single submitter |
| - GRCh37:
- Chr10:89622933
- GRCh38:
- Chr10:87863176
| KLLN, PTEN | | not provided | Uncertain significance
(Sep 26, 2016) | criteria provided, single submitter |
| - GRCh37:
- Chr10:89622936
- GRCh38:
- Chr10:87863179
| KLLN, PTEN | | not specified | Uncertain significance
(Oct 13, 2016) | criteria provided, single submitter |
| - GRCh37:
- Chr10:89622938-89622939
- GRCh38:
- Chr10:87863181-87863182
| KLLN, PTEN | | Hereditary cancer-predisposing syndrome, not provided | Uncertain significance
(Feb 22, 2019) | criteria provided, multiple submitters, no conflicts |
| - GRCh37:
- Chr10:89622939
- GRCh38:
- Chr10:87863182
| KLLN, PTEN | | Hereditary cancer-predisposing syndrome, not provided | Uncertain significance
(Mar 17, 2018) | criteria provided, multiple submitters, no conflicts |
| - GRCh37:
- Chr10:89622939
- GRCh38:
- Chr10:87863182
| KLLN, PTEN | | Hereditary cancer-predisposing syndrome | Uncertain significance
(Sep 7, 2017) | criteria provided, single submitter |
| - GRCh37:
- Chr10:89622940
- GRCh38:
- Chr10:87863183
| KLLN, PTEN | | Hereditary cancer-predisposing syndrome | Uncertain significance
(Jul 20, 2017) | criteria provided, single submitter |
| - GRCh37:
- Chr10:89622941
- GRCh38:
- Chr10:87863184
| KLLN, PTEN | | Hereditary cancer-predisposing syndrome | Uncertain significance
(May 9, 2018) | criteria provided, single submitter |
| - GRCh37:
- Chr10:89622942
- GRCh38:
- Chr10:87863185
| KLLN, PTEN | | Hereditary cancer-predisposing syndrome | Uncertain significance
(Jun 7, 2018) | criteria provided, single submitter |
| - GRCh37:
- Chr10:89622944-89622945
- GRCh38:
- Chr10:87863187-87863188
| KLLN, PTEN | | Hereditary cancer-predisposing syndrome | Uncertain significance
(Nov 1, 2018) | criteria provided, single submitter |
| - GRCh37:
- Chr10:89622945
- GRCh38:
- Chr10:87863188
| KLLN, PTEN | | not provided | Uncertain significance
(May 2, 2016) | criteria provided, single submitter |
| - GRCh37:
- Chr10:89622947
- GRCh38:
- Chr10:87863190
| KLLN, PTEN | | Hereditary cancer-predisposing syndrome | Uncertain significance
(Apr 7, 2016) | criteria provided, single submitter |
| - GRCh37:
- Chr10:89622951
- GRCh38:
- Chr10:87863194
| KLLN, PTEN | | not provided, Hereditary cancer-predisposing syndrome | Uncertain significance
(May 2, 2018) | criteria provided, multiple submitters, no conflicts |
| - GRCh37:
- Chr10:89622960
- GRCh38:
- Chr10:87863203
| KLLN, PTEN | | not provided | Uncertain significance
(Jan 26, 2015) | criteria provided, single submitter |
| - GRCh37:
- Chr10:89622964
- GRCh38:
- Chr10:87863207
| KLLN, PTEN | | not specified | Uncertain significance | no assertion criteria provided |
| - GRCh37:
- Chr10:89622965
- GRCh38:
- Chr10:87863208
| KLLN, PTEN | | Hereditary cancer-predisposing syndrome | Uncertain significance
(Oct 16, 2019) | criteria provided, single submitter |
| - GRCh37:
- Chr10:89622970
- GRCh38:
- Chr10:87863213
| KLLN, PTEN | | Hereditary cancer-predisposing syndrome | Uncertain significance
(Oct 24, 2019) | criteria provided, single submitter |
| - GRCh37:
- Chr10:89622972-89623860
- GRCh38:
