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Items: 18

1.
Full record GDS5082

Fetal alcohol spectrum disorder model: whole embryo

Analysis of embryos treated with ethanol in embryo medium from 2 hours post fertilization (hpf) to 8hpf. FASD occurs when pregnant mothers consume alcohol, causing embryonic ethanol exposure and characteristic developmental defects. Results provide insight into molecular basis of FASD pathogenesis.
Organism:
Danio rerio
Type:
Expression profiling by array, count, 2 protocol sets
Platform:
GPL1319
Series:
GSE48380
14 Samples
Download data: CEL, CHP
2.
Full record GDS5025

Age and gender effect on brain

Analysis of brain from young (7.5-8.5 months) and old (31-36 months) wildtype males and females. Brains are sexually dimorphic in adults. Results provide insight into the molecular mechanisms associated with brain aging across gender.
Organism:
Danio rerio
Type:
Expression profiling by array, transformed count, 2 age, 2 gender sets
Platform:
GPL1319
Series:
GSE53430
12 Samples
Download data: CEL
3.
Full record GDS5357

Ethanol effect on embryonic eyes: time course

Analysis of eyes from 24-48 hour post-fertilization embryos exposed to 1.5% ethanol. Ethanol exposure during retinal neurogenesis associated with microphthalmic defects. Results provide insight into molecular mechanisms underlying ethanol exposure-mediated developmental retinal defects.
Organism:
Danio rerio
Type:
Expression profiling by array, count, 2 agent, 5 time sets
Platform:
GPL1319
Series:
GSE51427
9 Samples
Download data: CEL, CHP
4.
Full record GDS3735

Hand2 loss of function effect on embryonic heart

Analysis of Hand2 mutant embryo hearts at 19 hpf. Hand2 is a myocardial transcription factor essential for fusion of bilateral cardiomyocyte populations moving toward the embryonic midline. Results provide insight into downstream components of the Hand2 pathway that mediates cardiac morphogenesis.
Organism:
Danio rerio
Type:
Expression profiling by array, count, 2 genotype/variation sets
Platform:
GPL1319
Series:
GSE23381
6 Samples
Download data: CEL
5.
Full record GDS3719

Transcription factor Ovo1 depletion effect on 12 hour post-fertilization embryos

Analysis of wild-type embryos injected with Ovo1 morpholino antisense oligos. At 12 hpf, the Ovo1 morphants begin showing neural crest (NC) defects wherein a subset of NC cells aggregates in the dorsal midline above the neural tube. Results provide insight into the role of Ovo1 in NC migration.
Organism:
Danio rerio
Type:
Expression profiling by array, count, 2 genotype/variation sets
Platform:
GPL1319
Series:
GSE21539
6 Samples
Download data: CEL
6.
Full record GDS3623

Heart regeneration in zebrafish

Analysis of hearts of zebrafish 1 to 7 days following partial heart amputation. Unlike mammals, zebrafish hearts display an extensive regenerative capacity. Results provide insight into the molecular basis of this regenerative capacity.
Organism:
Danio rerio
Type:
Expression profiling by array, transformed count, 2 protocol, 5 time sets
Platform:
GPL1319
Series:
GSE17993
15 Samples
Download data: CEL
DataSet
Accession:
GDS3623
ID:
3623
7.
Full record GDS3824

Pineal gland development

Analysis of pineal gland across 5 developmental stages (3 larval, 2 adult) during the day and night. Pineal gland is a site of melatonin production, contains photoreceptor cells, and acts as a circadian clock pace maker. Results provide insight into the molecular basis of pineal gland development.
Organism:
Danio rerio
Type:
Expression profiling by array, count, 5 age, 2 development stage, 2 time, 2 tissue sets
Platform:
GPL1319
Series:
GSE13371
69 Samples
Download data: CEL
8.
Full record GDS3464

SPT5 mutant embryos

Analysis of fog-sk8 mutant embryos containing a severe truncation of Spt5. Spt5 regulates transcription elongation. Results identify Spt5 target genes during development.
Organism:
Danio rerio
Type:
Expression profiling by array, transformed count, 2 genotype/variation sets
Platform:
GPL1319
Series:
GSE12826
6 Samples
Download data: CEL
9.
Full record GDS2965

Embryonic heart response to retinoic acid and dioxin: time course

Analysis of hearts from embryos treated for up to 12 hours with retinoic acid (RA) or 2,3,7,8 tetrachlorodibenzo-p-dioxin (TCDD). Zebrafish embryos treated with RA or TCDD develop cardiac malformation and heart failure.
Organism:
Danio rerio
Type:
Expression profiling by array, transformed count, 4 agent, 4 time sets
Platform:
GPL1319
Series:
GSE9020
48 Samples
Download data: CEL, EXP
DataSet
Accession:
GDS2965
ID:
2965
10.
Full record GDS2928

