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Items: 1 to 20 of 36

1.

RNA-dependent RNA polymerases in the black-legged tick produce Argonaute-dependent small RNAs and regulate genes

(Submitter supplied) Small regulatory RNAs (sRNAs) are involved in anti-viral defense and gene regulation. Although RNA-dependent RNA Polymerases (RdRPs) play essential roles in sRNA biogenesis in nematodes, plants and fungi, their involvement in other animals remains controversial. We identify abundant classes of ~22nt sRNAs that require specific combinations of RdRPs and sRNA effector proteins (Argonautes or AGOs) expressed in the tick ISE6 cell line. more...
Organism:
Ixodes scapularis
Type:
Expression profiling by high throughput sequencing; Non-coding RNA profiling by high throughput sequencing
Platforms:
GPL30611 GPL18496
25 Samples
Download data: XLSX
Series
Accession:
GSE183810
ID:
200183810
2.

Effect of Anaplasma phagocytophilum infection on the micro RNA profile of Ixodes scapularis tick cells

(Submitter supplied) Ticks are blood feeding arthropod ectoparasites that transmit pathogens, which cause diseases in humans and animals worldwide. In the past ten decades, the continuous human exploitation of environmental resources and the increase in human outdoor activities has promoted contact with arthropod vectors normally present in the wild, resulting in increased transmission of vector-borne pathogens. In addition, vector populations are expanding in response to climate change and human interventions that impact reservoir host movement and human exposure to infected vectors. more...
Organism:
Ixodes scapularis
Type:
Non-coding RNA profiling by high throughput sequencing; Expression profiling by high throughput sequencing
Platform:
GPL21603
4 Samples
Download data: GTF
Series
Accession:
GSE79324
ID:
200079324
3.

Integrated metabolomics, transcriptomics and proteomics identifies metabolic pathways affected by Anaplasma phagocytophilum infection in tick cells

(Submitter supplied) Anaplasma phagocytophilum is an emerging zoonotic pathogen that causes human granulocytic anaplasmosis. These intracellular bacteria establish infection by affecting cell function in both the vertebrate host and the tick vector, Ixodes scapularis. Previous studies have characterized the tick transcriptome and proteome in response to A. phagocytophilum infection. However, in the post-genomic era, the integration of omics datasets through a systems biology approach allows network-based analyses to describe the complexity and functionality of biological systems such as host-pathogen interactions and the discovery of new targets for prevention and control of infectious diseases. more...
Organism:
Ixodes scapularis
Type:
Expression profiling by high throughput sequencing
Platform:
GPL18496
4 Samples
Download data: GTF
Series
Accession:
GSE68881
ID:
200068881
4.

B182: dsRdRP3_rep3

Organism:
Ixodes scapularis
Source name:
Ixodes scapularis embryonic 6 (ISE6) cells
Platform:
GPL30611
Series:
GSE183810
Download data
Sample
Accession:
GSM5571688
ID:
305571688
5.

B181: dsRdRP1_rep3

Organism:
Ixodes scapularis
Source name:
Ixodes scapularis embryonic 6 (ISE6) cells
Platform:
GPL30611
Series:
GSE183810
Download data
Sample
Accession:
GSM5571687
ID:
305571687
6.

B179: dsAgo-16_rep3

Organism:
Ixodes scapularis
Source name:
Ixodes scapularis embryonic 6 (ISE6) cells
Platform:
GPL30611
Series:
GSE183810
Download data
Sample
Accession:
GSM5571686
ID:
305571686
7.

B178: dsGFP_rep3

Organism:
Ixodes scapularis
Source name:
Ixodes scapularis embryonic 6 (ISE6) cells
Platform:
GPL30611
Series:
GSE183810
Download data
Sample
Accession:
GSM5571685
ID:
305571685
8.

B177: dsRdRP3_rep2

Organism:
Ixodes scapularis
Source name:
Ixodes scapularis embryonic 6 (ISE6) cells
Platform:
GPL30611
Series:
GSE183810
Download data
Sample
Accession:
GSM5571684
ID:
305571684
9.

B176: dsRdRP1_rep2

Organism:
Ixodes scapularis
Source name:
Ixodes scapularis embryonic 6 (ISE6) cells
Platform:
GPL30611
Series:
GSE183810
Download data
Sample
Accession:
GSM5571683
ID:
305571683
10.

B174: dsAgo-16_rep2

Organism:
Ixodes scapularis
Source name:
Ixodes scapularis embryonic 6 (ISE6) cells
Platform:
GPL30611
Series:
GSE183810
Download data
Sample
Accession:
GSM5571682
ID:
305571682
11.

B173: dsGFP_rep2

Organism:
Ixodes scapularis
Source name:
Ixodes scapularis embryonic 6 (ISE6) cells
Platform:
GPL30611
Series:
GSE183810
Download data
Sample
Accession:
GSM5571681
ID:
305571681
12.

B172: dsRdRP3_rep1

Organism:
Ixodes scapularis
Source name:
Ixodes scapularis embryonic 6 (ISE6) cells
Platform:
GPL30611
Series:
GSE183810
Download data
Sample
Accession:
GSM5571680
ID:
305571680
13.

B171: dsRdRP1_rep1

Organism:
Ixodes scapularis
Source name:
Ixodes scapularis embryonic 6 (ISE6) cells
Platform:
GPL30611
Series:
GSE183810
Download data
Sample
Accession:
GSM5571679
ID:
305571679
14.

B169: dsAgo-16_rep1

Organism:
Ixodes scapularis
Source name:
Ixodes scapularis embryonic 6 (ISE6) cells
Platform:
GPL30611
Series:
GSE183810
Download data
Sample
Accession:
GSM5571678
ID:
305571678
15.

B168: dsGFP_rep1

Organism:
Ixodes scapularis
Source name:
Ixodes scapularis embryonic 6 (ISE6) cells
Platform:
GPL30611
Series:
GSE183810
Download data
Sample
Accession:
GSM5571677
ID:
305571677
16.

B061: 5'TriP enriched

Organism:
Ixodes scapularis
Source name:
Ixodes scapularis embryonic 6 (ISE6) cells
Platform:
GPL18496
Series:
GSE183810
Download data
Sample
Accession:
GSM5571676
ID:
305571676
17.

B060: oxidized

Organism:
Ixodes scapularis
Source name:
Ixodes scapularis embryonic 6 (ISE6) cells
Platform:
GPL18496
Series:
GSE183810
Download data
Sample
Accession:
GSM5571675
ID:
305571675
18.

B059: No treatment

Organism:
Ixodes scapularis
Source name:
Ixodes scapularis embryonic 6 (ISE6) cells
Platform:
GPL18496
Series:
GSE183810
Download data
Sample
Accession:
GSM5571674
ID:
305571674
19.

B058: dsRdRP3

Organism:
Ixodes scapularis
Source name:
Ixodes scapularis embryonic 6 (ISE6) cells
Platform:
GPL18496
Series:
GSE183810
Download data
Sample
Accession:
GSM5571673
ID:
305571673
20.

B057: dsRdRP1

Organism:
Ixodes scapularis
Source name:
Ixodes scapularis embryonic 6 (ISE6) cells
Platform:
GPL18496
Series:
GSE183810
Download data
Sample
Accession:
GSM5571672
ID:
305571672
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db=gds|term=(txid6945[Organism:noexp])%20AND%20gds_sra[filter]|query=1|qty=2|blobid=MCID_61b12f56751eac12ee5d3832|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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