- Chr10:87863215-87864103
| KLLN, LOC130004273, LOC130004274, PTEN | | Hereditary cancer-predisposing syndrome | Uncertain significance
(Jul 28, 2021) | criteria provided, single submitter |
| - GRCh37:
- Chr10:89622976-89622977
- GRCh38:
- Chr10:87863219-87863220
| KLLN, PTEN | | Hereditary cancer-predisposing syndrome, not specified | Uncertain significance
(Sep 27, 2018) | criteria provided, multiple submitters, no conflicts |
| - GRCh37:
- Chr10:89622980
- GRCh38:
- Chr10:87863223
| KLLN, PTEN | | VACTERL with hydrocephalus, Cowden syndrome 1, Macrocephaly-autism syndrome,
Glioma susceptibility 2, PTEN hamartoma tumor syndrome, Familial meningioma,
Malignant tumor of prostate, not provided | Uncertain significance
(Oct 31, 2018) | criteria provided, multiple submitters, no conflicts |
| - GRCh37:
- Chr10:89622982
- GRCh38:
- Chr10:87863225
| KLLN, PTEN | | Hereditary cancer-predisposing syndrome | Uncertain significance
(Feb 23, 2018) | criteria provided, single submitter |
| - GRCh37:
- Chr10:89622983
- GRCh38:
- Chr10:87863226
| KLLN, PTEN | | PTEN-related condition, Hereditary cancer-predisposing syndrome | Uncertain significance
(Jul 12, 2023) | criteria provided, multiple submitters, no conflicts |
| - GRCh37:
- Chr10:89622984
- GRCh38:
- Chr10:87863227
| KLLN, PTEN | | not provided, PTEN hamartoma tumor syndrome | Uncertain significance
(May 28, 2019) | criteria provided, multiple submitters, no conflicts |
| - GRCh37:
- Chr10:89622986
- GRCh38:
- Chr10:87863229
| KLLN, PTEN | | not provided | Uncertain significance
(Jul 28, 2015) | criteria provided, single submitter |
| - GRCh37:
- Chr10:89622989
- GRCh38:
- Chr10:87863232
| KLLN, PTEN | | Hereditary cancer-predisposing syndrome | Uncertain significance
(Jan 25, 2019) | criteria provided, single submitter |
| - GRCh37:
- Chr10:89622989
- GRCh38:
- Chr10:87863232
| KLLN, PTEN | | Hereditary cancer-predisposing syndrome | Uncertain significance
(Dec 26, 2017) | criteria provided, single submitter |
| - GRCh37:
- Chr10:89622991
- GRCh38:
- Chr10:87863234
| KLLN, PTEN | | Hereditary cancer-predisposing syndrome | Uncertain significance
(Apr 23, 2018) | criteria provided, single submitter |
| - GRCh37:
- Chr10:89622991
- GRCh38:
- Chr10:87863234
| KLLN, PTEN | | not provided, Hereditary cancer-predisposing syndrome | Uncertain significance
(Feb 25, 2019) | criteria provided, multiple submitters, no conflicts |
| - GRCh37:
- Chr10:89622992
- GRCh38:
- Chr10:87863235
| KLLN, PTEN | | not specified, Cowden syndrome 4 | Uncertain significance
(Dec 9, 2020) | criteria provided, multiple submitters, no conflicts |
| - GRCh37:
- Chr10:89622992
- GRCh38:
- Chr10:87863235
| KLLN, PTEN | | not provided | Uncertain significance
(Jan 3, 2014) | criteria provided, single submitter |
| - GRCh37:
- Chr10:89622995
- GRCh38:
- Chr10:87863238
| KLLN, PTEN | | Hereditary cancer-predisposing syndrome | Uncertain significance
(May 29, 2020) | criteria provided, single submitter |
| - GRCh37:
- Chr10:89623000
- GRCh38:
- Chr10:87863243
| KLLN, PTEN | | not provided | Uncertain significance
(Sep 29, 2016) | criteria provided, single submitter |