2,3,7,8-tetrachlorodibenzo-p-dioxin effect on the ovary: dose response (II)

Analysis of ovaries following exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) at concentrations of up to 100 parts per billion (ppb). TCDD is a reproductive toxicant and endocrine disruptor in vertebrates. Results provide insight into molecular mechanisms underlying TCDD toxicity.
Organism:
Danio rerio
Type:
Expression profiling by array, count, 4 dose sets
Platform:
GPL1319
Series:
GSE4859
4 Samples
Download data: CEL, EXP
11.
Full record GDS2927

2,3,7,8-tetrachlorodibenzo-p-dioxin effect on the ovary: dose response (I)

Analysis of ovaries following exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) at concentrations of up to 100 parts per billion (ppb). TCDD is a reproductive toxicant and endocrine disruptor in vertebrates. Results provide insight into molecular mechanisms underlying TCDD toxicity.
Organism:
Danio rerio
Type:
Expression profiling by array, count, 4 dose sets
Platform:
GPL1319
Series:
GSE4859
4 Samples
Download data: CEL, EXP
12.
Full record GDS2550

Recycling factor p110 mutation effect on embryonic development

Analysis of 3 and 5-day egy mutant embryos, which contain a mutation in recycling factor p110. This mutation leads to microcephaly and thymus hypoplasia. U4/U6 snRNPs are disrupted in egy mutants. Results provide insight into the mechanisms underlying these developmental defects.
Organism:
Danio rerio
Type:
Expression profiling by array, count, 2 age, 2 genotype/variation sets
Platform:
GPL1319
Series:
GSE5586
10 Samples
Download data
13.
Full record GDS2556

Embryonic retinal pigment epithelium

Analysis of microdissected embryonic retinas with or without the retinal pigment epithelium (RPE). The RPE is a thin layer of cells that underlies the neural retina and supports the function and development of photoreceptors. Results provide insight into the development of the RPE.
Organism:
Danio rerio
Type:
Expression profiling by array, count, 2 tissue sets
Platform:
GPL1319
Series:
GSE5048
6 Samples
Download data: CEL, DAT
14.
Full record GDS2192

Titin mutation effect on embryonic muscles

Analysis of trunk and tail muscles of runzel (ruz) mutant embryos at 3.5 days post fertilization (dpf). Ruz mutants carry a mutation in the titin gene resulting in muscle degeneration and embryonic lethality. Results provide insight into the pathogenesis of titin muscular dystrophy.
Organism:
Danio rerio
Type:
Expression profiling by array, count, 2 genotype/variation sets
Platform:
GPL1319
Series:
GSE4585
6 Samples
Download data
DataSet
Accession:
GDS2192
ID:
2192
15.
Full record GDS2425

Heart response to chronic constant hypoxia

Analysis of hearts of wild type Tuebingen animals subjected to chronic constant hypoxia.
Organism:
Danio rerio
Type:
Expression profiling by array, count, 2 stress sets
Platform:
GPL1319
Series:
GSE4989
10 Samples
Download data: CEL, EXP
16.
Full record GDS1797

TCDD effect on regenerating fin: time course

Analysis of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) exposed caudal fins at various time points up to 5 days post amputation. TCDD prevents caudal fin regeneration. Results provide insight into the pathways required for fin regeneration and the mechanisms of TCDD toxicity.
Organism:
Danio rerio
Type:
Expression profiling by array, count, 2 agent, 3 time sets
Platform:
GPL1319
Series:
GSE3667
18 Samples
Download data: CEL
DataSet
Accession:
GDS1797
ID:
1797
17.
Full record GDS1771

MicroRNA miR-430 effect on maternal-zygotic (MZ) dicer mutant embryos

Analysis of maternal-zygotic (MZ) dicer mutant embryos that lack miR-430 and mutants rescued with miR-430. MZdicer mutants cannot generate mature miRNAs; miR-430 accumulates during maternal-to-zygotic transition and regulates morphogenesis during early development. Results identify miR-430 targets.
Organism:
Danio rerio
Type:
Expression profiling by array, count, 3 development stage, 2 genotype/variation, 2 protocol sets
Platform:
GPL1319
Series:
GSE4201
15 Samples
Download data: CEL, EXP
DataSet
Accession:
GDS1771
ID:
1771
18.
Full record GDS1404

Regenerating retina: time course

Expression profiling of lesioned retina at various time points up to 14 days after injury. Results provide insight into the molecular mechanisms that enable the regeneration of injured retinas in adult anamniotes.
Organism:
Danio rerio
Type:
Expression profiling by array, count, 4 disease state, 3 protocol, 6 time, 2 tissue sets
Platform:
GPL1319
Series:
GSE3303
12 Samples
Download data
DataSet
Accession:
GDS1404
ID:
1404
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