| - GRCh37:
- Chr10:89623002
- GRCh38:
- Chr10:87863245
| KLLN, PTEN | | not provided | Uncertain significance
(Oct 17, 2017) | criteria provided, single submitter |
| - GRCh37:
- Chr10:89623004
- GRCh38:
- Chr10:87863247
| KLLN, PTEN | | not provided | Uncertain significance
(Apr 4, 2018) | criteria provided, single submitter |
| - GRCh37:
- Chr10:89623005
- GRCh38:
- Chr10:87863248
| KLLN, PTEN | | not provided | Uncertain significance
(Nov 9, 2016) | criteria provided, single submitter |
| - GRCh37:
- Chr10:89623005
- GRCh38:
- Chr10:87863248
| KLLN, PTEN | | not provided | Uncertain significance
(May 25, 2020) | criteria provided, multiple submitters, no conflicts |
| - GRCh37:
- Chr10:89623010
- GRCh38:
- Chr10:87863253
| KLLN, PTEN | | Hereditary cancer-predisposing syndrome | Uncertain significance
(Oct 30, 2014) | criteria provided, single submitter |
| - GRCh37:
- Chr10:89623012
- GRCh38:
- Chr10:87863255
| KLLN, PTEN | | Hereditary cancer-predisposing syndrome | Uncertain significance
(Apr 2, 2014) | criteria provided, single submitter |
| - GRCh37:
- Chr10:89623014
- GRCh38:
- Chr10:87863257
| KLLN, PTEN | | not provided | Uncertain significance
(Oct 27, 2017) | criteria provided, multiple submitters, no conflicts |
| - GRCh37:
- Chr10:89623015
- GRCh38:
- Chr10:87863258
| KLLN, PTEN | | Hereditary cancer-predisposing syndrome | Uncertain significance
(Oct 9, 2017) | criteria provided, single submitter |
| - GRCh37:
- Chr10:89623016
- GRCh38:
- Chr10:87863259
| KLLN, PTEN | | not provided | Uncertain significance
(Aug 11, 2017) | criteria provided, single submitter |
| - GRCh37:
- Chr10:89623018
- GRCh38:
- Chr10:87863261
| KLLN, PTEN | | not provided | Uncertain significance
(Apr 21, 2014) | criteria provided, single submitter |
| - GRCh37:
- Chr10:89623019
- GRCh38:
- Chr10:87863262
| KLLN, PTEN | | not provided | Uncertain significance
(Apr 8, 2020) | criteria provided, multiple submitters, no conflicts |
| - GRCh37:
- Chr10:89623020
- GRCh38:
- Chr10:87863263
| KLLN, PTEN | | not provided | Uncertain significance
(May 11, 2015) | criteria provided, single submitter |
| - GRCh37:
- Chr10:89623021
- GRCh38:
- Chr10:87863264
| KLLN, PTEN | | not provided, Macrocephaly-autism syndrome, Familial meningioma,
Malignant tumor of prostate, Cowden syndrome 1, Glioma susceptibility 2
| Uncertain significance
(Mar 15, 2022) | criteria provided, multiple submitters, no conflicts |
| - GRCh37:
- Chr10:89623024
- GRCh38:
- Chr10:87863267
| KLLN, PTEN | | not provided | Uncertain significance
(Nov 29, 2017) | criteria provided, single submitter |
| - GRCh37:
- Chr10:89623027-89623038
- GRCh38:
- Chr10:87863270-87863281
| KLLN, PTEN | | PTEN hamartoma tumor syndrome | Likely benign
(Mar 5, 2019) | reviewed by expert panel
FDA Recognized Database |
| - GRCh37:
- Chr10:89623029
- GRCh38:
- Chr10:87863272
| KLLN, PTEN | | Hereditary cancer-predisposing syndrome | Uncertain significance
(Dec 13, 2016) | criteria provided, single submitter |
| - GRCh37:
- Chr10:89623034
- GRCh38:
- Chr10:87863277
| KLLN, PTEN | | not provided, Hereditary cancer-predisposing syndrome | Uncertain significance
(Nov 30, 2019) | criteria provided, multiple submitters, no conflicts |
| - GRCh37:
- Chr10:89623036-89623038
- GRCh38:
- Chr10:87863279-87863281
| KLLN, PTEN | | Hereditary cancer-predisposing syndrome | Uncertain significance
(Apr 26, 2014) | criteria provided, single submitter |
| - GRCh37:
- Chr10:89623036
- GRCh38:
- Chr10:87863279
| KLLN, PTEN | | PTEN hamartoma tumor syndrome | Uncertain significance
(Mar 23, 2020) | reviewed by expert panel
FDA Recognized Database |
| - GRCh37:
- Chr10:89623045
- GRCh38:
- Chr10:87863288
| KLLN, PTEN | | not specified | Uncertain significance
(Aug 2, 2021) | criteria provided, single submitter |
| - GRCh37:
- Chr10:89623045-89623061
- GRCh38:
- Chr10:87863288-87863304
| KLLN, PTEN | | Hereditary cancer-predisposing syndrome | Uncertain significance
(Apr 8, 2019) | criteria provided, single submitter |
| - GRCh37:
- Chr10:89623045
- GRCh38:
- Chr10:87863288
| KLLN, PTEN | | not provided | Uncertain significance
(Dec 23, 2017) | criteria provided, multiple submitters, no conflicts |
| - GRCh37:
- Chr10:89623047-89623048
- GRCh38:
- Chr10:87863290-87863291
| KLLN, PTEN | | not provided | Uncertain significance
(Aug 29, 2016) | criteria provided, single submitter |
| - GRCh37:
- Chr10:89623047
- GRCh38:
- Chr10:87863290
| KLLN, PTEN | | Hereditary cancer-predisposing syndrome, not specified, not provided
| Uncertain significance
(Jul 19, 2021) | criteria provided, multiple submitters, no conflicts |
| - GRCh37:
- Chr10:89623050
- GRCh38:
- Chr10:87863293
| KLLN, PTEN | | Glioma susceptibility 2, Macrocephaly-autism syndrome, Familial meningioma,
Malignant tumor of prostate, Cowden syndrome 1, Hereditary cancer-predisposing syndrome,
not provided, Cowden syndrome 1 | Uncertain significance
(Oct 19, 2021) | criteria provided, multiple submitters, no conflicts |
| - GRCh37:
- Chr10:89623052
- GRCh38:
- Chr10:87863295
| KLLN, PTEN | | not specified | Uncertain significance
(Jan 7, 2020) | criteria provided, single submitter |
| - GRCh37:
- Chr10:89623052
- GRCh38:
- Chr10:87863295
| KLLN, PTEN | | not provided | Uncertain significance
(Sep 19, 2016) | criteria provided, single submitter |
| - GRCh37:
- Chr10:89623053
- GRCh38:
- Chr10:87863296
| KLLN, PTEN | | not provided | Uncertain significance
(Mar 7, 2016) | criteria provided, single submitter |
| - GRCh37:
- Chr10:89623054
- GRCh38:
- Chr10:87863297
| KLLN, PTEN | | Hereditary cancer-predisposing syndrome | Uncertain significance
(Apr 27, 2017) | criteria provided, single submitter |
| - GRCh37:
- Chr10:89623054
- GRCh38:
- Chr10:87863297
| KLLN, PTEN | | not provided, Hereditary cancer-predisposing syndrome | Uncertain significance
(Jan 3, 2017) | criteria provided, multiple submitters, no conflicts |
| - GRCh37:
- Chr10:89623054
- GRCh38:
- Chr10:87863297
| KLLN, PTEN | | Hereditary cancer-predisposing syndrome | Uncertain significance
(May 17, 2018) | criteria provided, single submitter |
| - GRCh37:
- Chr10:89623056
- GRCh38:
- Chr10:87863299
| KLLN, PTEN | | PTEN hamartoma tumor syndrome | Uncertain significance
(Oct 20, 2020) | reviewed by expert panel
FDA Recognized Database |